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kurianlab.bsky.social
RNA biology of embryonic development and disease #heart #ribosome #translational_control #RBP #splicing @UK_Frankfurt Alum:@salkinstitute @UcSandiego https://kurianlab.com/
388 posts 2,171 followers 935 following
Prolific Poster

#biosciencefacjobs

Nature research paper: Nerve-to-cancer transfer of mitochondria during cancer metastasis https://go.nature.com/46c474I

Stop the doom scrolling! A new 🗞️ from my lab, describing one of our flagship projects of many years we are super excited to share: "Inducible formation of fusion transcripts upregulates haploinsufficient CHD2 gene expression". A 🧵 biorxiv.org/content/earl...

www.science.org/doi/10.1126/...

Key breakthrough www.cell.com/cell/fulltex...

The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil

@igorulitsky.bsky.social ?

www.cell.com/cell/abstrac...

Alphagenome is out storage.googleapis.com/deepmind-med...

www.cell.com/cell-metabol...

🚨 Check out the latest from @trono-lab.bsky.social showing how evolutionarily young transcription factors contribute to human cell cycle regulation! Brilliant work led by Romain Forey and Cyril Pulver, now published in Cell Genomics. Check it out ! www.cell.com/cell-genomic...

Excited to share our review in Nature Reviews Genetics on cell-type deconvolution! "Cell-type deconvolution methods for spatial transcriptomics" 🔗 nature.com/articles/s41... 📖 Free access: rdcu.be/el0Ka

🥰 Self-supervised, label-free 3D cell imaging is here Congrats to Cyril on this very cool first, first author publication 🏆! This started when he was a bachelor's student (and he's now completing his masters!). And many thanks to my other awesome co-authors🙏 elifesciences.org/articles/99848

www.cell.com/cell-reports...

Dual SORT LNPs for multi-organ base editing go.nature.com/3HC9EHt

#microsky Throwing a spotlight on genomic dark matter: The power and potential of transposon-insertion sequencing - Journal of Biological Chemistry www.jbc.org/article/S002...

Extremely honored to receive this prize from @socdevbio.bsky.social, which recognizes not only my love for developmental biology, but the extremely online I am 🧪 (protect science, protect people, viva la dev bio!)

'The death occurred as private companies with little to no oversight are increasingly tasked with transporting more immigration detainees across the US, in pursuit of the Trump administration’s recently-announced target of arresting 3,000 people a day.' www.theguardian.com/us-news/2025...

Yup. I said what I said. Most people in the US don't even know what their own military looks like. 🤷🏿‍♂️ The ridiculousness of trying to use Marines for ICE raids in California, when so many Marines are Hispanic people from California that signed their very lives on the line for their family's papers.

@mads100tist.bsky.social calling attention to the awesomeness of #zebrafish #devbio and community. #SDB

Thrilled to see my postdoc work at Adelman Lab @hms-bcmp.bsky.social on Integrator(INT) now out @cp-cell.bsky.social. We found that INT deficiency allows immature+unlicensed RNAPII to precociously enter genes. This immature RNAPII can transcribe short genes but terminates prematurely in long genes:

This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u A short thread follows 1/n

I’m so honored to be selected as both a 2025 McKnight Scholar and 2025 HHMI Freeman Hrabowski Scholar. And I couldn’t be prouder to share these honors with awesome @ucdavis.bsky.social colleagues 💙💛💙💛 health.ucdavis.edu/news/headlin...

github.com/dincarnato/R... From @incarnatolab.bsky.social

@akispapantonis.bsky.social making Transciption factories great again

www.eventbrite.de/e/how-to-app...

I spoke with Jade Hindmon, host of @kpbssandiego.bsky.social Midday Edition, about the consequences of the current administration’s cuts to science funding. Please share to help spread the word and raise awareness. www.kpbs.org/podcasts/kpb...

Congratulations @stanford-chemh.bsky.social Institute Scholar @cobarnes27.bsky.social on being named a 2025 Freeman Hrabowski Scholar @hhmi.org 🎉 🍾 www.hhmi.org/programs/fre...

Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling non‑invasive in‑vivo imaging from molecules to organisms, is out. MOSAIC captures everything from subcellular dynamics to neural activity in live mice. www.biorxiv.org/content/10.1...

Congratulations to our own Lucas Farnung @lucas.farnunglab.com who has been named as one of 30 Freeman Hrabowski Scholars for 2025 by the Howard Hughes Medical Institute (HHMI). So well deserved deserved !! www.hhmi.org/programs/fre...

New Skeetorial time! 🦋 A new preprint led by Dr. #MinhooKim, where we present the characterization of #mouse models of #menopause using a combination of histology, endocrine measures, single-cell #transcriptomics, and #RNAscope validation! #GeroSky 🧪🖥️🧬 A 🧵 1/9 www.biorxiv.org/content/10.1...

My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy. Details found here👇 www.queensu.ca/grad-postdoc...

These r very sad days for me & colleagues @WeizmannScience & many civilians in our region. Yet, i am also stoked to be the 2025 recipient of the Nakasone Award by the Human Frontiers - HFSP. I would have never imagined in my wildest dreams to be on such a list. Tnx! www.hfsp.org/hfsp-nakason...

New preprint from Daniel Du @fitzpatricklab.bsky.social shows #femtosecond light pulses can lens electron beams, promising higher contrast in #cryoET and better aberration correction in #cryoEM tinyurl.com/257sw7j9 Experiments made possible by support from @cziscience.bsky.social #ImagingTheFuture

In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput approach to measure nuclear condensate formation, and applied it to ~14,000 IDPs to find out! rdcu.be/eq975

Our latest work: The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis: Cell www.cell.com/cell/fulltex...

Last February, I led a proposal submission that encompassed six months, hundreds of hours, four institutions, a massive team, and and 256 pages. NSF just informed us that the entire Biology Integration Institute program was archived and our proposal would not even be reviewed. With a form email.

www.biorxiv.org/content/10.1...

www.biorxiv.org/content/10.1...

www.science.org/doi/10.1126/...

training.institut-curie.org/courses/deve...

Stephen Miller’s uncle has something to say: “I have watched with dismay and increasing horror as my nephew, an educated man who is well aware of his heritage, has become the architect of immigration policies that repudiate the very foundation of our family’s life” www.politico.com/magazine/sto...

The stupidest people are in charge because we couldn’t prosecute a political crime because it would look too political.

Histo-LCM-Hi-C reveals the 3D chromatin conformation of spatially localized rare cells in tissues at high resolution https://www.biorxiv.org/content/10.1101/2025.06.10.658807v1

'Thirty years later, I watch the rise of the far right in Europe and America in astonishment. It is as if a stone-cold corpse from my country’s past has arisen from the dead. Whenever I open the newspapers or turn on the TV, the déjà vu is uncanny.' www.ft.com/content/c600...