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katherinedonovan.bsky.social
🇳🇿 Kiwi | Scientist | Targeted Protein Degradation | Chemoproteomics | Tweets are my own
6 posts 528 followers 68 following
Regular Contributor

I am excited to be hosting Prof. Jian Jin in our TPD webinar series on March 6th at 12pm! Join us to hear about his lab's strategies to target undruggable proteins

Popularity of current DIA data analysis tools (vendor-independent, based on citations of initial publication) Updated for 2024:

Congratulations to @alesalerno.bsky.social from University of Dundee CeTPD and Christine Ng from @stanford-chemh.bsky.social who have been selected as recipients of our conference travel scholarships to attend the Proximity-based Therapeutics Keystone conference @keystonesymposia.bsky.social!

Please share widely - we are hiring, come join our team!

Nice write-up of the successful SMART TPD symposium in Shenzhen, China - co-organised with Nat Gray, Nieng Yan, Peng Chan and Shixiang Yan. So enjoyed the opportunity. #TPD #SMARTsymposia www.szbl.ac.cn/en/infomatio...

Join us for the final TPD webinar of 2024 on 12/19. @fleurmferguson.bsky.social & Eric Wang - "ZBTB11 Degraders Target Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC" Slava Ziegler - "Targeting IDO1 by monovalent degraders exploiting the native IDO1 degradation mechanism"

Join us for the final TPD webinar of 2024 on 12/19. @fleurmferguson.bsky.social & Eric Wang - "ZBTB11 Degraders Target Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC" Slava Ziegler - "Targeting IDO1 by monovalent degraders exploiting the native IDO1 degradation mechanism"

I really enjoyed chairing the #AACRCICR session today focused on bivalent degraders. Thank you to Michael Erb, Mikko Taipale, and Xin Zhou for the beautiful talks! #AACRchem24

Excited to share our work investigating how ligand residence time influences targeted protein degradation outcomes at scale, and how we can combine kinetic scout degrader approaches with mathematical modeling to accelerate hit finding and optimization! onlinelibrary.wiley.com/doi/abs/10.1...

‘Dark proteome’ survey reveals thousands of new human genes | Science www.science.org/content/arti...

Through a series of cryo-EM structures, this study shows how an E2 and ubiquitin itself can play a "structural" role to specify ubiquitin linkage. 🧪 Lovely work by Katrina Warner, @moritzhunkeler.bsky.social @kheewoongbaek.bsky.social, @katherinedonovan.bsky.social and others in the Fischer Lab!

📯📯 Chemical Biology starter pack 📯📯 140 PIs & groups posting primary research in chemical biology. Please reskeet (?) & reply to this post if you want to be added! go.bsky.app/KLrTWoj Let's make ChemBioSky even greater again! #realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange

Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn

Thank you to the SMART organizing team for putting on a fantastic #TPD conference in China last week!

The starter pack the TPD community has been waiting for: go.bsky.app/CE2P2Yh

Chemoproteomics starter pack, thanks mostly to @stephanhacker2.bsky.social's strong network go.bsky.app/JKJ1ZHt