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mycosis.bsky.social
Medical mycology and transplant ID
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🎥 Valley fever, aka coccidioidomycosis, may be on the rise. Discover how climate change is raising the risk of coccidioidomycosis and why it's crucial for clinicians, patients, and health systems to be well-informed for better patient care. ➡️ ja.ma/3XjVYGl #MedSky

If you know anything about #Texas it should be that a case of #Measles at Bucee’s is going to be bad…

Freezing out the NIH's funding means freezing out American innovation. Research into curing cancer, Alzheimer's, and Parkinson's all delayed. And ultimately it won't just cost us advancements in life-saving research, it will cost us lives.

#IDSky #InfectiousDiseases

An asymptomatic 17-year-old boy who had emigrated from El Salvador was found to have a pleural effusion on a chest radiograph. A small number of parasite eggs were seen in the pleural fluid. Full case details from @stanfordmedicine.bsky.social: nej.md/3CGzRTg #MedSky #PulmSky #IDSky

We invite you to participate in a survey about antifungal prophylaxis in patients with hematological malignancies. It will take 15-20 minutes. Your input helps shed light on current practices. Thank you! 🙏🦠💉 www.clinicalsurveys.net/uc/AFproph_H... @efisg-escmid.bsky.socialsky.social #Hematology

Rates of Resistance to Ceftazidime-Avibactam and Ceftolozane-Tazobactam Among Patients Treated for Multidrug-Resistant Pseudomonas aeruginosa Bacteremia or Pneumonia ⭐ Editor's Choice #IDSky

Also Tucson has a really nice air and space museum. If anyone visiting it’s a must see. Inside the world’s most famous aeroplane boneyard www.economist.com/united-state... from @economist.com

New guidelines for diagnosis and management of candidiasis from ECMM in cooperation with @ishamycology.bsky.social and @asm.org Led by @olivercornely.bsky.social @rosannesprute.bsky.social with contributions from >100 experts Author link: authors.elsevier.com/sd/article/S... #IDSky

#IDSky #MedMyco

Improved Survival in Vascular Pythiosis with Surgery and Azithromycin, Doxycycline, and Itraconazole Therapy: A Phase II Multicenter, Open-Label, Single-Arm Trial ✅ Just Accepted

Belatacept-related cytomegalovirus infection: Advocacy for tailored immunosuppression based on individual assessment of immune fitness - American Journal of Transplantation www.amjtransplant.org/article/S160... #TxID #IDSky #InfectiousDiseases

#TxID #MedMyco #IDSky

Coccidioides serology is not very reliable to diagnose coccidioidomycosis in hematological malignancy patients, and that's why antigen test should always be added. #IDSky #MedMyco #IDOnc #TxID

#IDSky #MedMyco Olorofim has low MICs in Coccidioides species. Hopefully we will get human clinical data confirming this.

Increased complications of coccidioidomycosis with uncontrolled DM. "For each 1 unit increase in A1C, the risk of hospitalizations increased by 59% (OR 1.59, p=0.005) and the risk of a cavitary lung lesions increased by 42% (OR 1.42, p=0.01)" #IDSky #MedMyco

Refractory and Resistant Herpes Simplex Virus Mucocutaneous Infections in Immunocompromised Patients: Literature Review and Proposed Definitions for Use in Clinical Trials HSV Resistance Working Group of the Transplant Associated Viral Infections Forum academic.oup.com/cid/advance-... #IDSky #TxID

Great work by CDC (Mycotic Diseases Branch) and @grthompsonmd.bsky.social. Healthcare data analysis evaluating fluc efficacy on pulmonary #coccidioidomycosis in immunocompetent patients. Again, fluc is not effective. #IDSky #MedMyco

Scientific advancements aside, this is economically irresponsible Every $1 spent by NIH generates $2.46 For example, in 2023, $47B in NIH spending generated ~$93B Halting NIH spending will LOSE the US a lot of money (and talent)

#TxID #IDSky

##IDSky #MedMyco

Concordance of non-invasive plasma cell-free DNA with invasive diagnostics for diagnosis of invasive fungal disease @anthonylieumd.bsky.social et al in Niaz Banaei lab Plasma cfDNA PCR has high concordance with bronchial sampling for diagnosing mould infections academic.oup.com/cid/advance-...

Very nice commentary by my colleague @dtangestani.bsky.social and Shmuel Shoham about the antifungal prophylaxis against Coccidioidomycosis in SOT. #TxID #IDSky #MedMyc

#IDSky #MedSky required reading: Multidrug-resistant Gram-negative bacterial infections Nenad Macesic, Anne-Catrin Uhlemann, Anton Peleg Review in @thelancet.bsky.social doi.org/10.1016/S014...

Chinese researchers describe novel tickborne virus The virus was identified through sequencing of serum sampes from patients in China with fever and recent tick bites. www.cidrap.umn.edu/t...

#IDSky #MedMyco

#TxID

Great paper to review and reference when encountering Mould fungemia (like Fusarium, Aspergillus, Mucor). #MedMyc #IDSky #InfectiousDiseases

A new study finds ants best humans at tests of collective intelligence. Learn more: scim.ag/4h2K0ID

A scientific statement from AHA on prevention, diagnosis and management of CIED infection doi.org/10.1161/CIR.... #IDSky

Excited to share our article on RSV vaccine responses in immunocompromised patients published today in @jama.com. Many thanks to @williamwerbel.bsky.social and other co-authors for their hard work and support. jamanetwork.com/journals/jam.... #IDsky #TxID.

Study finds link between recombinant shingles vaccine and delayed dementia onset (164 days on average). Effect appears stronger in women. 🤔 With reproducible code and data! osf.io/9frxm/files/... 🫡 #idsky

Arizona’s flu is trending up. #Flu #IDSky #EpiSky

Time to Staphylococcus aureus blood culture positivity is a useful marker for infective endocarditis This retrospective cohort study of >1700 cases of SAB suggests that if TTP > 13 hrs, the patient is unlikely to have endocarditis (NPV 96%, 95%CI 95-97) academic.oup.com/cid/advance-... #IDSky

What predicts severe PJP in IC hosts? Team from Canada found in MV analyses that chronic liver disease and patients requiring supplemental oxygen on admission were associated with the development of severe PJP #TxID #IDSky onlinelibrary.wiley.com/doi/10.1111/...

Reading the new NEJM Case and enjoyed among many other points, the discussion about LP and coagulopathy. #IDSky

IT'S OFFICIAL! From today, @plos.org and its journals are no longer posting on Twitter/X. If you want to carry on hearing about great science in our journal, follow @plosbiology.org on Bluesky here: bsky.app/profile/plos...

Factors Associated With Poor Clinical and Microbiologic Outcomes in Candida auris Bloodstream Infection: A Multicenter Retrospective Cohort Study #IDSky

#MedMyc #IDSky

On this day in 1981, a landmark paper in NEJM described four patients with evidence of immunodeficiency associated with PJP pneumonia, disseminated CMV, and Kaposi sarcoma. The disease would come to be known as HIV/AIDS. Revisit the paper: nej.md/41iekKD #MedSky #IDSky