msbr89.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

RNA xkcd.com/3056

submitted 22 hours ago • 146 comments

Peto's Paradox—that cancer does not increase with body size of mammals—was wrong. A new, comprehensive study of 263 species documents higher cancer prevalence with increasing body mass. Some large animals (e.g. elephants) have some built-in genetic adaptations www.pnas.org/doi/10.1073/... @pnas.org

submitted 1 day ago • 3 comments

This is how you can visualize gene expression data in #tidyheatmaps 🤩 jbengler.github.io/tidyheatmaps/ #rstats #dataviz #phd

submitted 2 days ago • 0 comments

🦠🔬 We are very excited to organize an EMBO workshop on Immunity in Barrier Tissues with Carolyn King! @immunologyking.bsky.social 📍 Where: Basel, Switzerland 📅 When: 26th–29th August 2025 📝 Registration deadline: 30th May 2025 Check out the program and details 🔗 #EMBOBarrierTissues @embo.org

submitted 2 days ago • 1 comment

Welcome to the 📊 Data Viz feed! This feed is designed to encourage sharing work and all kinds of discussion related to the broad field of data viz. To participate, you must: - Include 📊, #dataviz, or #datavis in your post - Be added to the account list. Sign up here: forms.gle/mcVVczaQCBJL...

submitted 363 days ago • 5 comments

A new DNA sequencing approach in which every base is first converted to one of these monsters in order to increase signal to noise in nanopore sequencing. Having engineered DNA polymerases myself, I gotta admire the feat, but boy does this look unrealistic to fly

submitted 2 days ago • 2 comments

Look at this crazy thing

submitted 2 days ago • 2 comments

Keratinocyte-driven dermal collagen formation in the axolotl skin | Nature Communications www.nature.com/articles/s41...

submitted 2 days ago • 0 comments

NIH funding freeze stalls applications on $1.5 billion in medical research funds www.npr.org/sections/sho...

submitted 3 days ago • 0 comments

Check out this incredible paper led by @tniethamer.bsky.social !!! There is a TON of wild stuff going on here that I really think is going to seed many future studies.

submitted 2 days ago • 0 comments

It's been a whirlwind of a month for me, but I want to take a moment to say I am so excited for this paper to be out! If you are interested in how the lung responds to injury and how it regenerates (or doesn't...) please go take a look! tinyurl.com/4r4zttkv

submitted 2 days ago • 1 comment

ft. @tniethamer.bsky.social, @JoePlaner, Michael Morley, @apoorva_babu, @zhao_gan, @MariaCBasil, Edward Cantu, David Frank, Joshua Diamond, Ana Nottingham, Shanru Li, Hannah Hallquist, Lillian Levin, Su Zhou, @vaughandy.bsky.social & @morriseylab.bsky.social www.sciencedirect.com/science/arti...

submitted 2 days ago • 0 comments

Is this real? I published it again on Brain @brain1878.bsky.social 😆 Truly appreciate the leadership of @rrust.bsky.social on this great project (>300 refs!)🫡👇 The blood–brain barrier: a help & a hindrance #Aging #Stroke #Neurodegeneration Crossing #BBB 😎 academic.oup.com/brain/advanc...

submitted 6 days ago • 1 comment

Curious about the history of the manifold/trajectory view of neural activity. My own first exposure was Gilles Laurent's chapter in "21 Problems in Systems Neuroscience", where he cites odor trajectories in locust AL (2005). This was v inspiring as a biophysics student studying dynamical systems...

submitted 5 days ago • 10 comments

@lionelhenry.bsky.social and I are so excited to finally announce Air - an extremely fast R code formatter! 🎉 With Air, you'll never need to worry about styling your #rstats code ever again. All you need to do is save, and Air takes care of the rest. www.tidyverse.org/blog/2025/02...

submitted 5 days ago • 18 comments

Disease diagnostics using machine learning of B cell and T cell receptor sequences www.science.org/doi/10.1126/... TL;DR: BCRs ARE ALL YOU NEED! (Well actually .... keep reading) 1/

submitted 6 days ago • 7 comments

Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget. https://go.nature.com/4gM6oW4

submitted 6 days ago • 6 comments

Here it is finally: Our mathematical methods book for life scientists! Aimed at advanced undergrads and beginning grad students, plus all those who want a deeper look at the math behind quantitative biology. @portugueslab.bsky.social. 1/3

submitted 6 days ago • 2 comments

To all people who value science as a source of truth, cures for diseases, and hope for our climate and future, here are 2 hard truths: 1) our current research ecosystem is already strained and very fragile; 2) If it gets broken it will take a generation or longer to repair. Here’s why: 1/n

submitted 6 days ago • 1 comment

The first version of NetworkCommons is now published in Bioinformatics. Next, we’ll focus on involving more of the network biology community. academic.oup.com/bioinformati... In parallel, we’ll continue expanding benchmarks and developing new applications. Interested in contributing? Reach out! ⬇️

submitted 6 days ago • 0 comments

We’re excited to share our new preprint on wheat spike development! We used spatial transcriptomics and scRNA-seq to take a closer look at the different cell types and expression domains during key developmental stages of the wheat spike. Check it out here: www.biorxiv.org/content/10.1...

submitted 6 days ago • 0 comments

Finally out! Epigenetic clock analysis reveals age acceleration in IPF lung. Another cool paper from the Yale-Leuven collaborative. Kudos Drs Korbanov and Mcdonough & team!!! #ScienceMatters #Fibrosis journals.physiology.org/doi/abs/10.1...

submitted 6 days ago • 0 comments

ok, this I did not expect!

submitted 7 days ago • 0 comments

Scientists are now organizing events, called Stand Up for Science, on 7 March in Washington, D.C., and state capitals. So far, they have attracted more than 100 volunteers from some 30 states who are hoping to rally support for research as a public good. scim.ag/4328LAD

submitted 7 days ago • 2 comments

This judge is amazing:

submitted 7 days ago • 0 comments

The sgdGMF #rstats package is now officially on CRAN: cran.r-project.org/package=sgdGMF Please give it a try and let us know if you have any feedback!

submitted 7 days ago • 1 comment

The Bacterial Virulence study section that was scheduled for today was cancelled…today! We just got the communication this morning. This is disheartening…

submitted 8 days ago • 0 comments

I had two grant proposals up for review in the NIH Bacterial Virulence (BV) study section. It was canceled without notice this morning. Without those grants, my lab must close within a year. And so the purge of scientific research in the US continues 🤬 #MicroSky 🦠🧫🧪🧬🔬

submitted 8 days ago • 57 comments

The best writing advice I've ever gotten is to remember that the first draft is where you explain it all to yourself and then the second draft is where you explain it all to your readers.

submitted 176 days ago • 55 comments

Preprint: How do axolotl regrow lost limbs that match the size of the organism? A model of coupled morphogen dynamics & tissue growth suggests that some morphogen parameters should scale with animal size, but stay constant during regeneration, i.e. show static scaling www.biorxiv.org/content/10.1...

submitted 9 days ago • 1 comment

From Canada with AI robotic self-driving laboratory👹 LUMI-Lab Autonomous development of #LipidNanoParticle for #CRISPRGeneEditing delivery LUMI-6 (brominated lipid, intratracheal)➡️ 🐭Lung editing efficiency (epithelial 20.3%) @bowang87.bsky.social cial bioRxiv 2025 www.biorxiv.org/content/10.1...

submitted 9 days ago • 0 comments

www.nature.com/articles/s41...

submitted 10 days ago • 0 comments

When you read about layoffs and terminations of HHS, NIH, CDC employees - remember: these are people, with families, plans, who worked for the health, safety, well-being of the American people. Now they are thrown by the wayside, by those who never cared about anything but themselves.

submitted 10 days ago • 0 comments

Transcriptomic re-analysis of #EndothelialCell HUVEC #Senescence Doxorubicin www.nature.com/articles/s41... Replicative www.embopress.org/doi/full/10.... Irradiation academic.oup.com/nar/article/... vs SenMayo🤔 SeneQuest #Biogerontology 2025 link.springer.com/article/10.1...

submitted 10 days ago • 0 comments

Some good news: @hannahhrncir.bsky.social ‘s primary PhD paper is finally online! This study lays the groundwork for a lot of technical and conceptual things the lab is currently working on, including light sheet microscopy for imaging entire biliary trees in mouse liver: rdcu.be/d90Br 1/4

submitted 10 days ago • 4 comments

🧬 🖥️ Need help for investigating tissue complexity from #spatial #transcriptomics data? Try out our #spacedeconv R package! 💻 Code: github.com/omnideconv/s... 📝 Preprint: www.researchsquare.com/article/rs-5...

submitted 107 days ago • 3 comments

ATTENTION (PLEASE SHARE) If anyone has or knows of any positions that might be appropriate for the NIH staff members who were terminated, please post the information in this thread. There are lots of talented and accomplished people who may be looking for new opportunities.

submitted 11 days ago • 92 comments

It's great to see the heatmap icon I contributed to bioicons.com has been used in papers. Bioicons is a open-source repository for vector graphs. There are many very nice icons on there. Please do check it out.

submitted 12 days ago • 1 comment

Howard University is now a R1 University drugmonkey.scientopia.org/2025/02/13/h...

submitted 13 days ago • 3 comments

Dishonest charts are coming from all directions, and they're only going to hit harder. Unless we push back. So, an interactive guide: Defense Against Dishonest Charts flowingdata.com/projects/dis...

submitted 13 days ago • 32 comments

There's a small contingent of people online who get angry when you say this but: Wikipedia is unquestionably the most successful utopian project of the internet age, and its destruction would be a crime against humanity

submitted 14 days ago • 8 comments

Big shoutout for the #cerebellum in this excellent @cp-trendscognsci.bsky.social piece by @aniladmello.bsky.social @0xwbj.bsky.social @amandalebel.bsky.social 🧠 “Ignoring the cerebellum is hindering progress in neuroscience” (and I may add, brain evolution) www.cell.com/trends/cogni...

submitted 15 days ago • 1 comment