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lukasvalihrach.bsky.social
Single-Cell & Spatial Transcriptomics | Group Leader at GliaOmics Lab | Head of GeneCore Facility | Co-founder at Carta Genum | Glial Cells in Health & Disease
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Beyond cell atlases: spatial biology reveals mechanisms behind disease🫶 www.nature.com/articles/s41...

submitted 5 hours ago • 0 comments

CellFM: a large-scale foundation model pre-trained on transcriptomics of 100 million human cells🤯 www.nature.com/articles/s41...

submitted 1 day ago • 0 comments

A dynamic and multimodal framework to define microglial states🔥 www.nature.com/articles/s41...

submitted 1 day ago • 0 comments

Cautions on utilizing plasma GFAP level as a biomarker for reactive astrocytes in neurodegenerative diseases molecularneurodegeneration.biomedcentral.com/articles/10....

submitted 3 days ago • 0 comments

A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity🔥 www.biorxiv.org/content/10.1...

submitted 5 days ago • 0 comments

Microglia transcriptional states and their functional significance: Context drives diversity🫶 www.cell.com/immunity/ful...

submitted 6 days ago • 0 comments

Spatial transcriptomics reveals human cortical layer and area specification🧠 www.nature.com/articles/s41...

submitted 6 days ago • 0 comments

Cell-type deconvolution methods for spatial transcriptomics🔥 www.nature.com/articles/s41...

submitted 7 days ago • 0 comments

Application of spatial transcriptomics across organoids: a high-resolution spatial whole-transcriptome benchmarking dataset www.biorxiv.org/content/10.1...

submitted 10 days ago • 1 comment

EnrichSci: Transcript‑guided Targeted Cell Enrichment for Scalable Single‑Cell RNA Sequencing www.biorxiv.org/content/10.1...

submitted 12 days ago • 0 comments

snCED-seq: high-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues www.nature.com/articles/s41...

submitted 12 days ago • 0 comments

Next generation statistical framework for next generation spatial transcriptomics data www.biorxiv.org/content/10.1...

submitted 12 days ago • 0 comments

A computational framework for mapping isoform landscape and regulatory mechanisms from spatial transcriptomics data 🤔 www.biorxiv.org/content/10.1...

submitted 12 days ago • 0 comments

ShinyCell2: An extended library for simple and sharable visualisation of spatial, peak-based and multi-omic single-cell data www.biorxiv.org/content/10.1...

submitted 13 days ago • 0 comments

Heterogeneity in pericyte inflammatory responses across age and species highlight the importance of human cell models molecularbrain.biomedcentral.com/articles/10....

submitted 17 days ago • 0 comments

Redefining CNS immune privilege🫶 www.nature.com/articles/s41...

submitted 18 days ago • 0 comments

How the Human Cell Atlas is fast-tracking new medicines😍 www.npr.org/2025/04/18/g...

submitted 22 days ago • 0 comments

SpatialAgent: An autonomous AI agent for spatial biology🤯 www.biorxiv.org/content/10.1...

submitted 22 days ago • 0 comments

Chimeric brain models: Unlocking insights into human neural development, aging, diseases, and cell therapies www.cell.com/neuron/abstr...

submitted 22 days ago • 0 comments

Putting cancer immunotherapy into spatial context in the clinic www.nature.com/articles/s41...

submitted 22 days ago • 0 comments

From Transcripts to Cells: Dissecting Sensitivity, Signal Contamination, and Specificity in Xenium Spatial Transcriptomics www.biorxiv.org/content/10.1...

submitted 23 days ago • 0 comments

Spatiotemporal Analysis of Remyelination Reveals a Concerted Interferon-Responsive Glial State That Coordinates Immune Infiltration www.biorxiv.org/content/10.1...

submitted 25 days ago • 1 comment