Profile avatar
melissajsharpe.bsky.social
Neuroscience, Prefrontal Cortex, Dopamine, Lateral Hypothalamus, Reinforcement Learning, Wine. Senior Lecturer, USyd. Was an 🇦🇺 in 🇺🇸 (She/Her).
34 posts 1,922 followers 1,206 following
Prolific Poster
Conversation Starter

Having watched this project develop over years, I am so excited to see @jackiegio.bsky.social and @katewassum.bsky.social et al.’s paper out in @nature.com 🔥 🎉 They show that chronic stress changes the amygdala-striatal circuits involved in goal-directed action to increase habits 🧠 🧪

Actual footage of me after being added to ANOTHER department committee 😭 🧠 🧪

I chatted with a program director at NIH for a half hour just now It's clear that the people who make American science happen are doing everything they can to keep making it happen in a very difficult environment They deserve our respect and gratitude

I ❤️ this 👇 Newest from the Uchida lab in @nature.com: different aspects of distributional RL in separable populations of striatal D1 and D2 neurons 🔥

Need to thank @melissajsharpe.bsky.social and @katewassum.bsky.social for letting me invade their spaces, get help from their team to learn optogenetics. This are much easier when you are surrounded by supportive women in science. And amazing to see the effect of ACC inhibition in 2 different tasks

JUST IN: A federal judge in Massachusetts has blocked the Trump administration's rate change to NIH grants. storage.courtlistener.com/recap/gov.us...

Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.

This 👇 NIH issuing a directive to slash indirects to 15% from ~50%. This would significantly reduce the investment in universities and hospitals

Just had one of my conferences get cancelled. I breathed a sigh of relief because I can’t with all this travel (even though all awesome trips!) 😮‍💨 Anyone else relate? How do we find the right balance in academia?

Was lazy about leaving Twitter, but can no longer justify it. So glad to see so many familiar faces here. I should have moved to Bluesky sooner!

Had one of the best conferences ever at #wcbr2025. Too much fun seeing everyone (last night’s dance floor was 🔥), hearing about all the awesome science, and being in one of the most beautiful places we’ve ever been. Can’t wait for Big Sky next year 😍

🚨PIs of Training Grants and Programs, ESPECIALLY training grants that support students from historically excluded groups (T32s and T34s, IMSD, MARC, PREP, MOSAIC, etc.)🚨 We need to push back on the loss of information and the disappearance of websites about these resources.

Such a fun symposium with @bensaunders.bsky.social, Larry Zweifel, and Kate Wassum. Dopamine is not just a reward prediction error. 🧠 🧪 🧬 Thanks for joining us!

Folks at #wcbr- Come check out our symposium on lateral hypothalamus and addiction tomorrow (Wed), 4:30pm in Alpine B. Organised by @marcusweera.bsky.social! I’ll be presenting on #dopamine in lateral hypothalamus and how this changes after methamphetamine self-admin! 🧠 🧪 🧬

Today’s Winter Brain Power Hour showcased that while this administration is targeting our most vulnerable and trying to erase inclusive science—we as researchers will not stand for this. Brilliant minds united to devise real strategies to fight back. #wcbr2025

Not a bad spot for a conference (winter 🧠 in Tahoe) 🧪

Undergraduate research at UCLA is amazing. Consider applying. #glia #neuroscience #brain #CNS #UCLA 🧪

The current system of peer review, am I right? 🧪

#ACNP2024 keep this PAVLOVIAN meeting in Sydney on your radar

Check out Masa’s new paper from the lab! 🔥 🧠 🧪 We argue that #dopamine encodes the teaching signal, and #serotonin encodes a multidimensional expectation for model-based learning. In a dopamine special issue from @bensaunders.bsky.social and Camilla Bellone! www.sciencedirect.com/science/arti...

Hey #ACNP2024 attendees, UAB Neurobiology is looking to recruit 4 faculty in the areas of addiction neuroscience, iPSC/organoids, and neurodevelopmental disorders. All searches are open rank. Specific ads are forthcoming, but you can also apply at this link! uab.peopleadmin.com/postings/18636

🧠🧪🔥 PAVLOVIAN 2025 in Sydney, submit your abstracts below 👇 #neuroskyence #neuroscience

🔥 🔥 Loving this behavioral neuroscience starter park 🔥 🔥 👇

😂

The energy of 2013 Twitter but everybody's back and knees hurt more.

As always, gorgeous chemogenetic circuit dissections from Takafumi Minamimoto and colleagues. Always setting the bar for this work higher and higher. It’s crazy to see how far the NHP community has come in using chemogenetics in the past 10 years. www.science.org/doi/full/10....

More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synaptic plasticity. Intermittent rate coding and cue-specific ensembles support working memory www.nature.com/articles/s41... #neuroscience

How do DA and 5HT drugs alter reinforcement learning? Join us next Wednesday for talks by @anahitm.bsky.social, Diego Pizzagalli, Michael Browning, Roshan Cools, Emma Robinson, Yael Niv, Cath Harmer, Isabel Berwian, @nathanieldaw.bsky.social and Anne Collins. Links etc: acplab.org/2024/11/15/r...

Very excited about this! It’ll be my first Pavlovian Society meeting, and I happen to know that Mel had scored an excellent spot to hold it!

Apparently I need to put some emojis on this stuff 🧠🧪👩‍🔬 🔥Join our budding program for PAVLOVIAN 2025 in SYDNEY August 7-10 🔥 #neuroscience #neuroskyence Now accepting individual abstracts for talks 👇 It’s going to be EPIC 🤩

🔥PAVLOVIAN 2025 will be in Sydney, Australia: August 7-10 🔥 To complement our already budding program, submit an abstract for an individual talk here: forms.gle/KJ2uBnMMkprf... Due Jan 31, 2024 We will have a separate call for posters and the ECR data blitz. Stay tuned.

I can't fucking stand to think about some scared trans teen just trying to figure their shit out while all this shit is going on and feeling like there's something wrong or shameful about being trans. Being trans is beautiful. Scream it from the fucking rooftops. Don't let them take that from you.

Woo hoo! 1K new followers, welcome to 💙🦋! For science-minded folks, there are some very cool tricks 🚀… If you use any of these emojis: 👩‍🔬|👩🏻‍🔬|👩🏼‍🔬|👩🏽‍🔬|👩🏾‍🔬|👩🏿‍🔬 your post will index on a Women in STEM feed If you use 🧪 a Science feed If you use 🧠 a Neuroscience feed Go get it 🚀🧪🧠👩‍🔬💙🎊