nickvangastel.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Next, our 2nd preprint of the week (!), this one driven by @madelouhart.bsky.social Previously: Mitochondrial inhibition impairs cell proliferation by constraining aspartate (ASP) availability. Here: we investigate the kinetics of ASP depletion/ proliferation impairments and...surprises ensue!

submitted 4 days ago • 3 comments

One week left for abstract submission!

submitted 6 days ago • 0 comments

Have a research story you can't wait until #ISEH2025 🏯 in September to present? Submit an abstract to the ISEH Mini Symposium before next week's deadline! ➡️www.iseh.org/2025MiniSymposium

submitted 6 days ago • 0 comments

There’s still time to submit an abstract! Join us for what promises to be a great online symposium for all interested in hematology research! And you might win a travel grant for the 2025 Annual ISEH meeting in Japan… what more do you need 🤷‍♂️

submitted 12 days ago • 0 comments

@isehsociety.bsky.social members: Vote for the next generation of society leadership here www.iseh.org/page/2025Ele... Absolutely outstanding slate of nominees

submitted 7 days ago • 0 comments

💫NEW: @valentatormenta.bsky.social, Perry & co track the endogenous redox ratio (NAD(P)H/FAD) with live imaging in the mouse skin and find that maintaining a robust redox ratio is key to clonal prevalence. www.nature.com/articles/s41...

submitted 8 days ago • 0 comments

RESEARCH | S Loopmans, @geertlab.bsky.social et al. (KU Leuven): The pentose phosphate pathway in #chondrocytes provides reducing power to ensure proteostasis necessary for #bone lengthening 🦴 🐁 https://bit.ly/3X1RuDS

submitted 8 days ago • 0 comments

@isehsociety.bsky.social community: if you’re interested in HSC research in humans then this is a must read from leaders in the field. www.exphem.org/article/S030...

submitted 19 days ago • 0 comments

If you are approaching human hematopoiesis, this is a great resource for preparing your experimental protocols! Congrats to the authors! @isehsociety.bsky.social #hemesky 🔬🩸 www.exphem.org/article/S030...

submitted 25 days ago • 0 comments

The Call for Abstracts for #ISEH2025🏯 is now open. Submit your abstract for opportunities to present your work to some of the most brilliant hematology researchers from around the globe. Deadline to submit is 12 May. https://buff.ly/4hTnEd1

submitted 14 days ago • 0 comments

There’s still time to submit an abstract! Join us for what promises to be a great online symposium for all interested in hematology research! And you might win a travel grant for the 2025 Annual ISEH meeting in Japan… what more do you need 🤷‍♂️

submitted 12 days ago • 0 comments

Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production https://www.biorxiv.org/content/10.1101/2025.02.07.637120v1

submitted 16 days ago • 1 comment

"It is impossible to be a top-line manager and administrator and mentor and researcher and writer and outreach officer and IT expert and online instructor and pedagogical innovator and recruiter and teacher and marker and external examiner and press pundit and grant bidder and editor."

submitted 174 days ago • 11 comments

Mark your agendas for the 2nd ISEH mini-symposium organized by the Junior Faculty Committee! Submit an abstract by February 26th for a chance to speak at this event. The top abstract selected from the speakers will get a travel grant for the Annual Meeting in Kumamoto, Japan in Sept 2025!!!

submitted 21 days ago • 0 comments

Take advantage of the opportunity to speak at the Mini Symposium by submitting an abstract by 26 February. Learn how and register today ➡️ https://buff.ly/3WLixTV

submitted 21 days ago • 1 comment

#NewPI and senior #postdocs in hematology, submit your abstract by Feb 26th for the opportunity to speak at our virtual mini symposium on March 26th! It’s a great opportunity to raise awareness of your research/lab and might win you a travel grant to the @isehsociety.bsky.social annual meeting!

submitted 20 days ago • 0 comments

New pre-print from Thomas Höfer, Daniel Hübschmann, @haas_lab and myself, with first authors @Esther_RCorrea @FloGrunschlager and Tamar Nizharadze doi.org/10.1101/2025... @DKFZ @NCT_HD @ChariteBerlin @hi_stem_lab BIH & MDC

submitted 20 days ago • 1 comment

Mark your agendas for the 2nd ISEH mini-symposium organized by the Junior Faculty Committee! Submit an abstract by February 26th for a chance to speak at this event. The top abstract selected from the speakers will get a travel grant for the Annual Meeting in Kumamoto, Japan in Sept 2025!!!

submitted 21 days ago • 0 comments

What a great resource! My lab has struggled in the past with some of the exact variables interrogated here. A must read for anyone diving into human HSCs! Methodological Considerations on How to Identify Human Hematopoietic Stem Cells - Experimental Hematology www.exphem.org/article/S030...

submitted 25 days ago • 0 comments

ICYMI... #ExpHem featured incredible research in 2024. Our journal has a variety of different content available, including Special Issues. Check out our collections, including guest editors @krikirschner.bsky.social @keisukeito-lab.bsky.social and more on www.exphem.org/content/spec....

submitted 26 days ago • 0 comments

We are hiring at different levels! - Lab technician for mouse experiments - Postdoctoral fellow with experience in mass spectrometry-based metabolomics For more information: www.deduveinstitute.be/jobs & www.deduveinstitute.be/research-gro... Come join our team and contribute to exciting science!

submitted 29 days ago • 0 comments

You can now submit an abstract to the second virtual Mini Symposium taking place 26 March. Submit an abstract by 26 February and register today❗Learn more: www.iseh.org/2025MiniSymposium

submitted 27 days ago • 1 comment

Watch the latest interview with ISEH President @smckinneyfreeman.bsky.social on #SimplyBlood🩸 to hear more on ISEH benefits, advice for young investigators, and the future direction of ISEH and experimental hematology. www.simplyblood.org

submitted 28 days ago • 0 comments

Really enjoyed talking about the value of joining our community of scientists, working to solve the most difficult problems in hematopoiesis, HSPCs, leukemia and more. The International Society for Experimental Hematology welcomes burgeoning scientists and group leaders. Join! #ISEH #HSC #leukemia

submitted 27 days ago • 0 comments

We are hiring at different levels! - Lab technician for mouse experiments - Postdoctoral fellow with experience in mass spectrometry-based metabolomics For more information: www.deduveinstitute.be/jobs & www.deduveinstitute.be/research-gro... Come join our team and contribute to exciting science!

submitted 29 days ago • 0 comments

In the Jan issue of @isehsociety.bsky.social journal, the very first “Society Voices article: Advice for effective leadership and hitting the ground running as a new group leader - Experimental Hematology www.exphem.org/article/S030...

submitted 33 days ago • 0 comments

5th Scientific Workshop: the Haematological Tumour Microenvironment and its Therapeutic Targeting Join us at #TheFrancisCrickInstitute, London, where leading experts from around the globe will discuss the latest research in microenvironment research. Register now! www.esh.org/conference/5...

submitted 35 days ago • 1 comment

Big congratulations to Shauni Loopmans for her excellent PhD research, now online in @natmetabolism.bsky.social. This study reveals that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival rdcu.be/d5Q65 (1/3)

submitted 43 days ago • 3 comments

Doing my first cancer research #newPI rollcall on Bluesky! Please leave a comment with what you work on so I can follow you!

submitted 47 days ago • 5 comments

The first Preprint Watch for 2025 is plentiful: 9 preprints focusing on Acute Myeloid Leukemia, but also spatial fate mapping meets barcoding, how cell fate decisions occur in hematopoietic progenitors, and more! Read now➡️ simplyblood.org

submitted 46 days ago • 0 comments

Still thinking of #endothelial cells lining #vessels as a simple uniform barrier? You’ll be surprised by how diverse they truly are! Have a look at our review to explore how these cells orchestrate #bonemarrow fate across life stages & #leukemia 👇🏻📑🤓 www.nature.com/articles/s41...

submitted 48 days ago • 0 comments

Check out our new review in @isehsociety.bsky.social journal Experimental Hematology, asking the question: to what degree is HSC dysfunction responsible for hematologic aging www.exphem.org/article/S030...

submitted 57 days ago • 0 comments

Wonderful to have this work led by @tjflemin.bsky.social along with other colleagues in our laboratory, as well as great collaborators, out on @biorxivpreprint.bsky.social! Stay tuned for exciting complementary work from @dpastoors.bsky.social, Ruud Delwel, and co coming soon!

submitted 54 days ago • 0 comments

Did you ever wonder why metastatic cancers often spread to the lungs? Amazing research from @ginevradoglioni.bsky.social! Many thanks to all collaborators, funders and patients. Wishing you all an enjoyable read and a happy new year and Ginevra a great next endeavor @salkinstitute.bsky.social

submitted 55 days ago • 5 comments

Our latest work is now available to read on bioRxiv! Very proud of this and its potential implications for patients with acute myeloid leukemia 🩸 🧪 🔬💊 eIF4A-mediated translation initiation as an AML cell vulnerability that can be co-targeted with BCL-2 inhibition www.biorxiv.org/content/10.1...

submitted 64 days ago • 3 comments

Bioart, courtesy of the NIH. All images are in the public domain and available for download as high-quality SVGs. bioart.niaid.nih.gov

submitted 70 days ago • 14 comments

Congrats to Salma Merchant for Cell Stem Cell paper: the effects of fatty acid oxidation in hematopoietic stem cells are context dependent. FAO is not necessary in young HSCs, but becomes necessary during aging, and is deleterious when upregulated by a high fat diet. www.cell.com/cell-stem-ce...

submitted 67 days ago • 0 comments

Kick off the new year with cutting-edge science. Join the NIC, Prof. Christoph Klein and @abattacks.bsky.social for their webinar on "Organoids" happening on Wednesday, 8 January 2025! www.iseh.org/ISEHWebinars

submitted 74 days ago • 0 comments

go.bsky.app/FrzB2bf Send me a message if you want to be added or you have some suggestions! The more the merrier 🩸🔬

submitted 74 days ago • 3 comments

The final #ExpHem issue of 2024 is here! Explore the latest findings, innovative studies and thought-provoking insights in the December Issue of Experimental Hematology ➡️ www.exphem.org/issue/S0301-...

submitted 75 days ago • 0 comments

For all experienced hematology researchers in Europe: we welcome you to join the EHA mentorship program (a new youngEHA initiative 🤩) As a mentor, you can really have a positive impact on the careers of young researchers! ⏱️ Deadline to sign up is 13 January 2025

submitted 76 days ago • 0 comments

✈️ Heading home from #ASH2024? Now is the perfect time to start thinking about your #ISEH2025 travel plans to Kumamoto, Japan! Plan ahead and check what the visa requirements are for traveling to Japan from your country. www.iseh.org/iseh2025

submitted 76 days ago • 0 comments

Just in time for #ASH24, our latest paper is out. We performed scRNA-seq on HSPCs over human development, maturation, and postnatal aging. We looked at dynamics of HSPC subsets, lineage biases, HSC level priming, and identified a developmentally restricted human HSC. www.nature.com/articles/s41...

submitted 82 days ago • 2 comments

Your membership makes it possible for ISEH to stay committed to fostering dialogue in experimental hematology and supporting the next generation of scientists and researchers. Renew your membership today! www.iseh.org/page/Members...

submitted 82 days ago • 0 comments

If you’re at #ASH2024, make sure to check out the talk of Nithya Balasundaram from our lab on targeting mitochondria to increase STING signaling and immune-mediated AML cell elimination! Paper 827: Monday, December 9, 2024: 3:45 PM, Seaport Ballroom ABCD!

submitted 82 days ago • 0 comments