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ngsorcerer.bsky.social
NGS sorcerer, computational biologist, cat dad, homebrewer. Obsessed with beer yeast, human microbiomes, and writing decent code for science. Happy to collaborate. 🇵🇱🇺🇸 Views my own.
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Having a great time at #HCMPH2025. Check out our poster on classifying beer yeast strains using RNA-seq (and maybe vote for us if you like our work đź‘€)

Excited to share our new work in @aga-gastro.bsky.social! We show that dietary fiber alters the window of susceptibility to C. difficile following antibiotic exposure. This really fantastic study was co-led by an amazing team @rinniehewlett.bsky.social @alhecht.bsky.social and Amanda PeBenito.

Tree swallow saying hello this morning

🔥

Chatbot reads your terminal window and turns your commands into a snakemake pipeline

Please submit to this if you can, your work matters in this very exciting field!

A new drug delivery method could improve treatments for inflammatory bowel disease (IBD) like ulcerative colitis and Crohn’s disease. cen.acs.org/pharmaceutic... #biosky🧪

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach đź’š

#MicroSky: Yeast in wine does not act alone—it is part of a dynamic microbial ecosystem! By applying ecology & evolution principles, Belda et al offer ways that can better predict, engineer, and improve fermentation for top-quality wine. doi.org/10.1111/1751...

Join us for our last Seminar of the semester at 11 AM tomorrow (Fri, May 2). Dr. Adam Arkin from @berkeleylab.lbl.gov & @ucberkeleyofficial.bsky.social will talk about his synthetic biology research focused on discovering, characterizing, and engineering microbes! Off-campus? DM us for the link.

It seems there are no free-living organisms known to rely exclusively on one other organism for their survival Until perhaps now Check out our latest publication in @natmicrobiol.nature.com to see how we designed an exclusive microbial reliance using GCE rdcu.be/ekepI 1/2

To restore the gut microbiome after antibiotics, the right diet (rich in carbohydrates, low in fat) was a better approach than fecal microbial transplants (in the experimental model) www.nature.com/articles/s41... www.nature.com/articles/d41...

Hot off the press in @nature.com the global evolution of #IBD across epidemiological stages www.nature.com/articles/s41... So nice to see the real-world data supporting theory in this @natrevgastrohep.nature.com Perspective www.nature.com/articles/s41... #gastrosky #IBDsky

The power of metagenomics!

#SynBYSS Thur 10 am USA CT 161st, May 1: Prof Cesar de la Fuente at UPenn & Dr Hajar(Nika) Estiri at JCVI @jcvi.org @upenn.edu 162nd, May 22: Dr Alessandra Ferrari at European Research Council & Dr Amelie Skopp at Full-Life @erc.europa.eu Zoom link for the audience: us02web.zoom.us/j/88380504839

Awesome tool, would love to see this extended for even more targeted analysis via APIs etc.

Cryptosporidium modifies intestinal microvilli: Cryptosporidium-mediated elongation of intestinal cell microvilli is controlled by exported virulence factor (MVP1). MVP1 mechanism mirrors bacterial virulence factor MAP, suggesting convergent evolution www.cell.com/cell-host-mi...

Fresh in @NatureBiotech! We developed a synthetic biology tool for tracking gene transfer in microbial communities and applied it to study plasmid hosts in a wastewater microbiome. Awesome collab with James Chappell & @joffsilberg.bsky.social and incredible students. www.nature.com/articles/s41...

Genuinely in tears laughing at the description of neutrophils by @kurzgesagt.org's Philipp Dettmer in his book, Immune

Pennsylvania could lose $973 million due to federal health research cuts. Visit scienceimpacts.org to learn more. scienceimpacts.org

A lot of what looks like microbial engraftment after FMT might actually be noise. Using placebo sequencing and culture-enriched metagenomics, we sort signal from noise. Our latest from the Surette lab: www.nature.com/articles/s41... @surettem.bsky.social @mcmasteruniversity.bsky.social

#weekendreading🔬📑 An expanded metabolic pathway for androgen production by commensal bacteria @natmicrobiol.nature.com #microsky www.nature.com/articles/s41...

My student Jaebeom Kim is presenting Metabuli, a taxonomic classifier that jointly utilize nucleotide and amino acid Information, along with Metabuli-App for easy access—at RECOMB-Microbiome. #RECOMB2025 📄 www.nature.com/articles/s41... 📄 www.biorxiv.org/content/10.1... 💾 github.com/steineggerla...

🔓Check out this #OpenAccess review by Lindsay Caesar & co. at @unm.edu & James Madison University, part of our Emerging Investigators collection, on natural product discovery from microbial communities in caves & underground mines #natprod #microsky Read in full here🔽

Watch out for scam emails if youre following @synbiobeta.bsky.social publicly, I got two of these today:

Gut #microbiota & #metabolome signatures in obese & normal-weight patients with colorectal tumors. The pathobiont F. magna is enriched on colorectal polyps of OB patients. #obesity, diet & gut microbiota cooperate in CRC tumorigenesis in OB patients. www.cell.com/iscience/ful... #MicroSky

Excited to share a new publication out! “Acute Stress-induced Alterations in Short-Chain Fatty Acids: Implications for the Intestinal and Blood Brain Barriers”. @jfcryan.bsky.social @apcmicrobiomeirel.bsky.social @sarah-janeleigh.bsky.social www.sciencedirect.com/science/arti...

🚨 New publication: We describe a novel, cultivated #Archaea species from the human microbiome: #Methanobrevibacter intestini sp. nov. ! www.microbiologyresearch.org/content/jour... #Microbiome #GutMicrobiota #NewSpecies #archaeasky #microbiomesky

The deadline for submissions to the special issue "Yeast in Microbiomes" has been extended to 15th July. We accept manuscripts exploring yeast diversity, interactions, and adaptations in diverse host environments. Hurry up and don't miss this opportunity!!! onlinelibrary.wiley.com/page/journal...

Come join us in Boston for this year's HCMPH Symposium on May 19th! This year's theme is "microbiome in food systems", however, any and all microbiome research is welcome! Register here - hsph.me/hcmph2025

We're improving #MVIF and would love to know - why is it important to you? Your feedback helps us make it better for everyone. forms.gle/Lbq5LcFAistJ... Please share. Thanks!

Glad to share my personalized link "Be a GEM: Biocontained, environmentally applied, genetically engineered microbes" authors.elsevier.com/a/1kxe%7E,3s... Published in Advanced Drug Delivery Reviews Thank Nathan Crook & Juliane Nguyen for the invitation! @elsevierconnect.bsky.social

The WHO priority list for bacterial pathogens is out. Based on factors like burden of infections, AMR etc. This is supposed to guide and highlight areas where research is urgently needed. www.thelancet.com/journals/lan...

🚨 New Perspectives article where, Deiner, Gibbons and colleagues describe the current strengths and limitations of microbial community-scale metabolic models in microbiome research. 🦠🧮 #MicroSky @gibbological.bsky.social www.nature.com/articles/s41...

I urge you to read this. The doubt, success, growth process hits home for countless academic trainees. I was on the mentor side of Maria's journey; She has the heart to put the journey on the table. Below are a few quotes that I believe stand out đź§µ: www.science.org/content/arti...