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milofasken.bsky.social
Senior Scientist, Department of Biology, Emory University, Atlanta, GA. Molecular Biologist. RNA Scientist. Yeast Geneticist 🧬. British🇬🇧. Runner 🏃🏻…. Opinions are my own. Interests: RNA Decay, RNA Processing, RNA & Disease.
237 posts 3,788 followers 14,213 following
Prolific Poster

Sweet! The structure of human sweetness: Cell www.cell.com/cell/fulltex...

🧐 www.nature.com/articles/d41...

A tail of two Nab2’s…. Very interesting! Congrats! #Nab2 #PolyATail #Length #BuddingYeast #Scerevisiae #RNA www.biorxiv.org/content/10.1...

Cool! #m6A #tRNA #mRNADecay #RNA tRNA modifications tune m6A-dependent mRNA decay: Cell www.cell.com/cell/fulltex...

Nice! #Splicing Chromatin-bound U2AF2 splicing factor ensures exon inclusion: Molecular Cell www.cell.com/molecular-ce...

#RNAsky

Interesting! #mRNADecay #DisorderedRegion #Yeast

Cool! #CRISPR #Cas9 Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing: Molecular Cell www.cell.com/molecular-ce...

Nice work from Sean Johnson on "The Molecular Mechanisms of RNA Processing in the TRAMP RNA Surveillance Complex presented today at #RNASociety #Emory GA RNA Salon! @rnasociety.bsky.social #RNA #TRAMP #RNAExosome #RNADecay #Mtr4 www.pnas.org/doi/10.1073/...

Just heard a great seminar from Guillaume Chanfreau discussing this work! @guillaumechanfreau.bsky.social #TranscriptionTermination #Splicing #Efficiency #RNA #3'endProcessing #Scerevisiae #BuddingYeast www.biorxiv.org/content/10.1...

Nice! #TENT5A #SARSCoV2 #Polyadenylation #RNA

Interesting! #RNAExosome #EXOSC2 #RNADecay #RNAprocessing #Aging #Cancer www.biorxiv.org/content/10.1...

Congrats! #Integrator #dsRNA #RNAsky #RNA www.sciencedirect.com/science/arti...

Cool! #RNA

“…scientists need to communicate better — with more relevance, emotional resonance and empathy — if they are going to compete with other sources that are increasingly influential.”

Just stumbled onto this paper that found empirical evidence in support of our model that lncRNAs evolve from junk RNAs by a Constructive Neutral Evolution-like process. #RNASky #RNAbiology #RNA www.biorxiv.org/content/10.1...

#snoRNA ❄️ 🐦 www.biorxiv.org/content/10.1...

Congrats! #snoRNA #pombe www.nature.com/articles/s41...

www.biorxiv.org/content/10.1...

Biologist whose innovation saved the life of British teenager wins $3m Breakthrough prize www.theguardian.com/science/2025...

Nice! A nuclear #RNA #degradation #code is recognized by #PAXT for eukaryotic #transcriptome #surveillance: Molecular Cell www.cell.com/molecular-ce...

Interesting! UbiREAD deciphers #proteasomal #degradation code of homotypic and branched K48 and K63 #ubiquitin chains: Molecular Cell www.cell.com/molecular-ce...

Great talk at #Emory #DSAC #symposium from Jordan Goldy, grad student in Moberg and Corbett Labs, on role of #RBP #Nab2 in #insulin signaling in #Drosophila! #RNA #ZC3H14

#snoRNA www.nature.com/articles/s41...

www.nytimes.com/2025/03/10/h...

#mRNA #Export #Sub2 #DDX39B #TREX-2 www.cell.com/structure/ab...

#Turnover atlas of #proteome and #phosphoproteome across #mouse #tissues and #brain regions: Cell www.cell.com/cell/fulltex...

#RNAsky #RNAbiology

UK cover reveal for CRICK. There may be some tweaks, and a more focused quote, but this is what we have. Only say nice things. Out in November (!), pre-order from your local bookshop or somewhere nice.

Great work! #RNAExosome #Assembly #RNADecay #RNA #Mammalian Hierarchical assembly and functional resilience of the mammalian RNA exosome Tsimafei Navalayeu...Stefan L. Ameres www.biorxiv.org/content/10.1...

Interesting! #Huntingtons #Disease www.nature.com/articles/d41...

#2µ #Plasmid #BuddingYeast #Scerevisiae #Chromosome #Nucleosome www.embopress.org/doi/full/10....

Cool! #MTR4 #RNADecay #RNA #RNAExosome The #nuclear #exosome co-factor #MTR4 shapes the #transcriptome for #meiotic initiation Li Zhang, Jianshu Wang, Zhidong Tang, Zhen Lin, Ruibao Su, Naijing Hu, Yao Tang, Gaoxiang Ge, Jing Fan, Ming-Han Tong, Yuanchao Xue, Yu Zhou & Hong Cheng rdcu.be/ed5WM

Nice! Congrats, Dziembowski lab! Direct #profiling of #non-#adenosines in #poly(A) #tails of endogenous and therapeutic #mRNAs with Ninetails Natalia Gumińska...Andrzej Dziembowski rdcu.be/ed41t

#METTL3 #m6A #p300 #Acetylase

#ADAR1 #RNA #Editing

From the Besse's lab. #RNAbiology #RNAlocalization #spatialbiology www.nature.com/articles/s41...

G•A Salon #Emory & #RNASociety @rnasociety.bsky.social Anushka Nayak, Undergrad in the Khoshnevis lab, presents on #Regulation of #Candida #albicans #Pathogenicity by #RNA #Methylation 😊

G•A RNA Salon #Emory & #RNASociety @rnasociety.bsky.social @jrrnascientists.bsky.social Jordan Goldy, Grad Student in Corbett and Moberg labs, presents on role of #RBP #Nab2 in #insulin #signaling in #Drosophila 😊

Interesting! #RNADecay #RNAExosome #RNA #ncRNA Defining the roles of the #Integrator, #NEXT, and #nuclear #exosome complexes in #Drosophila #oogenesis Yongjin Lee, Adriano Biasini, Cindy Tipping, Seong Hyeon Hong, Phillip Zamore www.biorxiv.org/content/10.1...

Very cool! #Transcriptome #Nuclear #Compartments #Speckles #Polycomb Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag: Molecular Cell www.cell.com/molecular-ce...

Nice! #RNAExosome #Localization #BuddingYeast New Insights into #nuclear #import and #nucleolar #localization of yeast #RNA #exosome #subunits Valdir Gomes Neto...Carla C. Oliveira www.biorxiv.org/content/10.1...

Cool! New role for #Exportin1 #Crm1 #Xpo1 #Adaptor #NuclearPore #NPC #TranscriptionFactor Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex: Molecular Cell www.cell.com/molecular-ce...

#GeneExpression #Review #mRNA #RNA #RNAProcessing wires.onlinelibrary.wiley.com/doi/full/10....

#RNAsky, by all means

Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH. Such work is exemplified by Prof Anna Greka @broadinstitute.org in a new Ground Truths podcast. Open-access, w/ transcript, video, no ads erictopol.substack.com/p/anna-greka...

My op-ed about the importance of NIH funding was published in my hometown newspaper last week! @sciencehomecoming.bsky.social Check it out 👇🏻 www.knoxnews.com/story/opinio...

#spatialbiology #RNAbiology

How do we fight for equality for #WomenInSTEM? “Communally,” says #LaskerLaureate Joan Steitz. Steitz was recognized for her leadership in #RNAbiology and in scientific mentorship. #WomensHistoryMonth buff.ly/4gk77gQ 🧪

#MarchForScience #ATL #Science