lgbacteria.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

I just posted "Some Experiments Work, and Some Don't." It features this new paper from Paul Rainey's group, along with a failed experiment that Paul Sniegowski and I ran in the 1990s trying to test the same idea. telliamedrevisited.wordpress.com/2025/02/21/s...

submitted 2 days ago • 2 comments

➡️ NIH grants in '23 included $26B of direct costs and $9B of F&A = 26% of total costs or 35% of total direct costs. These are LOW overhead rates for any R&D-intensive industry. Academic biomedical research is an efficient bargain. ➡️ Every $1 of NIH support generates ~$2.50 of economic activity.

submitted 2 days ago • 0 comments

Two (!) perspective pieces published today involving people from our lab! @adelpanta.bsky.social on spatial patterning in microbial communities www.nature.com/articles/s41... and @salazarafra.bsky.social on microbial communities as evolutionary individuals www.sciencedirect.com/science/arti...

submitted 4 days ago • 1 comment

Experimental evolution of evolvability | Science www.science.org/doi/10.1126/...

submitted 3 days ago • 0 comments

New mechanism of gene transfer! With @tcostalab.bsky.social @imperialcollegeldn.bsky.social, we discovered that cf-PICIs form tail-less elements that, once released, spread among different bacterial species by hijacking tails from various phages. More exciting news soon! shorturl.at/kRJqE

submitted 12 days ago • 0 comments

All of this is true. The potential damage is almost unimaginable.

submitted 13 days ago • 1 comment

not paying indirect costs for research is like only paying the players in the Super Bowl. can't have a Super Bowl without coaches, referees, security, janitors, announcers, stadium staff, and a stadium - and you can't have research without supporting people and facilities

submitted 14 days ago • 19 comments

This paper has been a long time coming: We looked at the genomes of historical bacterial samples over a century to look for trends of antibiotic resistance genes, finding multiple instances of them in infections before the age of antibiotics, but an increase in both frequency and mobility after

submitted 37 days ago • 11 comments

People sometimes make fun of science that sounds stupid and random. Meanwhile, a study of lizard saliva turned into a peptide medication, which was turned into a diabetes medication, which was turned into a GLP1 weight loss drug, that just became the first therapy every approved for … sleep apnea

submitted 65 days ago • 380 comments

WHY do we have so many deadlines in early January? Why do Orgs in countries that overwhelmingly celebrate Christmas do this? These deadlines aren't natural phenomena - we are in control of this!! We don't we just... not? And let everyone have a genuine break? 🤔🙃

submitted 67 days ago • 8 comments

Check out this thread on the latest work from our lab, led by @emilykibby.bsky.social ! Here we used the power of computationally predicting protein-protein interactions to understand how a bacterial antiphage system senses infection.

submitted 67 days ago • 1 comment

It's time 🙃!! The soon-to-be-open Bomba-Warczak Lab at UPenn is HIRING postdocs! If you're interested in mitochondria, proteomics, neurons and/or oocytes, and want to join a young & vibrant lab in a vibrant city - apply 👉 www.bombawarczaklab.com/people/now-h... #TeamMassSpec #mitochondria

submitted 73 days ago • 3 comments

For every $1 of NIH funding generated approximately $2.64 of economic activity. For every $100 million of funding, the patents created generate an estimated $598 million in further R&D. NIH-funded patents represent significant advances and produce 20% more economic value than other patents.

submitted 78 days ago • 28 comments

Keeping your symbiosis genes on a plasmid is a smart move if you have multiple potential hosts. Here a gut bacterial symbiont, but same is true for N-fixing Rhizobia. www.science.org/doi/10.1126/...

submitted 79 days ago • 2 comments

To honour Abigail A. Salyers (1942-2013), who is considered as the mother of microbiome research, DSMZ researchers named the strain Streptomyces salyersiae (DSM 41770) after her. #WomenInScience #antibiotics #antibioticresistance #microbiome #microbiology

submitted 81 days ago • 1 comment

We're hiring a gnotobiotic mouse specialist! This person will maintain our germ-free mouse colony and manage gnotobiotic operations in the lab. phxc1b.rfer.us/STANFORDRn8Seh

submitted 80 days ago • 0 comments

First post on a lovely story from the lab that shows that Faecalibacterium prausnitzii can package its own genome in bite-size segments in phage-like capsids www.biorxiv.org/content/10.1...

submitted 90 days ago • 2 comments

Exciting times! Our latest preprint is now live 🤩! After nearly 16 yrs of running my lab, I truly believe this is one of the most significant contributions we've made. It offers fresh hypotheses about how pandemic Vibrio cholerae spreads globally. Let’s dive in!🧵..1/n www.biorxiv.org/content/10.1...

submitted 91 days ago • 4 comments

The Leading Edge Fellows starter pack is now up to 101 Leading Edge Fellows! If you haven't checked it out recently, there are lots of fabulous new postdocs and new PIs to follow!

submitted 90 days ago • 0 comments

Diversity-generating retroelements for the win!

submitted 96 days ago • 0 comments

Hi friends new and old! I study how microbes interact and evolve in complex communities like the human gut microbiome.🦠🧬💩 I'm thrilled to share that I'm starting a lab at UC Irvine in April 2025 and am recruiting at all levels - please spread the word! kxuelab.com More about my work below...🧵1/n

submitted 96 days ago • 22 comments

Hi everyone, I tried assembling a Microbiome & friends starter pack. 🦠🧫🔬 Still learning to use bluesky and might have missed you, let me know if you would like to be included. go.bsky.app/Fq36egy

submitted 128 days ago • 122 comments

Mobile Elements Starter Pack on BlueSky! Interested in plasmids, phages, ICEs, transposons, integrons, and all things accessory genome? Follow this curated list of researchers and labs doing exciting work in mobile elements.

submitted 106 days ago • 29 comments

This is the message we need to shout from the rooftops. It’s not about navel gazing, investment in science is one of the best ways to invest in the economy! And to keep us all safe.

submitted 100 days ago • 3 comments

Evidently you can use clearsky.app to see which lists you've been added to. Thanks to the hundreds of folks who added me to their starter packs! Super kind of you all. This website is full of surprises. What other features have you discovered?

submitted 102 days ago • 29 comments

📢The Zlitni Lab at UCSF is recruiting postdocs (experimental and computational) to join our team. We study microbial communication & quorum sensing in the human microbiome, and how these processes influence health and disease. To apply shorturl.at/erriN Please share widely!

submitted 123 days ago • 0 comments

About five years of work (and so many more threads to pull!). Just one snapshot of how our gut bacteria are evolving with our lifestyles.

submitted 300 days ago • 1 comment

The Accorsi Lab will open this Spring at UC Davis to study the development and regeneration of the Apple Snail visual system 🐌. We are hiring a tech to join us in creating a collaborative and inclusive environment and exploring cool biology! Apply here: recruit.ucdavis.edu/JPF06290

submitted 385 days ago • 1 comment

🔔New preprint! In which we explore the ecological consequences of plasmid-bacterial compensatory evolution using models and experiments. With Rosanna Wright, Jamie Wood, Mike Bottery, @brockhurstlab.bsky.social and others 🧫💫🦠 www.biorxiv.org/content/10.1...

submitted 405 days ago • 1 comment

Applications for the 2024 Leading Edge cohort are open! Due Feb 1. Leading Edge provides community, training, and visibility for postdocs pursuing academic careers. Year-round online career dev + in-person symposium at Janelia in June www.leadingedgesymposium.org/apply/

submitted 468 days ago • 0 comments

Can't say enough good things about this department, do apply!!

submitted 474 days ago • 0 comments