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kennethwitwer.bsky.social
Extracellular vesicle and RNA enthusiast; President, International Society for Extracellular Vesicles (ISEV); life-long learner; consultant
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A great write up on our recent work in PNAS attempting to understand metabolic drivers of sleep, led by @ncons95.bsky.social ! uknow.uky.edu/research/fue...

Next #EVClub is with Tamás Visnovitz and @editbuzas.bsky.social: A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes) Apr 2, 11 AM EDT/17.00 CEST Need the login? Sign up: surveymonkey.com/r/EVClubISEV @isev.org

Next #EVClub: Silvia Cappello on #EV molecular cues in human brain development pubmed.ncbi.nlm.nih.gov/39302835/ Wed March 19 12 noon EST/17.00 CET Need the login? www.surveymonkey.com/r/EVClubISEV W/Tsuneya Ikezu, #EViNS, #ISEV Extracellular Vesicles in Nervous Systems Special Interest Group

In HIV infection, U6 snRNA leaves the nucleus and is packaged into extracellular vesicles to aid in intercellular communication www.science.org/doi/10.1126/... @kennethwitwer.bsky.social

thank you @kennethwitwer.bsky.social and @isev.org for continuing your #EVClub! Just before #ISEV2025 in Vienna/Austria, Carla Tripisciano and Johannes Thaler from ASEV (with intro from Rienk Nieuwland) presented kind of "history" of #extracellularvesicles in terms of their function in coagulation 😎

Next #EVClub: "A century of evidence for highly coagulant tissue factor/activated factor VII complex-exposing EVs in body fluids" See also: doi.org/10.1182/bloo... and ashpublications.org/blood/articl... Wed 12 noon EST/18.00 CET Need the login? Sign up: surveymonkey.com/r/EVClubISEV

Next #EVClub: Joe Brealey shines "a light on fluorescent EV dyes: Evaluating efficacy, specificity and suitability by nano-flow cytometry" isevjournals.onlinelibrary.wiley.com/doi/10.1002/... Wed Feb 26 12 noon EST/18.00 CET Need the login? www.surveymonkey.com/r/EVClubISEV #ExtracellularVesicles

The aging human brain exhibits reduced cerebrospinal fluid flow during sleep due to both neural and vascular factors

The 2025 edition of the #EMBOEVs EMBO practical course on #extracellularvesicles has started! Our highly distinguished keynote speaker Edit Buzas @editbuzas.bsky.social enlightens the participants on the large diversity of EVs.

This week's #EVClub features "Direct intercellular vesicle exchange between adjacent cells" www.biorxiv.org/content/10.1... With Jun Yamashita and group Wed Feb 19, 11 AM Japan, 10 AM Beijing, 1 PM Melbourne; Tuesday Feb 18, 9 PM EST Need the login? www.surveymonkey.com/r/EVClubISEV

The no cost extension button is back and at least some are being granted. If this applies to you, go for it. PLEASE SHARE

ICYMI: #EVClub of #ISEV and #EViNS. Carla Lopes presents “#ExtracellularVesicles improve GABAergic transmission in Huntington's disease iPSC-derived neurons” (Theranostics, 2023: www.thno.org/v13p3707.htm). To join the mailing list: www.surveymonkey.com/r/EVClubISEV @isev.org youtu.be/c9oFoLy3xdU