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#macrovsmicro gray-tan to red-brown mass involving adrenal gland, residual adrenal gland with yellow-orange cortex #gupath #pathsky

submitted 86 days ago • 1 comment

#slidearchivenseries urothelial carcinoma, plasmacytoid variant #gupath #pathsky 📸 cystectomy after TURBT, irregular area of ulceration on bladder wall with no distinct mass, submitted entirely 🔬deeply infiltrating, discohesive small clusters and single tumor cells

submitted 86 days ago • 0 comments

#slidearchivenseries urothelial carcinoma, plasmacytoid variant 📸 cystectomy after TURBT, area of mucosal puckering/ulceration with no distinct mass, submitted entirely 🥷 sneaky tumor cells can invade as single cells, often deeply infiltrative with minimal stromal reaction #gupath #pathsky

submitted 86 days ago • 1 comment

Check out our Current Issue!! Figure from "Claudin 18.2 Immunohistochemistry Expression in Gastric Cancer: A Systematic Review” by Lop Gros, et al. 🔗 Read the full article here: journals.lww.com/appliedimmun...

submitted 3 days ago • 1 comment

chromophobe renal cell carcinoma showing its true colors! #gupath #kidneytumor #pathsky #pathoutpic 🎨 collodial iron special stain 🔵💥

submitted 88 days ago • 0 comments

#macrovsmicro partial nephrectomy, variegated white-tan to yellow-brown mass #gupath

submitted 88 days ago • 1 comment

IU Pathology and IUHMG are expanding! We're recruiting a GI-focused surgical pathologist (≥5 years post-fellowship) to join our team. Additional subspecialty expertise welcome! #gipath #pathtwitter #pathX 🔗 indiana.peopleadmin.com/postings/28535

submitted 6 days ago • 0 comments

IU Pathology and IUHMG are recruiting anatomic pathologists in: 🔬 Pediatric Pathology 🔬 Head & Neck Pathology 🔬 Thoracic-Pulmonary Pathology 🔬 Dermatopathology 🔬 Gastrointestinal Pathology Additional subspecialty training is welcome! 🔗 indiana.peopleadmin.com/postings/28097

submitted 6 days ago • 0 comments

In #GUPATH we talk about comedo necrosis in high grade prostate cancer being associated with intraductal spread - but not always - this is a lymph node metastasis, so no intraductal spread here!

submitted 12 days ago • 0 comments

Follow us to stay connected and up to date! #pathsky @katcollmd.bsky.social Where to find us: ➡️ Website: journals.lww.com/appliedimmun... ➡️ Twitter: x.com/aimmjournal ➡️ Instagram: instagram.com/aimmjournal ➡️ Bluesky: bsky.app/profile/aimm...

submitted 19 days ago • 0 comments

#PathSky 30F with shoulder mass. Nice example of low-grade fibromyxoid sarcoma, with heavily collagenized areas and a very abrupt transition to more cellular nodules with a whorling pattern and a well-developed vasculature. MUC4 IHC is confirmatory. This case has another helpful H+E feature (below)

submitted 17 days ago • 1 comment

🚨 #publicationalert #gupath We developed a deep learning-based classifier to distinguish renal oncocytoma from low-grade oncocytic tumor (LOT) in whole slide images with high accuracy. Link to our article: doi.org/10.5858/arpa...

submitted 15 days ago • 0 comments

#macrovsmicro orchiectomy, tan-white, firm, homogeneous, faintly lobulated, well-delineated mass abutting the rete testis #gupath #pathsky #pathoutpic 🩺 increased testicular pain and swelling, evaluation for torsion; 3.9 cm mass on ultrasound 🧪 AFP 3.8, HCG 2.5

submitted 15 days ago • 1 comment

#macrovsmicro radical nephrectomy, sarcomatoid components comprise sizeable areas displaying dense, tan-pink, or white areas within the tumor, typically with a firm and fleshy texture on cut surface #gupath #pathsky #kidneytumor

submitted 15 days ago • 1 comment

📢 Exciting news! @intsocuropath.bsky.social and @GU_Path_Society are hosting an Expert Consultation Conference on IDC-P during #USCAP2025! 🗓 Saturday, March 22, 2025 ⏰ 1-5 PM 📍 Boston (in-person, free for members) 🔗 Register: www.eventbrite.com/e/expert-con...

submitted 60 days ago • 0 comments

Membranous Staining of CD10 Is Related to Steatosis Changes in Hepatocellular Carcinoma: An Investigation of CD10 Stainning in Hepatocellular Carcinoma, Focal Nodular Hyperplasia, and Intrahepatic Cholangiocarcinoma journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

The Prevention of Fatal Tauopathy in a Mouse Model of Alzheimer Disease by Blocking BCL2 journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

Claudin 18.2 Immunohistochemistry Expression in Gastric Cancer: A Systematic Review journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

Immunohistochemical Expression of PAX8 in Central Nervous System Hemangioblastomas: A Potential Diagnostic Pitfall for Neuropathologists journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

Changes in HER2 Amplification Status for Breast Cancer Patients After Immunohistochemistry Directed In Situ Hybridization journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

TP53 Alterations Are an Independent Adverse Prognostic Indicator in Pseudomyxoma Peritonei of Appendiceal Origin Following Cytoreductive Surgery and Intraperitoneal Chemotherapy journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

Overexpression of MAGE-A2 is Related to the Malignant Degree and Progression of Disease in Patients With Clear Cell Renal Cell Carcinoma journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

The Relationship of PRAME Expression with Clinicopathologic Parameters and Immunologic Markers in Melanomas: In Silico Analysis journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

Smooth Muscle Myosin Heavy Chain Expression in Nodal and Extranodal Follicular Dendritic Cell Sarcoma journals.lww.com/appliedimmun...

submitted 19 days ago • 0 comments

talk about an udder-ly unexpected finding 🐄 #pathpuns #MooOlogy

submitted 21 days ago • 0 comments

#slidearchiveseries embryonal carcinoma #gupath #pathsky 🔬 pseudoendodermal sinus-like 🎨 OCT4 📑 pubmed.ncbi.nlm.nih.gov/29129333/ 🏥 history of epididymo-orchitis; enlarged testicle with a heterogeneous mass-like area (increasing in size), serum tumor markers not known

submitted 86 days ago • 0 comments

#macrovsmicro radical orchiectomy, gray-white to red-brown, heterogeneous, focally hemorrhagic and focally degenerative mass #gupath #pathsky #testicularcancer

submitted 86 days ago • 2 comments

#slidearchiveseries paraganglioma of urinary bladder #gupath #pathsky 🔬 polygonal cells with granular cytoplasm in Zellballen pattern 🎨 SYN/CG/often GATA3 (pitfall) 🧬assoc with germline SDH mutation 🤔confused with urothelial ca, granular cell tumor, melanoma

submitted 22 days ago • 0 comments

#PathSky 43F with a solitary lung mass. Relatively circumscribed, nests and interesting micropapillae of lightly eosinophilic epithelioid cells. Negative for everything except TFE3. Dx?

submitted 31 days ago • 1 comment

Need an Update on Urological Pathology? Please join the International Academy of Pathology (Singapore Division) & International Society of Urological Pathology (SG-IAP/ISUP) Joint Symposium – Advances in Urological Pathology. 🔗 Register (free): QR code in program: acrobat.adobe.com/id/urn:aaid:...

submitted 31 days ago • 0 comments

#PathSky Slowly growing superficial leg mass, 38M. Well-circumscribed, phleboliths, thrombosed vessels, cellular spindle cell areas, cavernous vascular channels. Dx?

submitted 32 days ago • 1 comment

53 yo F, bladder mass. Bladder adenocarcinoma is far less common than urothelial. Arises in the setting of cystitis glandularis with intestinal metaplasia, as urachal carcinoma at the bladder dome or may represent local extension, particularly from a colorectal primary. #PathSky

submitted 31 days ago • 1 comment

📚 #readinglist #mustreads Pathologists see organs in living color, but why do they look that way? This article unpacks the pigments behind the pathology! #pathart 📖 Have you read it? If not, add it to your list!! doi.org/10.5858/arpa...

submitted 32 days ago • 0 comments

📢 Exciting news! Thrilled to share I will be taking on the role of AIMM’s Social Media Editor! Grateful for this opportunity and excited to foster connections in the digital space and engage with our path community. #onlineaheadofprint #IHCpath 🔗 journals.lww.com/appliedimmun...

submitted 32 days ago • 0 comments

#slidearchiveseries nephrogenic adenoma #gupath #pathsky #pathoutpic 🏥 prior urothelial injury (surgery, calculi, trauma) sites: bladder > urethra > ureter 🔬 metaplastic lesion, multiple morphological patterns 🎨 PAX8, AMACR, GATA3 (40%), PSA (weak) (+) ⚠️ exclude prostate & bladder ca

submitted 87 days ago • 0 comments

#slidearchiveseries urothelial carcinoma, micropapillary subtype #gupath #pathsky #pathoutpic ☝🏼distinguish from retraction artifact ✅ multiple small nests floating within single lacunae ✅ back-to-back lacunae ✅ presence of ring formations

submitted 87 days ago • 0 comments

#slidearchiveseries urothelial carcinoma with extensive squamous differentiation #gupath #pathsky #pathoutpic ☝🏼 identifiable urothelial component (may only be carcinoma in situ) ✌🏼 recommended to report percentage of squamous component

submitted 87 days ago • 0 comments

#slidearchiveseries prostatic adenocarcinoma with mucinous component #gupath #pathsky ✅ prognosis similar to non-mucinous cancers of similar Gleason score ✅ subtract mucin, grade based on underlying architecture ✅ mucin present (≤25 🆚 >25%) ✅ final classification on resection

submitted 87 days ago • 0 comments

👩🏻‍💻 #readinglist #pathreads 📊 Inconsistent examination in post-NACT cystectomies with no gross lesion 🗳️ Majority supports standardized protocols #gupath #pathsky 📄 academic.oup.com/ajcp/article...

submitted 36 days ago • 0 comments

🚨 #publicationalert #gupath Our study shows Sertoliform cystadenomas, reclassified as Sertoli cell tumors NOS in the latest WHO, lack key Sertoli cell tumor markers, suggesting they are distinct. onlinelibrary.wiley.com/doi/10.1111/...

submitted 36 days ago • 0 comments

🚨 ISUP Presents..... 🔬 Arndt Hartmann on "Role of uropathologist in hereditary urologic tumors" 📅 25 February 2025 at 12pm EST via Zoom Register here: us06web.zoom.us/webinar/regi...

submitted 38 days ago • 0 comments

#PathSky 76M with a testicular mass. The outside was quite convinced this was a germ cell tumor with ITGCN, but it was resolutely negative for germ cell markers, and a broad panel of other markers. What to do next? NGS? Methylation? NGS + methylation?

submitted 41 days ago • 2 comments

Helpful tips from a 25-year Annual Meeting veteran - great for everyone, not just people new to the meeting! @rovingatuscap.bsky.social #USCAP2025 youtu.be/KTkgw1ds4o8

submitted 41 days ago • 1 comment

“Those who would hold your early mistakes against you are the folks whose opinions you should ignore anyway.” - Joan Westenburg

submitted 43 days ago • 0 comments