paulinefranz.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

#SIRT7 is a histone deacetylase with highly specific activity on #chromatin substrates. We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇 www.nature.com/articles/s41... (1/8) #ChemBio #ChemSky

submitted 21 days ago • 1 comment

Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now www.grc.org/histone-and-...

submitted 79 days ago • 0 comments

Dear world: this is what a graphical abstract is supposed to look like.

submitted 68 days ago • 1 comment

What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the @angewandtechemie.bsky.social Frontispiece!! ▶️ tinyurl.com/mvtecrsz @beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪

submitted 68 days ago • 2 comments

Hi there: we're happy to be on BlueSky now, too! Stay tuned as we're getting set up here for the #ChemSky community - more to follow soon!

submitted 77 days ago • 13 comments

🥳 Today we celebrated the PhD defense of our very first PhD student Kevin Schiefelbein 🤩 Kevin told us about his Lasso Peptide journey over the past four years, and it was so great to see the full story coming together. Congratulations Kevin, and thank you for everything! #proudPI

submitted 83 days ago • 0 comments

submitted 85 days ago • 4 comments

We want to thank everyone for joining and to congratulate the winners! A big thank you to all sponsors supporting this meeting! We hope to see you all next time. #LS2 #ICMT #Biophysics #LifeScience #Switzerland #Conference #Science

submitted 91 days ago • 0 comments

Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI. www.biorxiv.org/content/10.1...

submitted 85 days ago • 8 comments

Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!

submitted 85 days ago • 9 comments

Look who's here @pnas.org ✔️ @science.org ✔️ @naturecellbiology.bsky.social ✔️ @natrevgenet.bsky.social ✔️ @naturebiotech.bsky.social ✔️ @naturemicrobiol.bsky.social ✔️ @naturechemistry.bsky.social ✔️ @genesdev.bsky.social ✔️ @cellchembiol.bsky.social ✔️ @genomeresearch.bsky.social ✔️ @jcellbiol.bsky.social ✔️

submitted 92 days ago • 34 comments

MIT researchers in collaboration with Novo Nordisk report in Nature an alternative to injections for the delivery of biologic drugs. This needle-free method leverages an ingestible capsule inspired by squids that releases drugs directly into the digestive tract wall. www.nature.com/articles/s41...

submitted 93 days ago • 1 comment

On November 20, the new class of peptide-cyanobenzene dye photocatalysts developed by Xingyu have been first made public in a preprint at ChemRxiv, including a great collaboration Wei Cai in the @beatfierz.bsky.social group and Dr. Anne Sophie Chauvin chemrxiv.org/engage/chemr...

submitted 95 days ago • 0 comments

Celebrating #FluorescenceFriday and hopefully brightening your timeline with these live intestinal #organoids stained with our actin probe SPY555-FastAct.

submitted 96 days ago • 0 comments

This the (short, funny, sad) video we got to see on imaging women's brains at the CZI Imaging meeting as part of Nina Miolane's talk. Worth a few minutes and worth a share. www.youtube.com/watch?v=tX5u...

submitted 98 days ago • 2 comments

🚨 Attention #teamtomo PhD students! 🚨 12-week paid internship opportunity at Genentech. Want to see how we use cryoET in pharma? And spend the summer 2025 in the Bay Area? Details and application link here: roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...

submitted 100 days ago • 2 comments

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics

submitted 99 days ago • 176 comments

📯📯 Chemical Biology starter pack 📯📯 140 PIs & groups posting primary research in chemical biology. Please reskeet (?) & reply to this post if you want to be added! go.bsky.app/KLrTWoj Let's make ChemBioSky even greater again! #realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange

submitted 100 days ago • 48 comments

⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️ 🔄Share to help people finding its topic/field - STRUCTURAL BIOLOGY Structural Biology 1: bsky.app/starter-pack... Structural Biology 2: bsky.app/starter-pack... Crystallography: bsky.app/starter-pack... Synchrotron&CryoEM: bsky.app/starter-pack...

submitted 100 days ago • 40 comments

Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn

submitted 102 days ago • 6 comments

I am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack go.bsky.app/Jq8YaQM - if you would like to be removed/added please let me know

submitted 104 days ago • 101 comments

More than 9000 studies published in open-access journals contain figures created using the commercial scientific illustration service BioRender, which should technically mean that they are available for free reuse. But that doesn’t appear to be the case. www.chemistryworld.com/news/thousan...

submitted 121 days ago • 0 comments

Here is a starter pack dedicated to fluorescent probes, sensors and fluorophores makers. I'm sure it's incomplete, please reply to this post to be added or suggest someone. go.bsky.app/MtgJE4w

submitted 104 days ago • 5 comments

Great to see so many new people from the scientific community joining here. Welcome! I would be very happy to connect with everyone on topics such as #Science, #Chemistry, #Chemsky, #ChemicalBiology, #Antibiotics, #CovalentInhibitors, #ChemicalProteomics, #ABPP and general topics of #academia.

submitted 105 days ago • 0 comments

Happy to see our latest work in ChemEurJ🎉. Here we present a new way to get a photoactivatable BODIPY for cell imaging. This probe allows super-resolutive images in the green channel. Special thanks to Valentine, Maxence, Pascal and Mayeul. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

submitted 105 days ago • 2 comments

How to practice your #storytelling in #science? Originating from a workshop by @mirkobischofberger.bsky.social, Julius, Dani, and I started to develop the learning tool and game #SciCubes. Help us bring this project to life by ordering your set of🎲 here 👉 wemakeit.com/projects/sci... THANK YOU!

submitted 330 days ago • 0 comments

Spreading chemistry 🧪 into biology 🌱 has been one of my primary motivators to start a PhD! I'm excited to share our review on how #chemicalbiology approaches have empowered the study of chromatin ubiquitylation! Here's the link to our #OpenAccess review doi.org/10.1016/j.jm...

submitted 401 days ago • 0 comments

Histone deacylases (#HDACs and #sirtuins) have specific and quite different ways of finding their targets through #chromatin 🧬. Why do we know this, and what are we doing to study it in detail? All the info in our new review with @beatfierz.bsky.social! 👇🏻 portlandpress.com/biochemsoctr...

submitted 413 days ago • 0 comments

Check out the new review from @carlosmyruela.bsky.social on the using synthetic chromatin to investigate the function of histone deacylases! doi.org/10.1042/BST2...

submitted 413 days ago • 0 comments

Impressions from the LCBM Xmas party.!Happy holidays!!! 🎄🎁🎅🏽

submitted 437 days ago • 0 comments