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nicolasluxfawzi.bsky.social
My laboratory uses NMR spectroscopy to examine phase separation and interaction of proteins.
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Very excited and grateful to get this opportunity to study new aspects of TDP-43 with @nicolasluxfawzi.bsky.social @ayalalab.bsky.social and Jeetain Mittal!

submitted 6 days ago • 0 comments

#preprint Postdoc Nirbhik Acharya used NMR to find three transient helices within intrinsically-disordered regions of shuttle protein Dsk2 -- these interact with STI1. The STI1 is important for phase separation and proteasome condensates in yeast. Comments welcome! www.biorxiv.org/content/10.1...

submitted 21 days ago • 1 comment

In lab’s #FIRSTPREPRINT, we present methods to measure nanometer-scale organization around & between specific proteins in condensates in live cells. We uncover unexpected heterogeneity for a liquid-like phase with local meshwork spanning 10-50nm, stemming from ribosome biogenesis in the nucleolus.

submitted 38 days ago • 2 comments

www.biorxiv.org/content/10.1...

submitted 39 days ago • 0 comments

Proud to share: "Ensemble docking for intrinsically disordered proteins" from Dartmouth undergrad Anjali Dhar 24' and grad student Tommy Sisk. We present ensemble docking strategies for IDPs that, remarkably, seem to work! www.biorxiv.org/content/10.1... Code: github.com/paulrobustel...

submitted 66 days ago • 2 comments

Endosome maturation is orchestrated by inside-out proton signaling through a Na+/H+ exchanger and pH-dependent Rab GTPase cycling https://www.biorxiv.org/content/10.1101/2024.12.09.627558v1

submitted 116 days ago • 0 comments

Introducing our last #BlackInMicro Rising Star of 2024: Savannah Lewis! Savannah is a PhD Candidate at Stanford University’s School of Medicine, where she focuses on how natural killer cells adapt due to endemic malaria exposure, demonstrating their protective role against 1/4

submitted 133 days ago • 1 comment

www.biorxiv.org/content/10.1...

submitted 121 days ago • 0 comments

Our work on how CPEB4 mis-splicing leads to its aggregation in autism spectrum disorder is now published in Nature. rdcu.be/d2qjW I would like to thank the collaborators who joined the team during the revision process as well as the funders who supported us.

submitted 124 days ago • 1 comment

The two Network for Advanced NMR 1.1 GHz NMR spectrometers are open for use! 1.1 GHz solids at NMRFAM, UW-Madison 1.1 GHz solution at CCRC NMR Facility, UGA Submit time requests at usnan.nmrhub.org/access-uhf #NMR #NMRchat

submitted 138 days ago • 0 comments

2nd biennial conference on TDP-43 function and dysfunction in disease" 9-11 September 2025 | Trieste, Italy www.icgeb.org/tdp43-confer...

submitted 139 days ago • 0 comments