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lhinderling.bsky.social
tries to make microscopes smarter · bioimage analysis, optogenetics, ml, 3d printing, open science · phd student in cellular signalling dynamics @PertzLab
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PREPRINT OUT ✨ "hack" your microscope to work as a 3D printer! print micrometer sized features at cm scale. a method for easy and cheap microfabrication, with a focus on biological applications. THREAD ↓ www.biorxiv.org/content/10.1...

Hi folks! napari is officially on bsky now! 🥳 Let's hit the ground running with a reminder that all are welcome at our next (Atlantic) community meeting on Feb 12, 8:30am SFO / 11:30am NYC / 5:30pm Paris. Agenda and details here: hackmd.io/BXWDZ3i8Q6OA...

www.eventbrite.com/e/the-art-of... Attn Boston folk: I will be co-teaching a microscopy course at Artisans Asylum with Gary Valaskovic, a fellow Artisans member and expert in polarization/chemical microscopy. Crystals + plankton + optics + art + DIY modifications and more. Starts March 8. #sciart

Microscopy Nodes is now up on bioRxiv! 🚀 This is a Blender extension that seamlessly integrates and visualizes 3D microscopy data (TIF & @zarr.dev). High-quality volume rendering for anyone, in both EM and fluorescence, regardless of computational expertise! 🔬 www.biorxiv.org/content/10.1...

🎉 Zarr-Python 3 is here! 🎉 - Full support for Zarr v3 spec - Chunk-sharding for more efficient data storage - Major performance boosts with async I/O & parallel compression 💻 pip install --upgrade zarr 💻 conda install --channel conda-forge zarr Blog post: https://buff.ly/3C3OwYw

Biased but honest opinion: best microscopy course there is! 👍 🔬 👩‍🎓 Apply this month, join us late May and early April at CSHL!!!

I had a great time talking with @atinygreencell.bsky.social about my journey from doing my PhD in Brazil, and moving to U.S to continue my career :). Subscribe and support his channel if you can, he is doing a great job making science more accessible to everyone :) www.youtube.com/@ATinyGreenC...

Tears In Rain Episode 5 is live!!! I hung out with @daniellebeckman.bsky.social where she told us about her experiences as a student in Brazil that shaped her current interests in viruses inside the human brain. I hope you enjoy! Please like and subscribe for more! youtu.be/27AtqcYNHa8

From random gliding to ordered patterns. The movie starts with microtubules gliding on a minus-end directed molecular motor. Then, @bhagyanaths.bsky.social added a plus-end directed motor (magenta) to induce this polarity sorting and ordering process. more details here: www.pnas.org/doi/10.1073/...

Hi everyone! Fulfilling our New Year's resolution to finally move away from X, and already finding so many old friends! Stay tuned for our news, everything will be here from now on.

CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration https://www.biorxiv.org/content/10.1101/2024.12.31.630838v1

As the year ends, it’s a good time to thank @richardsever.bsky.social & the amazing @biorxivpreprint.bsky.social staff. As an affiliate I get to see a small fraction of the huge amount of work they do to transform the way science reaches us and is evaluated. Lets help them make preprinting the norm

Really bummed to have missed ASCB this year due to some last-minute circumstances, but excited that our manuscript describing an IF disassembly tool will (hopefully) be posted soon. Here's a movie of vimentin color-coded by orientation.

Advances in microscopy mean we can now do more than just observe biology—we can control it. But how far can we really push this in mammalian cells with all their (beautiful but annoying) heterogeneity? 🧪🔬(🧵)

I just made a long overdue update to microfilm guiwitz.github.io/microfilm now 0.3.0! Beyond adaptations to recent Python and Matplotlib, I added support for the great cmap library cmap-docs.readthedocs.io by @talleylambert.bsky.social for easy access to the best (and most psychedelic) colormaps!1/2

My studio at Artisans Asylum is a mess, but I’ve reached that stage where they continue to multiply… Got an old zeiss universal donated, a friend loaned me one of his many olympus CH30, + my amazing @leicamicrosystems.bsky.social DMRB, + a tiny leitz, and two (crappy) Amscopes. Love my studio time.

I desperately need to make a molten media dispenser gadget today, so come along with me on a single-day build thread, live-tweeted as progress is made. 🧵

#fluorescentfriday with a Drosophila ovariole stained for E-Cad (cyan) and F-Actin (magenta). We use the follicle epithelium as a model to study junction remodelling and barrier formation. Check out our preprint on how Rok regulates paracellular permeability: www.biorxiv.org/content/10.1...

1/5 A groundbreaking Amnesty report published today concludes Israeli authorities are committing genocide against Palestinians in Gaza. www.amnesty.org.uk/genocide-rep...

Imagine your notebook surviving for centuries to be studied by historians. This happened to transcriptions by Nicholai Miklouho-Maclay, Russian of Ukrainian Cossack descent, of a palaeontology class delivered by Ernst Haeckel (1866) This unlikely record, captures the rise of race science in Germany🧵

PLEASE TAKE OUR MONEY TO MAKE THE WORLD A BETTER PLACE. Apologies in advance for spamming but I want to make sure there is reach on here and in bluer pastures. -$10K USD max per project -international projects accepted -deadline DECEMBER 25th; weekly rolling decisions -$41K left in grant pool rn

In case you haven't seen it yet, movement is one of the most interesting and well engineered toolkits working with pose tracking data like from sleap.ai! Strong recommend 🤙

🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1

Let’s understand collective cell migration by breaking it down to its essential elements! I'm Leone Rossetti, and this is a thread showcasing what we can learn from cells journeying along narrow paths, and from the forces they generate. 1/ #EpithelialMechanics

An early Christmas present if you like Fluorescence Lifetime Imaging Microscopy, data analysis and pho-ho-ho-tons (sorry not sorry) - another postdoc position open in my group! Deadline 16th December -> www.kcl.ac.uk/jobs/100785-... Part of a super fun and collaborative Wellcome Bioimaging project 🔬

🚀 It's #FluorescenceFriday, and commissural axons are coming at you! 🧪🔬 15-hour time-lapse of chick commissural axons navigating and crossing the CNS midline (and reverse). One stack taken every 10 minutes. Pixels were color-coded in the z-axis. #LiveImaging #Neuroscience #Science #Microscopy 🧠✨