legidoquigley.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

The analogy of omics data normalization and cooking: some processing is usually necessary, overcooking makes it bland, highly over-processed foods are unhealthy, and the quality of the ingredients matters.

submitted 11 hours ago • 1 comment

5-drug precision prescribing for people with type 2 diabetes is here Our model for optimising glucose lowering therapy using low-cost routine clinical features published in the Lancet today Paper: thelancet.com/journals/lan... Try the web tool here: diabetesgenes.org/t2-treatment/

submitted 1 day ago • 2 comments

recording a podcast on Friday and the one question I know in advance is "what's your favorite molecule and why?" #metabolomics #lipidomics #proteomics and now choose one from 10.000 😅

submitted 2 days ago • 0 comments

Scientists have developed an AI-powered tool that detects 64% of brain abnormalities linked to epilepsy that human radiologists miss. MELD Graph is an AI tool that could drastically change the care for 4 million patients. @kingslsm.bsky.social @ucl.ac.uk. www.kcl.ac.uk/news/kings-n...

submitted 2 days ago • 1 comment

“There’s going to be a missing age class of researchers that will reverberate for years.” scim.ag/3ERRLDo

submitted 3 days ago • 72 comments

beautiful, are these their cousins from London?

submitted 3 days ago • 1 comment

🔥 Finally!! Starmer ready to offer Youth Mobility Scheme. 🙌🙌🙌

submitted 6 days ago • 148 comments

Metabolomic insight into the link of intermuscular fat with cognitive performance: the Health ABC Study #Geroscience #MassSpec link.springer.com/article/10.1...

submitted 6 days ago • 0 comments

Sweet, my collaborators managed to submit to ARPAH, and to add me as a collab, considering the difficult times submitting a grant is a win 4/10

submitted 6 days ago • 0 comments

I've been developing a semantic search tool that covers not just bioRxiv and medRxiv, but the entire PubMed database. This means you can search across a massive collection of biomedical research using keywords, questions, hypotheses, or even full abstracts. Try it out: mssearch.xyz

submitted 11 days ago • 35 comments

Looking forward to speaking in #cimm2025 & learning from fellow speakers, the program is amazing www.linkedin.com/posts/cmi-uc...

submitted 10 days ago • 0 comments

There doesn't seem to be much we can do to support our fellow scientists in the US but we can at least lobby for this important signal to the world

submitted 13 days ago • 1 comment

🚨Amidst all the uncertainty at NIH Welcome Leap just launched an important new $50M program in Women’s Health👩🏻‍🔬🧠 CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/ Note: full indirects! Please share widely to support women’s health 🙏🏼

submitted 13 days ago • 17 comments

Glucose, not insulin, associated w/ AD risk “…interesting results in how diabetes–related markers are causally related to brain health albeit the precise mechanisms through which postprandial hyperglycaemia increases AD risk and higher insulin preserves brain volumes warrant further research.”

submitted 14 days ago • 0 comments

BREAKING: NIH admits funding freeze is illegal, will resume issuing grants open.substack.com/pub/populari...

submitted 14 days ago • 135 comments

Monthly 10 pm calls for 3 years on a meeting with Alzheimer's investigators across the globe, finally a big grant through phase 2 in US but with the chaos is too complicated to add international PIs. UK & Canada PIs so far giving letters of support the same 🙌🏻. Would have been my grant 4.

submitted 14 days ago • 1 comment

Worth listening to Bill Gates on the biggest world challenges in this lighthearted podcast, mentions so much of our lab's research themes, Alzheimer's, obesity & the microbiome, AI for better healthcare 🦾 podcasts.apple.com/gb/podcast/s...

submitted 15 days ago • 0 comments

#WomenInScience day, unfortunately this scissors pipeline shows that many women leave. How can we support women? we need to appreciate their skills, knowledge, work & leadership style. ✂️ graph from Australia, #WomenInSTEM #ScienceForAll

submitted 16 days ago • 0 comments

Happy International Day of Women & Girls in Science! Today we're showcasing Jean Purdy's pivotal role in IVF development. Madelin, one of our Archivists, takes a look at one of Purdy's letters and explores what it shows about her groundbreaking research. 🎶Bensound #womeninscience #WomeninSTEM

submitted 16 days ago • 0 comments

Today, for International Day of Women & Girls in Science, I would like to pay tribute to my PhD supervisor Jo Peters. It's her funeral this afternoon- you can read a lovely tribute to her here www.har.mrc.ac.uk/news/profess... It's hard to overstate how supportive and kind she was 💔

submitted 16 days ago • 0 comments

Happy International Day of Women and Girls in Science 🧪👩‍🔬

submitted 16 days ago • 28 comments

Decimating the NSF would be an act of violence against USA competitiveness in science, technology and innovation. Have any of these people seen Shanghai lately? arstechnica.com/science/2025...

submitted 20 days ago • 7 comments

The clinical research charity, for which I'm a board member, designed a new call for 4th year PhD funds. I think that's such a brilliant idea, funds can do so much good at this point. What would you fund in the #dementia research space?

submitted 20 days ago • 0 comments

How much have we advanced in leadership for #WomeninSTEM and women in healthcare? I wonder how many men know about these biases onlinelibrary.wiley.com/doi/epdf/10....

submitted 21 days ago • 0 comments

Taking non-invasive glucose tracking to the next level, using Raman spectroscopy, without any needles www.nature.com/articles/s42...

submitted 22 days ago • 11 comments

My collaborator in Italy is submitting an EU Network grant to find diagnosis of neuro disease with 2 hospitals, 3 unis, 2 small companies, my grant count continues... 3 out of 10

submitted 22 days ago • 0 comments

Do you know any free online courses on statistics applied to clinical data, univariate, multivariate and maybe linear mixed models for longitudinal data? if they use R or python to demo & visualize even better

submitted 23 days ago • 7 comments

I did a list of #WomeinSTEM working in #metabolomics & #lipidomics and #datascience please join or share with others, use it for conferences, media & networking, mentoring, supporting, anything that helps, 300+ women have joined docs.google.com/document/u/0...

submitted 27 days ago • 0 comments

“If the freeze is not stopped, I might lose my house." Some NSF-funded postdocs are having trouble paying rent and credit card bills because their salaries were paused this week, even though the federal funding freeze memo was rescinded. www.statnews.com/2025/01/30/t...

submitted 27 days ago • 289 comments

sorry to hear, I'm in denial with one of our #massspec instruments, its failure due to sabotage is too depressive for me to process, for now the instrument doesn't exist, until I can do something about it.

submitted 27 days ago • 2 comments

Riccardo Marioni showing his EpiScore results in the Generation Scotland, the cohort that we are also lucky to study for lipidomics & multiomics

submitted 29 days ago • 0 comments

AI agents to revise science, three agents that discuss from the PubMed publications 👀 who is famous reviewer 3? the angel who finds faults in everything 😇

submitted 29 days ago • 0 comments

interesting talk using 30 million publications in PubMed mined by an LLM AI assistant for more reliable information by Janet Piñeiro it also gives an evidence score & gives the publication code

submitted 29 days ago • 0 comments

Now a talk about the ugly history of genetics 😱 although those two guys look familiar

submitted 29 days ago • 0 comments

so many people in London interested in omics, I can't hear anything, this talk about precision nutrition by Tim Spector from Kings College my uni

submitted 29 days ago • 1 comment

Dear America Maybe you need an Independent SAGE right now? www.nature.com/articles/s41...

submitted 33 days ago • 17 comments

Welcome immigrants from X interested in science to the friendlier skies of @bsky.app, as documented by a new @nature.com survey (but you already knew that 😉) "Bluesky is much better for science. There is much less toxicity, misinformation, and distractions." www.nature.com/articles/d41...

submitted 34 days ago • 252 comments

Today the Trump admin abruptly and indefinitely terminated many of the activities of the National Institutes of Health, the $50B/year collection of agencies that power the US biotech and health ecosystems. Even if these orders were lifted tomorrow, the disruption would be enormous. Why care? 🧵

submitted 35 days ago • 20 comments