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lucasvandijk.nl
Bioinformatics scientist at the Broad Institute 🖥️🧬. I am working on (pangenome) graph alignment and machine learning algorithms for identifying multi-omic QTLs in the All of Us Biobank.
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Posts 17 Comments 33

The efficiency of the market

submitted 9 days ago • 1 comment

What the actual fuck is this

submitted 9 days ago • 0 comments

And now officially out in Oxford Bioinformatics :) academic.oup.com/bioinformati...

submitted 16 days ago • 1 comment

For those using WDL for their bioinformatic workflows: I wrote an extension for the @zed.dev code editor enabling syntax highlighting and integration with wdl-lsp. It also supports bash highlighting in command blocks. Installable through the Zed extensions pane! github.com/broadinstitu...

submitted 17 days ago • 1 comment

A printed thesis! Did not expect it would feel so good to have the final version physically in your hands 🙌

submitted 30 days ago • 1 comment

Diversity and consequences of structural variation in the human genome go.nature.com/4awEtaY #Review by Ryan L. Collins & Michael E. Talkowski @broadinstitute.org @harvard.edu @harvardmed.bsky.social

submitted 30 days ago • 2 comments

COMPUTER SCIENTISTS: "k" means one thousand and twenty-four STORAGE MANUFACTURERS: "k" means one thousand DISPLAY MANUFACTURERS [thinking hard]: "K" means nine hundred and sixty

submitted 40 days ago • 67 comments

Still in beta, so possible minor API changes ... but our Suffix Array library (in Rust) is ready for business. Builds on lovely ideas in CaPS-SA from @robp.bsky.social. Low mem construction. Spaced seeds. Optional crazy-low-mem search. More info on the horizon.

submitted 50 days ago • 0 comments

Anyone insight how I can configure pylsp such that it finds and autocompletes packages installed with uv?

submitted 93 days ago • 0 comments

Found ChatGPT in Fallout New Vegas: "Are you some kind of AI?" "Regrettably not, sir. All modules in this habitat are synthetic personalities atop a mundane operating system. There is no intelligence here, sir." www.youtube.com/watch?v=4XJw...

submitted 99 days ago • 1 comment

💡 Tip: You can set your website as your username on Bluesky! This is one form of self-verification, and we especially encourage official organizations and brands to do this! Examples include @npr.org @react.dev @duolingobrasil.com.br. Here's our guide for how to do this:

submitted 103 days ago • 1520 comments

I want to hear some bioinformatics war stories! What was the most weird bug or sequencing artifact you had to debug? I'll start: Did you know that changing the number of threads used by bwa-mem can influence your BAM output?

submitted 104 days ago • 1 comment

[looking at Bluesky over the past 2 days] So this is what the Cambrian explosion must have felt like

submitted 107 days ago • 27 comments

I think Philip Eng deserves a statue in the Boston common

submitted 106 days ago • 0 comments

Working through Prince's excellent "Understanding Deep Learning" book. Full of great insights like these: by optimizing using SGD we implicitly regularize the weights towards values where the gradients are similar across batches 🤯

submitted 123 days ago • 0 comments

The protein emoji was rejected in 2022. With the #alphafold #proteindesign #chemnobel, it's the perfect time for a revival ! go go @lindorfflarsen.bsky.social and col. !!!!!

submitted 139 days ago • 2 comments

submitted 253 days ago • 16 comments