lebrunlab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Cryptosporidium modifies intestinal microvilli through an exported virulence factor!! Phenomenal work from the newly DR’ed Elena Rodrigues www.biorxiv.org/content/10.1...

submitted 1 day ago • 5 comments

📅 Save the Date! The EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by @ParaFrap will take place on October 5-8, 2025, at Les Embiez Island. Stay updated on registration opening —enter your email here: coming-soon.embo.org/w25-83 #Science #Parasite

submitted 2 days ago • 0 comments

I wish I could send all of you out there a hug - witnessing second hand so much needless stress, uncertainty and suffering. I see you and I stand with you.

submitted 6 days ago • 0 comments

#PLOSPathogens: The #malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole dx.plos.org/10.1371/jour... @plos.org ParaFrap Teams: @lebrunlab.bsky.social @lavazeclab.bsky.social

submitted 18 days ago • 0 comments

Stoked to see the latest research from our lab now out in @plosbiology.org! Check it out to learn more about lineage-specific adaptations in the cytosolic iron-sulfur assembly pathway in Apicomplexa. journals.plos.org/plosbiology/...

submitted 21 days ago • 0 comments

Iron-sulfur proteins require specialized assembly pathways. @s-besteiro.bsky.social &co show that the plastid-derived protein HCF101 functions in the cytosolic Fe-S assembly pathway in #Toxoplasma and is crucial for #parasite viability 🧪 @plosbiology.org plos.io/3EFKKoQ

submitted 20 days ago • 0 comments

Do you work on parasites and reside in an LMIC? Consider applying for a 2025 MPM LMIC award. The deadline is March 3rd, 2025—details on the website. www.parasitesrule.com/mpm-xxxvi/tr...

submitted 23 days ago • 0 comments

📣 ParaFrap Webinar: Gretchen DIFFENDALL (Team A.Scherf @pasteur.fr): Metabolomics Identifies a Natural Host Cytoadhesion Inhibitor in Asymptomatic #Malaria Cases @parafrap.bsky.social Chairperson: Antoine CLAESSENS @ant1-claessens.bsky.social 🗓️ Thursday, February 13, 3pm CET 🎟️ bit.ly/ParaFrapWeb

submitted 23 days ago • 0 comments

Global Parasitology Seminar next Monday: Ira Blader on Toxoplasma & oxygen. 2/10/25 12 pm EST in person & zoom. ⁦‪@TrendsParasitol‬⁩ ⁦‪@BSPparasitology‬⁩ ⁦‪@parasitesrule‬⁩ ⁦‪@AmSocParasit‬⁩ ⁦‪@AS_Para‬⁩ ⁦‪@pennvet‬⁩ ⁦‪@SFParasitologie‬⁩ ⁦‪@CTEGD‬⁩

submitted 24 days ago • 0 comments

Register! womeninmalaria.es/wim-conferen...

submitted 30 days ago • 0 comments

The MPM XXXVI page is now live. Sept 14th to Sept 18th. More updates will be coming soon. Check it out on the parasitesrule.com website. Organized this year by Richarch McCulloch @rmc9z.bsky.social, Photini Sinnis, Marc-Jan Gubbels, Deepali Ravel & Omar Harb @omarharb.bsky.social

submitted 37 days ago • 0 comments

First Global Parasitology Seminar of 2025: Nathan Schmidt on Malaria & Microbiome. Monday 01/27 12 pm US EST. @womeninmalaria @BSPparasitology @FightingMalaria @AmSocParasit @UPenn_I3H @MBLBoP

submitted 35 days ago • 0 comments

I'm thrilled to announce our latest work is now published in Cell! Viruses encode numerous proteins that inhibit host defenses, but identifying immune-modulatory proteins among millions of viral sequences has been nearly impossible - until now! www.cell.com/cell/fulltex...

submitted 35 days ago • 6 comments

Remember learning that ribosomes are made of 1 large subunit RNA + 1 small subunit RNA? Well, some cells defy this rule, and the most extreme case is Toxoplasma which makes its mitoribosome from >50 RNA pieces! Wanna know how? Read below

submitted 38 days ago • 14 comments

Delighted to share our study on a major Toxoplasma virulence factor that prevents lytic host cell death. Many thanks to @parafrap.bsky.social for support, constructive reviews and all labs involved: Melissa Lodoen, Hiba El Hajj, @gissotlab.bsky.social, Karine Le Roch Link : rdcu.be/d6m3G

submitted 42 days ago • 1 comment

Have you finished your #PhD and are interested in exploring how #parasites cross the vasculature to colonize tissues? Do you fancy catching some #waves in the Atlantic? Or eating grilled fish by the beach? Join us in #Lisbon at GIMM, where science meets quality of life. @parasitesrule.bsky.social

submitted 45 days ago • 1 comment

Hey Bluesky :) Last chance to apply for AFRIBOP 2025 hosted by the University of Glasgow, KEMRI Wellcome Trust, and the Malawi Liverpool Wellcome Trust! Fantastic opportunity - pls share with anyone you think may be interested! Apply here : shorturl.at/2sRFS

submitted 45 days ago • 0 comments

Cascading expression of ApiAP2 transcription factors controls daughter cell assembly in Toxoplasma gondii journals.plos.org/plospathogen...

submitted 47 days ago • 0 comments

📢🦟 Sign up for #EMBLMalaria and join us in this crucial endeavour to understand the biology of the #malaria parasite and to advance global health 🌍⚕️ 👉🏻 s.embl.org/bmp25-01-bl 📅 20 – 22 May 2025 📍 EMBL Heidelberg and Virtual 📝 Submit your abstract by 25 Feb!

submitted 48 days ago • 1 comment

Don’t miss Yi-Wei summarizing his amazing work as an Assistant Professor. This will be both, great science and a lot of fun!

submitted 51 days ago • 0 comments

www.nature.com/articles/s41...

submitted 52 days ago • 0 comments

Cytoskeleton rearrangements promote formation of a giant structure called a GUVac that stops cells from dying when they become detached from the extracellular matrix. 🔗 https://elifesciences.org/articles/104942?utm_source=bluesky&utm_medium=social&utm_campaign=organic_insights

submitted 56 days ago • 0 comments

rdcu.be/d5o3U it's out!!

submitted 56 days ago • 4 comments

The best way to start 2025: our latest work is out in #PLOSPathogens. It discusses ApiAP2 transcription factors and daughter cell assembly in T. gondii. A work spearheaded by @be-maanasa.bsky.social with the contribution of @mudiyamv.bsky.social dx.plos.org/10.1371/jour...

submitted 57 days ago • 0 comments

Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein | Science

submitted 56 days ago • 0 comments

🦟🌍 Join us for the 21st edition of #EMBLMalaria as we strengthen partnerships, share insights, and drive innovations to combat malaria's toll and advance global health. 📅 20 – 22 May 2025 📍 EMBL Heidelberg and Virtual 📝 Submit abstract by 25 Feb 👉🏻 s.embl.org/bmp25-01-bl #malaria #epidemiology

submitted 73 days ago • 0 comments

We are very excited to announce a new @events.embl.org conference with a general focus on all infections with the goal to foster discussions across researchers working on multiple pathogens. We couldn't find a conference as such in Europe, so we decided to organize it 😊 www.embl.org/about/info/c...

submitted 70 days ago • 0 comments

Fancy some CRISPR screening? We are looking for an enthusiastic #posdoc to join us to investigate #Toxoplasma host-path interactions in different hosts. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

submitted 70 days ago • 0 comments

Malaria – the world’s most deadly vector-borne disease – is particularly sensitive to variations in climate and weather. (...) Investment in climate-resilient health systems and paradigm-shifting new tools is critical to accelerate progress towards eradication. malariaatlas.org/project-reso...

submitted 75 days ago • 0 comments

Xmas lunch with the lab, glad to work with such a nice and talented bunch of scientists. @lebrunlab @martacova

submitted 76 days ago • 0 comments

A New Approach to Predicting Malaria Drug Resistance today.ucsd.edu/story/a-new-... Their "work reveals how to distinguish phenotype-driving variants from passengers, a key challenge of forward genetics approaches."

submitted 78 days ago • 1 comment

🚨🚨🚨 L'@ipbstoulouse.bsky.social est laboratoire d'accueil pour 4 postes de MCU en biochimie, biologie moléculaire, génétique et microbiologie qui vont ouvrir au concours en 2025 à l'Université de Toulouse #Emploi #Université #Maitredeconférences 👇

submitted 80 days ago • 2 comments

Controlling the genes of a parasite. https://buff.ly/4g2ujRr

submitted 81 days ago • 0 comments

Delighted to share our first manuscript on @bsky.app on a novel SUN1-ALLAN complex in Plasmodium MTOC and NE organization. Many thanks @zeeshanm.bsky.social; @eelcotromer.bsky.social; @ryanase.bsky.social ; Tony; Sarah; David F; Karine; Igor; Cyrille; Declan. Link: www.biorxiv.org/content/10.1...

submitted 83 days ago • 1 comment

Have you ever wondered how knocking out every single gene in the human genome, one by one, might affect your intracellular pathogen of interest? We did, & boy was it a wild ride! Happy to share our preprint discovering the essential host genome for Cryptosporidium - www.biorxiv.org/content/10.1...

submitted 83 days ago • 4 comments