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paulmoodyoxford.bsky.social
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Getting Started

If you’re doing DNA barcoding in a fieldwork or resource-limited context and you want to improve phylogenetic resolution at lower cost, here’s a method that allows the sequencing of 3 unlinked regions using long amplicon PCR and @nanoporetech.com MinION for ~€5 a sample. πŸ“· Timothy Dykes

πŸŽ„ New Dorado release (v0.9.0) – and it's big! πŸš€ Dorado polish command (experimental) for improving draft assemblies – faster & more accurate than Medaka ⚑ Faster modified base calling models πŸ”§ Usability & accuracy improvements: PolyA, Barcoding, 6mA calling github.com/nanoporetech...

Our Big Fantastic Virus Database (BFVD) is now published NAR! It contains protein structure predictions of major viral clades, enhanced by petabase-scale homology search and it's explorable on the web. 🌐 bfvd.foldseek.com πŸ’Ύ bfvd.steineggerlab.workers.dev πŸ“„ academic.oup.com/nar/advance-...

Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!

Oxford Nanopore sequencing classifies tumours mid-surgery (COI - I work for Oxford Nanopore) www.nature.com/articles/s41...