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margaretalexander.bsky.social
Assistant Professor UW-Madison, Medical Microbiology and Immunology investigating the mechanisms of diet, microbiota, and immune interactions in autoimmunity alexanderlab.mmi.wisc.edu
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New York Times article now up on Federal Register stuff. www.nytimes.com/2025/02/21/s... 1/n

Happy to announce that MEDI, our method to quantify dietary intake through metagenomics is out now. 🧬 🧪🧫🦠 www.nature.com/articles/s42... #metagenomics #microbiome #microbiomesky So what is MEDI? A combination of two things:

🧵 The Fight Has Come to Them: Science, Institutions & The Indirects Cut I want to take a moment to talk about the perspective behind these slides I put together. I’ve framed them to be as nonpartisan as possible—but in a moment this polarized, there are limits here. 1/

Starting my Bluesky adventure by highlighting a new paper from the lab!

I did this and you should too!

I’ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War. Same link, new title and some updates.

Happy to share our new paper in @naturemicrobiol.bsky.social on mapping spatial relationships of the human gut microbiome. We identified distinct spatial hubs between gut bacteria that reflect sub-community assemblies at the micron-scale. Led by Miles Richardson & co. www.nature.com/articles/s41...

ASM website screenshots from the wayback machine in December '24 (web.archive.org/web/20241211...) vs today. Pretty disappointing!! 🧪

Out now in @nature.com: Gut microbiome diversity across African populations - a valuable resource for further research and foundational for global health equity. 🧪 www.nature.com/articles/s41...

@lizneeley.bsky.social is publishing a weekly newsletter to track the ongoing attacks in science and higher ed. If you want to keep abreast without drowning in the news, I recommend it: buttondown.com/liminalcreat...

Let America Be America Again (Except) - Langston Hughes

This account is for sharing info with US scientists, both extramural and intramural to NIH, about attacks on science in the US. Education is power, and we can help advocate for science and medicine together. 💪🧪 We are a team of NIH people. Please ask us questions you might have.

Today we report a new compendium of human gut microbiomes with >168,000 samples By analyzing this massive dataset, we discovered distinct microbiome patterns across the globe, and show we can predict where a person lives just from their gut bacteria Now out in Cell: www.cell.com/cell/fulltex...

Microbiome science needs more microbiologists- A new commentary authored by myself and @abaumler.bsky.social www.nature.com/articles/s41...

Our study @cellpress.bsky.social finds healthy Canadians that consume a non-industrialized-type #diet can modulate their #microbiome, boost beneficial metabolites and improve their health. In just 3 weeks: LDL cholesterol ↓17% fasting glucose ↓6% CRP ↓ 14% www.cell.com/cell/fulltex...

We are hiring a new faculty member in my dept at Minn State Mankato! This person will teach human anat/phys for bio majors and run a research program with undergrad and M.S. students. I'm happy to answer questions about what it's like here as new faculty!

Always notable when the Lamming Lab drops more insight into the geroprotective effects of BCAA restriction. Never thought I’d say isoleucine is the coolest of the 3, but it is clearly super important! 😎 Awesome work!

Diet profoundly impacts the composition and function of the microbiome having consequences for health and disease. Therefore, it is important to consider diet and the gut microbiome when designing and reporting prebiotic and probiotic clinical trials. See our recent perspectives on recommendations:

Congrats to Min Bae and the Balskus Lab on their new study! Min used a Metatranscriptomics-guided approach to find a microbiome enzyme involved in the metabolism of hydrocaffeic acid. Glad I could be involved in this fascinating study! Check it out here: www.cell.com/cell-host-mi...

Hi everyone, I tried assembling a Microbiome & friends starter pack. 🦠🧫🔬 Still learning to use bluesky and might have missed you, let me know if you would like to be included. go.bsky.app/Fq36egy

Another starter pack of fine fine folks - New PIs! We're all figuring it out together! Please do (self-)nominate go.bsky.app/KJXNgfZ

Excited to share the final work from my postdoc! We explored how a ketogenic diet improves MS models, identifying bioactive compounds from the host and microbiome. Looking forward to investigating more mechanistic interactions in the Alexander Lab. Huge thanks to co-authors & Peter Turnbaugh!