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ltdanpharm.bsky.social
Small-town Hospital Pharmacist interested in ID and Stewardship. Enjoying Colorado living. 🏔 Tennis fan 🎾.
46 posts 458 followers 378 following
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Thanks to @absteward.bsky.social for finding 2 RCTs of shorter (1 IM dose) vs. longer (3 weekly IM doses) of PCN for "Early Syphilis"! Added to the Shorter Is Better Table. 23 distinct conditions now reported in the table! References at www.bradspellberg.com/shorter-is-b...

submitted 12 days ago • 1 comment

🔥A sneak peak on the upcoming IDSA guidelines for cUTI🔥 Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections So it's still not published yet ! #idsky #medsky #utisky www.idsociety.org/practice-gui...

submitted 7 days ago • 2 comments

In patients with cUTI (including acute pyelonephritis) treated initially with parenteral therapy who are clinically improving,able to take oral medication,and for whom an effective oral option is available,we suggest transitioning to oral antibiotics rather than continuing IV Abx #idsky #EMIMCC

submitted 7 days ago • 0 comments

We are delighted to announce that we have begun to assemble a team for Bacteremia WikiGuideline. Join us to create guidelines with the humility of uncertainty.

submitted 17 days ago • 1 comment

Anyone using cefazolin/metronidazole over ceftriaxone/metronidazole for appendicitis? #IDSky

submitted 19 days ago • 2 comments

For diabetic foot osteomyelitis, Amox/clav 875/125, do you typically go with BID or TID? Assuming the patient is not obese nor underweight. #IDSky

submitted 28 days ago • 7 comments

ONE ANTIBIOTIC PK TABLE TO RULE THEM ALL Absorption takes drug into blood from GI, Vd spreads drug out to where bug calls home. And after bacteria are doomed to die, The drug’s eliminated on the porcelain throne In the Land of Notion where this table doth lie… #idSky #microsky #pharmsky #medsky

submitted 31 days ago • 12 comments

Well, it’s official folks. We’re on BlueSky full time. You want to interact with us? Do it here, don’t message on X/twitter. Don’t want to interact with us? Perfectly understandable, continue to ignore us, probably the best thing for all concerned.

submitted 36 days ago • 3 comments

Though "Oral is the New IV" with antibiotics (h/t @bradspellberg.bsky.social), it's not always easy to convince reluctant inpatient clinicians -- especially (in my experience) surgeons, who want to treat "aggressively". Interesting dynamic ... blogs.jwatch.org/hiv-id-obser...

submitted 54 days ago • 12 comments

🆕🔥Just published 🔥🆕 Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis(TB) An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline #idsky #TBsky www.atsjournals.org/doi/full/10....

submitted 55 days ago • 1 comment

Remdesivir Are most people doing 3 days for a non-covid admit diagnosis? If so (or if 5), are you continuing beyond discharge? For covid admits, are you continuing beyond discharge in any patient populations? Anyone using any specific restrictions beyond guideline (IDSA) recommendations? #IDSky

submitted 57 days ago • 2 comments

I have many thoughts! Let’s talk about Cefalexin use in bacteraemia! A new year’s thread…

submitted 58 days ago • 5 comments

What dosing does everyone use for Gram-negative bacteremia for cephalexin? 1g TID vs. 1g QID vs. Something else? #IDSky

submitted 58 days ago • 5 comments

🆕🔥Clinical Insights #JAMAInternalMed When Can a MRSA Nares Swab Guide Antibiotic Stewardship? What the Nose Knows #idsky #medsky #AMSsky #EMIMCC jamanetwork.com/journals/jam...

submitted 79 days ago • 3 comments

🔥The ADAPT-Sepsis RCT🔥 Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care. No difference was found in total Abx duration between standard care & daily CRP-guided protocol CRP failure #idsky #EMIMCC jamanetwork.com/journals/jam...

submitted 79 days ago • 7 comments

www.clinicalmicrobiologyandinfection.com/article/S119... Finally reviewed this one. @bradspellberg.bsky.social After reading this, do you trend or use CRP in any infection? Osteo?

submitted 82 days ago • 1 comment

Enterobacter cloacae complex. Ertapenem is suppressed from the culture. My lab tells me this is due to an FDA indication for use. Can anyone elaborate on this? #IDSky

submitted 86 days ago • 1 comment

I love it🔥 ASymptomatic Bacteriuria #idsky #medsky #utisky #AMSsky

submitted 87 days ago • 2 comments

For my inaugural post, Im proud to announce the publication of our Safer@Home care model. This is going to change how medicine is practiced. No need to admit pts "for IV antibiotics" anymore. Or just for IV diuresis in CHF. Or just for EtOH withdrawal. Etc. jamanetwork.com/journals/jam...

submitted 88 days ago • 16 comments

🔥Everyone's favorite #shorterisbetter table is updated🔥 "BALANCE is now published, so the table is now updated! GNB bacteremia is now listed as Bacteremia(non S.aureus) Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia " Dr.Spellberg #idsky

submitted 98 days ago • 0 comments

Non-stop infectious disease learning process, wanna be up-to-date in infectious diseases?! follow my account and always check my pinned post! Shameless self-promotion #idsky

submitted 98 days ago • 1 comment

Great to see BALANCE trial published! Large RCT of >3,000 patients, >50% in ICU, 7 days non-inferior to 14 days for (mostly) GNR BSI. Solid-organ/stem-cell transplant & neutropenia were excluded. Note: 24% in 7d group received longer duration #IDSky #TxIDSky www.nejm.org/doi/full/10....

submitted 98 days ago • 3 comments

🔥SNAP passed 3500🔥 Writing papers: Cefazolin (MSSA) and penicillin (PSSA) vs (flu)clox Recruiting: Adj clinda vs not (all) Adj cefazolin vs not (MRSA) Oral switch vs IV (all) Cefazolin +/- Erta/Placebo (MSSA) Dapto vs Vanco (MRSA) Coming "soon": Rifampin vs. none for PVIE (all) Ref: Dr.Lee #idsky

submitted 101 days ago • 2 comments

Based on several RCTs, we can provide a clear recommendation on the duration of therapy for the following antimicrobial classes (regardless of biological sex) for the treatment of acute pyelonephritis: • Fluoroquinolones: 5 -7 d • Dose-optimized β lactams: 7 d #idsky

submitted 102 days ago • 0 comments