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lucapinello.bsky.social
Computational methods for epigenetic, CRISPR genome editing and single-cell genomics. Associate Professor at MGH / Harvard Medical School. http://pinellolab.org
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Excited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...

submitted 42 days ago • 6 comments

Out today in @naturegenet.bsky.social -- PERFF-seq! With @tsionabay.bsky.social , @ronanchaligne.bsky.social, Bob Stickels, Meril Takizawa, + Ansu Satpathy, we describe this new assay to study rare populations with programmable nucleic acid cytometry. 1/n www.nature.com/articles/s41...

submitted 50 days ago • 4 comments

1/ 🎄 What’s the best gift under the tree for a computational biologist? 🎁 A new experimental assay that refines our view of gene regulation: ACCESS-ATAC! This creative idea from Richard Sherwood was developed collaboratively between his lab and mine. #Genomics www.biorxiv.org/content/10.1...

submitted 66 days ago • 2 comments

Excited to be visiting Duke University to share insights on computational methods for single-cell genomics and CRISPR genome editing! Thank you for hosting me @yi-zhang-compbio.bsky.social 🙏

submitted 71 days ago • 1 comment

Amazing new assay that allows testing of multiple DNA sequences, similar to MPRA, but in an endogenous setting. Incredible potential! Congrats @jk-swietek.bsky.social , @bartdeplancke.bsky.social and the entire team – grateful and lucky to be an early adopter. Check it out!

submitted 72 days ago • 0 comments

Attending #NeurIPS2024 this week and excited to connect with anyone exploring the intersection of #GenerativeAI, #DeepLearning, and #Genomics! I’m presenting our DNA-diffusion work at the LatinX in AI workshop today at 2:30—drop by if you’re around. Looking forward to meeting and learning from you!

submitted 79 days ago • 0 comments

Excited to visit the @humantechnopole.bsky.social 🇮🇹today to share our work on computational approaches in functional genomics! Looking forward to discussions with amazing scientists about #singlecell, #CRISPR, and #syntheticbiology. 🧬Special thanks to @nicolesoranzo for the invitation 🙏

submitted 87 days ago • 0 comments

Hello World! Very glad to be here and see the scientific community growing 🌱. It’s so refreshing to scroll through a feed full of exciting science! Looking forward to reconnecting with old friends and collaborators and meeting new ones. Let’s keep the science flowing! 🌟

submitted 98 days ago • 1 comment

Interested in #singlecell and #spatial #metabolomics? Then book your calendar for December 10th! – Our online, free event will summarize major achievements of the field in 2024. #metabolism #omics #MALDI #EPFL With Giovanni D'Angelo and our #PhD students we prepared for you a fantastic lineup. 🧵 1/5

submitted 100 days ago • 2 comments

There are ~40k postdocs in the US, according to the NIH. While PhD students generally have good support (their committees, external advisors, and classmates), the postdocs do not. To help with this, we're starting the 'Postdoc Night Science' club in Boston this Thursday! (1/3)

submitted 100 days ago • 2 comments