kgoepfrich.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

I'm happy to share this roadmap towards the synthesis of life! It is the result of one of the best workshops I ever attended, where scientists across biology, chemistry, and physics came together to map out the key challenges to synthesize life. Enjoy! www.sciencedirect.com/science/arti...

submitted 17 days ago • 2 comments

New Master's programme in Heidelberg! Please share with interested students

submitted 25 days ago • 1 comment

Thrilled to share our latest publication on DNA origami folding and functionalization! A fantastic collaboration with @kgoepfrich.bsky.social and Anabel Lostao teams. pubs.acs.org/doi/10.1021/... #DeDNAmers project 🧬with Jesús del Barrio @inmadivulga.bsky.social

submitted 27 days ago • 0 comments

How to achieve a high degree of functionalization on DNA origami in a cost-effective manner: pubs.acs.org/doi/10.1021/... It's been great to work with Siliva Hernandez-Ainsa again - twelve years after we first published on DNA origami together!

submitted 27 days ago • 1 comment

Looking for an awesome scientist who would like to become our neighbour. Application deadline coming up. Please share!

submitted 41 days ago • 0 comments

Overjoyed and honestly relieved to share a Chem Rev magnum opus from Brian Chen & Julia Li titled Synthetic Lipid Biology! In it, we organize efforts across numerous fields to create, manipulate, and analyze lipids and biomembranes. Check it out! doi.org/10.1021/acs.... #lipidtime #chemsky #chembio

submitted 41 days ago • 8 comments

Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology www.biorxiv.org/content/10.1...

submitted 62 days ago • 6 comments

We have an open professorship in #synbio / biological engineering in Heidelberg! jobs.zeit.de/jobs/full-pr... Check it out!

submitted 69 days ago • 0 comments

Just over a year ago, we launched the Seattle Hub for Synthetic Biology with @chanzuckerberg.bsky.social and @uwmedicine.bsky.social. #SeaSynBio is focused on developing tech that could spawn tools that observe cells and intervene to treat disease in real time. 🔗 alleninstitute.org/division/sea...

submitted 72 days ago • 1 comment

Agreed. Awesome work @jamessaenz.bsky.social One of these papers that leave you wonder "why has nobody asked this before". A very profound insight!

submitted 79 days ago • 1 comment

You can still submit articles for the collection "Nanopore applications beyond DNA sequencing" before January 24! www.nature.com/collections/... #nanopore

submitted 80 days ago • 0 comments

Thank you @alleninstitute.bsky.social for sharing our excitement for active membranes and for supporting our research!

submitted 82 days ago • 1 comment

Sweet summer news (so a bit old...) but our paper about a DNA nanostructure that activates cytotoxicity in tumor microenvironments is (still) out! - A cancer killing nanorobot. www.nature.com/articles/s41...

submitted 90 days ago • 1 comment

It was great fun to contribute to this review - a guide towards more effective, affordable, and robust immunotherapies - grateful for the energy and creativity of @kgoepfrich.bsky.social and this new research field taking off @researchlifesci.bsky.social.

submitted 90 days ago • 1 comment

My latest article is out! 1000 artificial cells synchronize in 2D and collective behavior emerges! #microfluidics #artificialcells #syntheticcells #cellfreeexpression doi.org/10.1038/s414...

submitted 91 days ago • 2 comments

Are you working in DNA/RNA nanotech? Add your name to the list!

submitted 90 days ago • 0 comments

So excited that @kakape.bsky.social will join us aa a visiting professor at Heidelberg. Looking forward to discuss about science communication in the context of synthetic biology and bottom-up engineering strategies to prevent & treat infections.

submitted 90 days ago • 0 comments

Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados! Feel free to share, add and distribute, so we can come together again! 😍 go.bsky.app/AEeXh86

submitted 100 days ago • 71 comments

Large-scale collective motion of epithelial cells not as a fluid, but as a polar elastic solid. Our new study posted on Biorxiv: www.biorxiv.org/content/10.1...

submitted 95 days ago • 2 comments

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas. www.embl.org/about/info/c...

submitted 96 days ago • 4 comments

I haven't seen a nucleic acids starter pack yet, so I started one! Please reach out if I missed you! go.bsky.app/NxKgUY5

submitted 98 days ago • 15 comments

Synthetic genomes for synthetic cells: A large language model for the generation and interpretation of genomic sequences https://www.science.org/doi/10.1126/science.ado9336 I shared some thoughts with @Tagesspiegel (in German):...

submitted 101 days ago • 1 comment

We did it (thanks to many helping hands)! Ready to bring our brandnew labspace @UniHeidelberg to life. Thanks @mpi_mr_hd for hosting us for the past 5 years, I could not think of a more friendly place to start a group. And thanks to @ZmbhH for the new home - now also physically.

submitted 117 days ago • 0 comments

Origami + Genome engineering = PICasSO! Best of luck to the @UniHeidelberg @iGEM team. Find out more about PICasSO here: https://video.igem.org/w/9115492c-4068-4d7b-9c74-9d8425c5f656

submitted 135 days ago • 0 comments

Happy to share our DNA microbeads as a tool for #organoid research @NatureNano - hope the community finds it useful to create light-controlled morphogen gradients in organoids https://rdcu.be/dTpfA Congrats @AftingCassian @ToWalther and thanks @WittbrodtLab!

submitted 168 days ago • 1 comment

What happens when you apply design principles from bottom-up synthetic biology to immunology? In Heidelberg and together with @FrischknechtLab @platten_michael & Oliver Fackler we compiled the prospects of bottom-up synthetic immunology @NatureNano https://rdcu.be/dR0r0

submitted 181 days ago • 0 comments

Thank you very much @esandersen Brigitte Städler @zelikin & Julian Valero Moreno et al for hosting us so we'll @iNANO_AarhusUni! @NehaPKamat

submitted 191 days ago • 0 comments

Biopriniting GUVs: https://pubs.acs.org/doi/10.1021/acssynbio.4c00137 Congrats Daniela Duarte Campos @ToWalther et al and thanks for the nice collaboration!

submitted 217 days ago • 0 comments

Last year we met with about 60 scientists for 2 weeks to discuss what it means to synthesize life. Here is the summary of our discussion: https://chemrxiv.org/engage/chemrxiv/article-details/668b9aaf01103d79c55e9fab We hope it represents diverse views and serves as a roadmap towards...

submitted 224 days ago • 1 comment

Congratulations to @maiptran21 for winning the poster prize at #FDN2024 for her work on RNA origami. The group is proud of you🙌Thanks to the FDN crowd!

submitted 240 days ago • 0 comments

Why are we so exited about RNA origami? It could be a unique intermediate between DNA origami and proteins for the construction of synthetic cellular hardware. We design and encode an RNA cytoskeleton in synthetic cells: https://www.biorxiv.org/content/10.1101/2024.06.12.598448v1...

submitted 255 days ago • 1 comment

If you are at #FNANO24, @majaillig and @floppleton are there and can tell you more about us 😊

submitted 305 days ago • 0 comments

We are looking for two #postdocs to join us: 1) @ERC_Research funded position in the context of RNA origami, cryoEM, synthetic cells, directed evolution; 2) A position in the excellence cluster @Cluster3DMM2O at the interface of chemistry & biology. Please share and get in touch!

submitted 306 days ago • 0 comments

We have 12 PhD positions in a doctoral training network on synthetic cells in labs across Europe. Get in touch! https://euraxess.ec.europa.eu/jobs/214286

submitted 319 days ago • 0 comments

@ToWalther presenting our DNA microbeads that he used to generate morphogen gradients in organoids together with @AftingCassian @WittbrodtLab 🤩 @Cluster3DMM2O

submitted 321 days ago • 0 comments

A shoutout to the bioprinting community: Commonly used photoresist molecules permeate accross cellular membranes. For guidance on which ones to use, check out our new paper @AdvSciNews: https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202315731

submitted 328 days ago • 1 comment