micharapelab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Excited to be at a University, where grad student recruits can hear a first-hand account of CRISPR - from discovery to early clinical trials! #MolecularTherapeutics @jenniferdoudna.bsky.social @ucberkeleyofficial.bsky.social

submitted 10 hours ago • 0 comments

It was great to see you again, @alessiociulli.bsky.social

submitted 6 days ago • 0 comments

Really inspiring visit and talk from @alessiociulli.bsky.social of the Center for Targeted Protein Degradation at the University of Dundee in our #MolecularTherapeutics series at UC Berkeley.! It is amazing what you have built in Dundee, Alessio!

submitted 6 days ago • 0 comments

Many thanks to Dan Erlanson, Chief Innovation Officer at Frontier Medicines and the mind behind the blog Practical Fragments for giving an exciting standing room-only fireside chat at Molecular Therapeutics at @ucberkeleyofficial.bsky.social today! Thank you Dan!!

submitted 20 days ago • 0 comments

Exciting work from #MolecularTherapeutics @ucberkeleyofficial.bsky.social faculty Jim Hurley! Congratulations!!!

submitted 20 days ago • 0 comments

Very excited to highlight @jcornlab's beautiful work on the E3 ligase SCF-FBXO31, which recognizes chemically damaged proteins. Mutations in FBXO31 cause disease by substrate-rewiring, really cool. Congratulations to all authors! rdcu.be/d7WGc

submitted 28 days ago • 0 comments

Many thanks to Sylvie Callegari @wehi-research.bsky.social for her beautiful spotlight describing our recent discovery of localized, and ROS-regulated, protein degradation at mitochondrial import gates! www.sciencedirect.com/science/arti...

submitted 41 days ago • 0 comments

Scientific Director, Cal-Cryo. We are looking for an outstanding microscopist to run our cryo-EM facility (two Krioses and an Arctica), increase training, engagement, and collaboration on campus, expand our user base, and join our community of cutting edge cryo-EM researchers. tinyurl.com/ykasna3p

submitted 42 days ago • 0 comments

This paper is a stark reminder for why it is so important that we innovate drug discovery against neurodegenerative diseases now. www.nature.com/articles/s41...

submitted 44 days ago • 0 comments

Thank you to Eric Gomez for introducing TCG labs Soleil to Molecular Therapeutics faculty at @ucberkeleyofficial.bsky.social today!

submitted 48 days ago • 0 comments

I am excited to report the preprint of my postdoc work in the @olzmannlab.bsky.social! We have discovered the first lipid droplet quality control pathway with broad implications for lipid physiology and diseases associated with LD accumulation and oxidative stress! #lipidtime shorturl.at/2HqFd

submitted 49 days ago • 6 comments

Excited to share our new preprint! Exceptional work by @mikelangelipid.bsky.social identifies the first #LipidDroplet lipid quality control pathway! LD-localized FSP1 safeguards neutral lipids from peroxidation and prevents #ferroptosis. 🤩https://www.biorxiv.org/content/10.1101/2025.01.06.631537v1

submitted 49 days ago • 1 comment

Congratulations to all new Hannah Grey fellows of @hhmi.bsky.social ! www.hhmi.org/news/hhmi-na...

submitted 49 days ago • 0 comments

Congratulations to #MolecularTherapeutics and MTI faculty member Jennifer Doudna on having received the National Medal of Technology and Innovation by President Biden!!! @ucberkeleyofficial.bsky.social www.whitehouse.gov/briefing-roo...

submitted 52 days ago • 0 comments

As the sun is setting one last time in 2024 behind the Golden Gate, all the best for 2025! To a year full of friendship, health, fun and great science!

submitted 57 days ago • 0 comments

Fundamental research led to the discovery of #Remicade, the first biologic drug that has saved millions of people from suffering. The Vilceks have channeled their fortunes into supporting #immigrants. Please check out various opps on the website!

submitted 57 days ago • 0 comments

Thank you to Shigeo Murata and Kazu Iwai for writing this heartfelt obituary for Keiji Tanaka, who played such important roles in the early characterization of the proteasome and building the vibrant protein degradation community in Japan. www.cell.com/cell/fulltex...

submitted 64 days ago • 0 comments

Inspiring (and often devastating) article in @nytimes.com underscoring the human toll of neurodegeneration and why we need to work together to connect basic to translational science to find effective cures. www.nytimes.com/2024/12/22/h...

submitted 66 days ago • 0 comments

Really beautiful paper by @kjarmache.bsky.social revealing read-write mechanisms of histone ubiquitylation by Polycomb complexes - through an intricate interplay of ubiquitin binding and ubiquitin transfer. Congratulations to all authors! www.nature.com/articles/s41...

submitted 66 days ago • 1 comment

Huge thank you to @a16z.bsky.social for partnering with Molecular Therapeutics and MTI at @ucberkeleyofficial.bsky.social last night for the Faculty Founders' Reception. It was really great bringing together partners in drug discovery!

submitted 68 days ago • 0 comments

Wonderful upcoming ubiquitin meeting in 2025, close to home in Franconia ;-) www.ubiquitin-wuerzburg-2025.de

submitted 72 days ago • 0 comments

Congratulations to Thomas Sommer, who has been an inspiring leader at the MDC, and good luck for your next venture, Thomas!!!

submitted 79 days ago • 0 comments

Excited to reveal specific reactive oxygen species as sentinel molecules that control localized protein degradation at #mitochondria to adjust electron transport chain abundance, with many implications for the role of ROS in development and disease. www.cell.com/molecular-ce...

submitted 83 days ago • 6 comments

Amazing new preprint from Rape lab on the structure of the SIFI stress response regulating E3 ligase: www.biorxiv.org/content/10.1...

submitted 85 days ago • 0 comments

Wow, this is huge! (In so many ways) Congrats everybody!

submitted 85 days ago • 1 comment