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juliensage.bsky.social
Stanford, cell cycle, RB, cancer, SCLC, mouse models
9 posts 312 followers 228 following
Prolific Poster

It is incredible to see so many passionate researchers at the Stanford Cancer Institute Retreat today!

Cool paper from Crabtree and Gray labs: www.biorxiv.org/content/10.1...

....and to be followed by broad investment in science as the columnist suggests. www.theguardian.com/commentisfre...

Interested in aging? Super excited about this upcoming Keystone meeting!! 🧪🌲🌲 Aging: Immune Function and Organ Health -- Banff, Canada in 2026!!! ✨✨ Joint meeting with the Keystone Innate Immunity meeting! #aging #immunity @keystonesymposia.bsky.social www.keystonesymposia.org/conferences/...

New preprint from the Oliver Lab @tgoliver.bsky.social! We uncover a hillock-like cell state in squamous tumors using GEMMs, organoids, and human data while digging into the mechanisms that regulate cell state plasticity: KLF4 plays a crucial role! Check it out at: www.biorxiv.org/content/10.1...

#Cancer research needs #neuroscience and neuroscientists. Sharing some thoughts on #CancerNeuroscience, together with Frank Winkler. www.nature.com/articles/s41...

Abstracts are due TOMORROW! Please share!

Pics every 60 seconds from totality to end of deep penumbra eclipse. Watched totality and first part of this live and then let the telescope automate the rest. Totally worth missing a little sleep! #lunareclipse

Integrative spatial analysis reveals tumor heterogeneity and immune colony niche related to clinical outcomes in small cell lung cancer

@cedric-blanpain.bsky.social we are looking forward to your presentation at #SCC25 in Malta this Sept!☀️Please share with your followers to let them know registration & abstract submission is open! Find out more: bit.ly/49sCfJp

Congrats Luke!!

Congratulations to winners of The Brain Prize 2025! Professors @michellemonje.bsky.social, @stanfordmedicine.bsky.social and @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital, have pioneered the field of Cancer Neuroscience. Learn more: brainprize.org/winners/canc...

The discovery that some malignant cancers form connections with the brain’s circuitry that help fuel tumor growth could help researchers better understand how to treat or stop the cancers altogether. @michellemonje.bsky.social @juliensage.bsky.social Watch: stan.md/cancerneuro #BrainCancer

Our excellent host, Julien Sage, sharing a surprising/unexpected role for T cells in the biology of small cell lung cancer …thanks Julien and Kevin for organising such a great @fusionconf.bsky.social (mouse models of cancer) conference!!

Our latest piece "Decoding Melanoma’s Cellular Mosaic to Unlock Immunotherapy Potential" is available online: authors.elsevier.com/a/1khFK3QxxS... and will soon be published in @cp-trendscellbio.bsky.social. Thanks to @pozniakjoanna.bsky.social for taking the lead! Our Cover design proposal is below

We love working with the furry mice #AMC25 and working out with the fuzzy tennis balls!

This evening focused on insights into heterogeneity & plasticity: 💥 Tuomas Tammela on cell state interrogation 🧪 Laura Attardi on p53 in cell state transitions 🧬 Frederic De Sauvage on tumor cell plasticity in colorectal cancer Thanks to our incredible speakers for their contributions! 🙌 #AMC25

We took a deep dive into cancer progressions & metastasis this morning at #AMC25: 🧬Chris Marine on melanoma progression & therapy resistance 🐭 Eran Andrechek & Peter Westcott with cutting edge mouse models 🫁Katie Politi on progression & resistance in lung cancer 🌊Plus an exciting Catamaran tour⛵️

Few universities have released public statements about their strategies, so prospective graduate students have remained largely in the dark about which institutions are cutting back. https://go.nature.com/4iiPX4F

Delighted to share the published version of this work from brilliant #CancerNeuroscience post-doc Tara Barron detailing GABAergic neuron-to-glioma synapses in #DIPG/#DMG. 🧵 Open access link: www.nature.com/articles/s41...

Excited to share this new work led by postdoc Brendan Floyd, deep mapping of cell-surface protein interactomes of T and B cells reveals maverick mitochondrial proteins and immune modulatory complexes. www.biorxiv.org/content/10.1...

On January 6th, 1995, my (now ex) wife and I boarded a flight from Heathrow to JFK on a one way ticket. We had two suitcases and about $900 in cash - this was everything we owned and we were moving to the US. We thought it was maybe for 2-3 years. I had visited the US once, for a conference, and

Two more weeks to apply to join us in Paris ! research.pasteur.fr/en/call/call...

Registration is open for our summer FASEB #Ferroptosis Conference July 27 - 31, 2025. We have a terrific line up of speakers and it's going to be amazzzing! Come join us for this historic first meeting! Please help us to spread the word. 🤩 shorturl.at/QA6T1

Awesome paper @nature.com‬ from Leanne Li's group @crick.ac.uk on the role of electrical activity in small cell lung cancer (SCLC) development and how non-neuroendocrine SCLC cells support the growth of neuroendocrine SCLC. www.nature.com/articles/s41...

Do you have a background in cancer research or neuroscience? The Venkatesh Lab is expanding its team & seeking talented individuals at all levels. If you're passionate about cutting-edge research at the intersection of cancer and neuroscience, we'd love to hear from you!

With cancer research and care a top priority, Stanford Medicine’s leaders are charting a bold course to redefine how we understand, prevent and treat the disease. stanmed.stanford.edu/leaders-prio...

We are looking for PhD students and/or postdocs that want to join us to study the metabolism of metastasizing cancer cells with cutting-edge spatial and single cell technologies. fendtlab.sites.vib.be/en

Excited to be in Lyon for the 6th International Cancer Symposium. Great schedule, with 650 attendees, and great food!

Ever wondered how #mitochondria fragmentation comes about during #ferroptosis ? Read our new paper on Drp1-mediated promotion of ferroptotic #celldeath. Great @cecad.bsky.social collaboration with Ana Garcia Saez! rdcu.be/d7L66

🧪 fellow scientists, any advice on a good primer for scRNAseq analysis. Not just the coding part, but the math behind it as well.

Very excited about this new work from our lab! Explainer thread coming soon @minetoota.bsky.social

The VIDA COFUND Postdoctoral Programme is now open at @vhio.bsky.social . Please visit vhiovidaprogramme.eu for more info and join any of our #cancer #research laboratories in Barcelona! #oncosky #medsky 🧪 malumbreslab.org

Yes, they can hallucinate papers that don't exist, discuss results that seem to be imaginary, and can be confusing and inconsistent. But talking to tenured professors may still be helpful

More phagocytosis from microglia, more Interferon-gamma activity, maybe inhaling Xenon could be useful to treat brain metastases too (SCLC or other cancers)...

Interested in brain aging? We are super excited to share our new review!! "Brain aging and rejuvenation at single-cell resolution" 🧪🧠 Massive CONGRATS to Eric Sun, Rahul Nagvekar, and Angie Pogson, three phenomenal graduate students in the lab!! authors.elsevier.com/sd/article/S...

DLL3 downregulation could be the expected mechanism of resistance to the tarlatamab BiTE in SCLC. This small study shows SCLC subtype switching, suggesting that intra-tumoral heterogeneity with pre-existing DLL3-low ASCL1-neg SCLC cells is an “easier” mechanism? Interesting! tinyurl.com/ye29dx6v

Thoughts on this? >> IDEAYA Biosciences Enters Exclusive License with Hengrui Pharma for SHR-4849, a Novel Phase 1 DLL3 Topo-I-Payload ADC Targeting SCLC and NET Solid Tumors: Exclusive global license outside of Greater China for SHR-4849,… >> Comment below! #healthtech #AI #mhealth #industry40 #IoT

Excited to report that Joy Bergelson (bergelsonlab.org) and I will be running a brand new GRC conference on the Function of Evolving Systems in the summer of 2026. The 2028 one will be chaired by Mikhail Tikhonov (physics.wustl.edu/people/mikha...) and @asanchezlab.bsky.social! Stay tuned!

Happy New Year! I wish everyone many discoveries in 2025, with fun science! First Bluesky post from Paris!!