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opreskolab.bsky.social
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Don't miss the next #EMGS webinar "Oxidative DNA Damage and Repair: Impacts and Methods of Detection," presented by the EMGS DNA Repair SIG. 🧬 Register Today: emgs-us.org/event/OxiDNAWEB

🏨Get the best rate to attend the #EMGS2025 Annual Meeting by booking through our room block at the Hyatt Regency Rochester! #GenomicsConference #EMGS #RochesterNY Book Now: emgs-us.org/page/2025-ho...

🐦Register by May 31st for #EMGS2025 to take advantage of our Early Bird Registration prices! Regular Member: $525 Early Career Investigator Member: $300 Student Member: $200 Emeritus: $200 Register Here: emgs-us.org/page/2025-re...

DID YOU KNOW? The Strong National Museum of Play in Rochester has the world’s largest collection of toys and games! 🪀👾 Join us in Rochester for #EMGS2025! emgs-us.org/page/2025_EMGS

Tomorrow we have another exciting thesis defense from the Freudenthal lab! This time it is our rock climbing, dessert loving, MD/PhD candidate Luis Cortez. 🥳DM for a zoom link if interested

I ❤️ this new paper on RAD52 at replication forks, just published @nature.com. Cryo-EM reveals a unique double-ring structure that blocks reversal of replication forks. www.nature.com/articles/s41...

🔊Don't miss the next #EMGS webinar: An Applied Genetic Toxicology Career in the Pharmaceutical Industry with Zhanna Sobol on April 8, 2025 at 12:00 PM EST! Register Now: emgs-us.org/event/AGTCPI...

Excited to share our new pre-print. Direct, ensemble FRET assays developed by our lab reveal that assembly of Rad51 filaments at stalled replication sites via RPA/Rad51 exchange causes complete & irreversible PCNA unloading. Big implications for interplay between human DNA damage tolerance pathways

🐦The deadline for Early Bird Registration for #EMGS2025 has been extended to May 31, 2025! Register Here: emgs-us.org/page/2025-re...

Free webinar! Join our expert panel for a thought-provoking discussion on the critical role of fundamental research in driving innovation and breakthroughs in cancer science ✨ #KeepResearchCurious 📅 25 March 16:00 CET 🌍 Zoom us02web.zoom.us/webinar/regi...

The latest newsletter from the Sikora Lab and Front Range ILC is up! Features in this 'issue': - Quick info on 'indirect' costs for advocates - Info and registration link for our Spring '25 outreach event (on 4/11 - come join us!) - Tracy's story re: full body MRI for cancer screening #lobular

📢In response to current government restrictions, the #EMGS is pleased to offer government employees an extended deadline of May 15, 2025, for both abstract submissions and Early Bird registration for #EMGS2025. Email [email protected] for a discount code and more details.

By attacking science: We are less safe because science informs national security and medical care. We are less prosperous because science drives innovation and economic benefit. We are less free because science and democracy depend on the liberty to ask questions, and seek and share knowledge.

One more bioRxiv update (v3) on MDC1 and DNA repair dysfunction in #lobular breast cancer: www.biorxiv.org/content/10.1... We worked w @foundationmedicine.bsky.social to see whether ILC mutations manifest as repair 'loss of function', and tumor genomes say... nope :). The ILC phenotype is unique!

🔊Get ready for a new #EMGS webinar: Lessons from AI: Predicting mutability in healthy human tissues on April 16, 2025 at 11:00 AM EST. Register Now: emgs-us.org/event/AILess...

🔥🔥🔥Deadline for your abstract submission today! Don't miss out on the most exciting conference on The Ageing Genome in 2025!

I have written to Sen McCormick about my concerns on the defunding of US science. I finally received a response! He is supportive of research & thinks the F&A rates should be returned to previously negotiated rates! Thanks to @audreydrotos.bsky.social & @laurenkreeger.bsky.social for talking to him!

Annika rightfully points out that though this is positive, this is going to SERIOUSLY burden an NIH staff that is actively being further depleted. Be nice to your SROs, POs, and GMSs, folks...

📢NEW YORK STUDENTS: We are offering a Free Student Day for local students at the #EMGS2025 Annual Meeting in Rochester! Come attend sessions, connect with peers, and explore career opportunities - FREE! Just use the code STUDENT25DAY when you register! emgs-us.org/page/2025-re...

EMGS celebrates Pi Day & Int’l Day of Mathematics on 3/14/25! We recognize the crucial role of math in environmental science & genomics research. Here’s to the power of numbers in advancing our field! #PiDay2025 #IDM2025

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...

Cancer knows no borders, and setbacks in one part of the world can have lasting consequences for #patients everywhere The #EACR, and all co-signing national #cancer societies & foundations, stand in solidarity and offer our full support to our friends and colleagues in the US #StandUpForScience 🧪

Great crowd in Pittsburgh Standing Up for Science. Thanks to all of the other great speakers sharing their stories!

🧬DID YOU KNOW? Rochester is a foodie haven with the famous ‘Garbage Plate’—a local culinary delight you must try! Join us there for #EMGS2025! Register Now: emgs-us.org/event/2025EMGS #GenomicsConference #RochesterScience

Safeguarding the future of biomedical science in the United States: Cell www.cell.com/cell/fulltex...

📢TAKE ACTION: Want to comment on the implementation of a 15% rate for facilities and administration costs associated with NIH grants issued to institutions of higher education? FASEB has crafted a letter that you can customize and send to your US Senators and Representatives: t.co/mk934ez2hZ

Happy #WomensHistoryMonth and #InternationalWomensDay from the #EMGS! Did you know #EMGS has a Special Interest Group for #Women in EMGS? Learn more here: emgs-us.org/page/wemgs Chaired by @i_miousse! #WomenInSTEM #WomenInScience

A great pleasure to share our newest paper out this morning @cp-molcell.bsky.social. We show that damage to nascent RNAs should not be ignored, and under certain conditions, these can turn into DNA breaks. We call this phenomena RDIBs (RNA Damage Induced Breaks). www.cell.com/molecular-ce...

Register and submit your abstract now: The ageing genome: from mechanisms to disease www.embl.org/about/info/c...

Exciting new preprint led by @glowingtelomeres.bsky.social reveals how 6-thio-dG (THIO drug) targets telomeres in cancers. This drug “traps” telomerase in a non-productive state to prevent telomere lengthening and cancer cell growth. www.biorxiv.org/content/10.1...

Local traditional media still works! We shot this interview on the grounds of the former J&L steel mill, where buildings including my lab are today. The threat to biomedical research in Pittsburgh is on par with the threat to the mills 50 years ago. www.wtae.com/article/pitt...

Happy to share our new collaboration paper in Cell Reports. We show that translation synthesis in cancer cells occurs predominantly behind the replication fork, to fill ssDNA gaps, rather than to restart stalled replication forks “on the fly”. www.sciencedirect.com/science/arti...

Become an exhibitor for #EMGS2025 and showcase your products and services to attendees from industry, academia, government, and regulatory agencies representing a variety of disciplines across the field of genetic mutagenesis! Learn More: emgs-us.org/page/2025-ex...

Happy to report the 2025/05 NIH Biochemical and Cellular Oncogenesis (BCO) study section meeting has been rescheduled for late April. Just FYI.

Preprint alert

Just a bit over a month to submit an abstract. An intimate conference to really immerse yourself in genetic toxicology, DNA repair, environmental epigenomics and more. Meet the right people to make the connections you need!

This!!!

Yinz ready to stand up for science?

Contact your Senators and Representatives to voice your concerns about the unprecedented cuts to F&A costs! The Federation of American Societies for Experimental Biology (FASEB) has developed a letter that you can customize and send to your US Senators and Representatives. t.co/mk934ez2hZ

The 2025/05 NIH Biochemical and Cellular Oncogenesis (BCO) study section meeting that was supposed to happen tomorrow has been rescheduled to a later date, to be determined. Just FYI for folks wondering. This is so disheartening.

#EMGS members are part of a community that spans academia, government, and industry, driving innovation in genomic research. Join us for the #EMGS2025 Annual Meeting, Sept. 6-10, 2025, in Rochester, NY. Register Now: emgs-us.org/event/2025EMGS

🚨PA colleagues: "Senator Fetterman wants to hear from you about how the federal funding freeze is affecting Pennsylvania." "If your project has been impacted, please fill out our constituent impact form:" forms.office.com/g/mFv2JAPxpC Get out your Other Support and share that info!

This is the first movement from Sen. Fetterman, please fill out immediately if you have been impacted. Please circulate Penn, Pitt, PSU, Temple etc @cbartman.bsky.social