lammerdinglab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Our first 2025 paper! We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer. Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏 www.nature.com/articles/s41...

submitted 49 days ago • 3 comments

In their Review, Julien Morival, Anna Hazelwood and Jan Lammerding @lammerdinglab.bsky.social discuss new insights and technological advances in understanding nuclear mechanotransduction. journals.biologists.com/jcs/article/...

submitted 7 days ago • 1 comment

Interested in nuclear mechanobiology, and how advanced genomic tools can shed light on how the cell nucleus might sense mechanical forces? Read our latest review by excellent Julien Morival and Anna Hazelwood, now published @jcellsci.bsky.social: journals.biologists.com/jcs/article-...

submitted 9 days ago • 0 comments

What a surreal experience. #standupforscience2025 is the honor of my lifetime. I am just speechless. So grateful to the hundreds of volunteers, thousands of attendees, and countless inspirational speakers across rallies. My heart is full. @standupforscience.bsky.social 1/2

submitted 12 days ago • 17 comments

Extending my grant update this morning. Here are data limited to new and competitive renewal applications. The Pause is dead, Long live the Pause...

submitted 18 days ago • 13 comments

Great opportunity: applications are open for the Weill Institute Emerging Scholars Symposium @Cornell! Senior PhD students and postdocs interested in networking & presenting their work in cell & molecular biology should apply by Apr 14. wicmb.cornell.edu/emerging-schol… Please repost!

submitted 23 days ago • 0 comments

Thank you @nplb.bsky.social for speaking out in defense of patients, the US economy and our citizenship. Encouraged to see biopharma and investors among patients, health care providers, scientists and policy makers. www.nopatientleftbehind.org/defending-th...

submitted 25 days ago • 0 comments

We have to fight now for research that we know benefits all of humanity, we have to stand up for our colleagues at the NIH, we can’t lie down and take it, we stand against this madness #standupforscience2025

submitted 32 days ago • 0 comments

Executive wants to frame the NIH indirects cut as $4B in savings. But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.

submitted 40 days ago • 74 comments

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

submitted 40 days ago • 269 comments

This is catastrophic for US research universities as it ignores the real cost of doing research. The US academic-gov’t partnership forged post-WWII is the greatest creator of knowledge in history and is critical to US economic and technological competitiveness.

submitted 40 days ago • 3 comments

A Primer on Indirect Cost Rates

submitted 40 days ago • 15 comments

Research universities are often the largest employers in their region. They are often the primary health care providers to communities. This funding shift will not only reduce US research leadership, it will put working people out of work and reduce healthcare access.

submitted 40 days ago • 105 comments

Terribly sad to learn of Dr. Michael Sheetz's passing. Mike was a foundational figure in mechanobiology and a strong advocate for the field. He also made us all better by holding himself and others to the highest intellectual standards. Condolences and best wishes to Mike's family and friends.

submitted 45 days ago • 1 comment

The NIH diversity supplement pages have all been pulled down. What is a diversity supplement and why should the public care? A diversity supplement is funding to help diversify the research workforce. You may be wondering, “so what?”. Let me explain. www.nigms.nih.gov/Pages/PageNo...

submitted 53 days ago • 9 comments

The dark side of fluorescent protein tagging: the impact of protein tags on biomolecular condensation www.biorxiv.org/content/10.1...

submitted 114 days ago • 10 comments

PhD students: it’s a waste to just try to impress your committee at the meeting. Bring them problems, ask for suggestions, and generally think of it as a session in which new ideas can emerge.

submitted 74 days ago • 1 comment

Our lab has multiple open positions for post-docs to study the regulation and function of cytoplasm mechanics during embryo development. Details below 👇👇 Please Repost !!! @ijmonod.bsky.social @cnrs.bsky.social

submitted 75 days ago • 0 comments

Exciting work by Martin Beck’s group @mpibp.bsky.social providing further evidence for nuclear pores responding to mechanical stress. The work includes some nice modeling estimating the fluid flow across nuclear pores as a function of (osmotic) pressure. www.cell.com/molecular-ce...

submitted 80 days ago • 1 comment

My latest Research Highlight is now online @natrevmcb.bsky.social! The Brangwynne lab uncovers how chromatin heterogeneity influences condensate formation during #CellMigration, revealing intriguing insights into nuclear mechanics. 🔗 go.nature.com/3ZpwGH7 OG Paper: go.nature.com/3Baxpnn

submitted 104 days ago • 0 comments

Are you interested in learning about how engineering and physics can be applied to study the motions of #plants, #invertebrates, and #animals? Here's a non-exhaustive list of Comparative Biomechanists to get started! 🦋 🐟 🦎 🌿 🧪 go.bsky.app/HvHFgvB Apologies for any that I may have been missed.

submitted 110 days ago • 9 comments

#FluorescenceFriday Witness the magic: Our homebrewed mStayGold live-cell imaging probe for enhancer nucleosomes at 300ms temporal resolution Designed and imaged by this PI (yep, me 😂). Hot damn, these dynamics are mind-blowing—like watching a realtime chromatin dance #Microscopy #ChromatinArtistry

submitted 110 days ago • 4 comments

Just because its fun~ This is one of my favorite videos I've taken in my PhD! Here is 60x imaging of neutrophils swarming to attack yeast targets in blue :)

submitted 133 days ago • 4 comments

The 2024-2025 BME TT Faculty jobs list has 122 positions. #FacultySearch #BME #BMEJobsList Add a job: forms.gle/HPzAKkS1x44t... Jobs list: ericaprattlab.com/bme_jobs_list/

submitted 117 days ago • 1 comment

@anjalibhagirath.bsky.social Anjali, I just noticed the picture of Schloss Nordkirchen on your profile. Nice to see a glimpse of home here!

submitted 117 days ago • 0 comments

For #FluorescenceFriday, a found an old video of MDA-MB-231 cells in a dense collagen matrix dividing, acquired on a lattice lightsheet microscope at the @aicjanelia.bsky.social. Mitotic chromosomes are fun to watch! This was just a quick test video, hence the limited but still impressive quality.

submitted 117 days ago • 1 comment

Time to shine for intermediate filaments! An optogenetic vimentin perturbation strategy reveals its role for ER and mitochondria positioning (but no effect on actin or microtubules patterns) @joycemeiri.bsky.social www.biorxiv.org/content/10.1...

submitted 118 days ago • 1 comment

🚀 Excited to share that my postdoc work with @adernburg.bsky.social on a Piezo-dependent meiotic checkpoint in C. elegans has just been published in Science doi.org/10.1126/scie... Here's a summary thread, or a “Skydive” (coined by @harmitmalik.bsky.social‬), of the key findings in this work 🧵⬇️1/10

submitted 117 days ago • 6 comments

👋Hello #mechanobiology community! Next year we are organizing the CellMech conference in Leuven! We will soon be announcing (super amazing) invited speakers, registration deadlines, etc I'll try to keep the🦋community updated, but best is to subscribe to the mailing list 📧👇 cellmech2025.org

submitted 119 days ago • 0 comments

Meet the amazing people behind our research, a fantastic team of scientists and engineers from various disciplines and countries, united in their interest in #mechanobiology and its application to basic science and disease. Plus a huge passion for working together and enriching the community.

submitted 118 days ago • 0 comments

Find a friend to talk science with. Or assemble a peer group. Exchange ideas and critiques. I’ve always believed this is critical to doing good science.

submitted 118 days ago • 0 comments

I didn't find a specific mechanotransduction starter pack, so I open one myself😊. There are still a lot of people to be added, but it's late, so please drop me a message or post here to nominate yourself for the Mechanotransduction community. go.bsky.app/2PXf5SC

submitted 119 days ago • 39 comments

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas. www.embl.org/about/info/c...

submitted 119 days ago • 4 comments

Q: What's wrong with these plots? A: Pooling cell-level measurements across multiple runs conceals experimental reproducibility. Read more in JCB (with @fritzlaylin.bsky.social @katrinavelle.bsky.social & Dyche Mullins): rupress.org/jcb/article/...

submitted 121 days ago • 10 comments

A late entry for #FluorescenceFriday or an early post for #MicroscopyMonday, reposting a movie of a breast cancer cell migrating through a small microfluidic constriction by contracting its rear cortex. You can find the full story at journals.biologists.com/jcs/article-...

submitted 124 days ago • 0 comments

Sharing this on behalf of the Connecting Intermediate Filaments community: Tune in next Wednesday November 20, for our first #ConnectingIFs seminar of the season 2024-2025, with Prof. Carsten Grashoff, University of Munster (www.uni-muenster.de/Biologie.IMZ...) @ 10.00 AM EST, 16:00 CET

submitted 124 days ago • 0 comments