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pedneurojournal.bsky.social
Pediatric Neurology is a monthly journal that provides essential information to child neurologists and others who care for children with neurological disease.
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Developmental, Endocrine, and Ophthalmologic Outcomes in Children Prenatally Diagnosed With Midline Brain Malformations (MBM) - Data from this retrospective study in current issue of @pedneurojournal - www.pedneur.com/article/S088...

Could the use of ketamine in addition to midazolam be more effective in first line treatment for pediatric status epilepticus? Read more about this randomized controlled trial here - buff.ly/EnOEUew #Epilepsy

National survey of the Neurogenetics workforce reveals insights on program development, practice styles, inpatient care, next-gen therapeutics, and how general neurology clinics can integrate these lessons for precision medicine. www.sciencedirect.com/science/arti...

Study of 116 children with demyelinating diseases (MS, MOGAD, NMOSD) found that 26% had COVID, with 10% requiring hospitalization (no ICU/intubation). Only 7% had neuroinflammatory events post-infection. Vaccination showed no link to new events. www.sciencedirect.com/science/arti...

✨ May 2025 Editors Choice ✨ Can Diffusion Magnetic Resonance Biomarkers be used to differentiate Acute Disseminated Encephalomyelitis from Pediatric-Onset Multiple Sclerosis? Read more: buff.ly/J3GDZkR #pedneuro

How does anxiety phenotype in children with chronic tic disorders impact tic severity and premonitory urge? - Learn more in this cross-sectional single site study exploring the relationships Read more in the latest issue of #pedneuro journal: buff.ly/W7MNjb5

May 2025 #pedneurojournal issue is HERE! Includes topics such as -- 💡 Differentiating Childhood ADEM vs MS using Diffusion Magnetic Resonance Markers ⚡ Seizures may worsen neonatal HIE outcomes ⚡ EEG in preterm infants for predicting outcomes ...and so much more! Read here: buff.ly/wa1Ds9b

Delighted to share that I will be joining @pedneurojournal.bsky.social Editorial Board! I am grateful to @dryasminkhakoo.bsky.social for this wonderful opportunity. ❤️ @aanmember.bsky.social @uttyler.bsky.social @utaustin.bsky.social @stanfordneuro.bsky.social

Read more about the spectrum of genetic epilepsies with onset in infancy and toddlerhood in a cohort from India. Neuroimaging, EEG and genetic data was assessed in patients with onset of epilepsy less than 3 years of age, after acquired causes were ruled out. buff.ly/LVteWA8

What are the characteristics of SEGAs in Tuberous Sclerosis - clinical profile, imaging findings and response to treatment? Read this retrospective study to find out more buff.ly/xb7SwUG

🧠 Kids with Rett syndrome show widespread brain volume reductions on MRI vs. peers with typical or delayed development. New insights: www.pedneur.com/article/S088...

New study: Sevoflurane, but not propofol, activates the integrated stress response (ISR) in models of vanishing white matter (VWM) disease—highlighting potential implications for anesthesia choice in patients with VWM. 🔗 www.sciencedirect.com/science/arti...

Bach et al surveyed child neurology residents on difficult convos in fetal-neonatal neurology (FNN): 87% had participated, 68% had led one, but only 32% had FNN-specific training. 96% want to improve. Room to grow in training. [Link] www.pedneur.com/article/S088...

Does head ultrasound (US) with microvascular imaging (MVI) have a role in addition to grayscale US in diagnosis & monitoring for neonatal strokes? This small study provides data on increased efficacy with reads when US was done with MVI, compared to that done without. Read more - buff.ly/r6qNWYg

Does acupuncture have a role in management of primary pediatric headache? This paper in April 2025 issue does a literature review on this topic. Read more findings here - buff.ly/OAm1Fai #PediatricNeurology #Headache

FIRES is a catastrophic neuroinflammatory disorder with refractory status epilepticus. The disease management continues to pose significant challenges. Bandi et al present this retrospective review of 41 pediatric patients managed at tertiary care centers in India 🔥 buff.ly/IEYPV2o

www.pedneur.com/article/S088... Dimethyl Fumarate (DMF) shows promise for pediatric-onset MS (POMS), reducing relapses & MRI activity. With mild side effects like gastrointestinal discomfort & flushing, DMF is a potential first-line or switch therapy for POMS.

🔬 Study Alert: Ketamine + Midazolam shows better results for pediatric #GCSE! 📊 Key Findings: 76% seizure cessation in Ket-Mid vs 21% in Pla-Mid at 5 mins. Improved seizure control & fewer second doses/intubations. www.pedneur.com/article/S088...

Post-concussion clinical insomnia affects 36% of kids after concussion, leading to 3x higher symptom severity, poorer cognitive function, and longer recovery (89 vs. 57 days, p=0.004). Early intervention can ease symptom burden and speed up recovery. www.pedneur.com/article/S088...

April 2025 #pedneurojournal issue is HERE! Includes topics such as -- - Social Determinants of Genetics Referrals & Completion - Provider perspectives on care delivery for FND - Acupuncture for pediatric primary headache ...and much more! Read here: buff.ly/OYS3r5G

Explore parent experiences navigating healthcare for POLR3-Related Leukodystrophy & the opportunities for improvement for these families & those with other #rarediseases Read here: buff.ly/Me9i3bH

Explore the potential of Vagal Nerve Stimulation for children with #SturgeWeberSyndrome + #epilepsy in a retrospective analysis of 5 patients. Read more: buff.ly/Ew2abSM

Tuberous Sclerosis complex is a heterogenous genetic disorder. Parental stress is a negative predictor for QOL. In the March #pedneuro issue, Do et.al explored the elements contributing to parental stress using a multi-method survey. Read here: buff.ly/PtWGntz #neurosky #pedneuro

Love this graphic from @pedneurojournal.bsky.social on the importance of recognizing and appreciating sexual and gender diversity in pediatric neurology! ❤️

Both fingolimod and ocrelizumab are FDA approved for treatment in adult multiple sclerosis. Only fingolimod is approved for treatment in POMS. This retrospective study explores the safety and efficacy of fingolimod & ocrelizumab in treatment of POMS 🔗 buff.ly/i9f90pA

🧠 Evaluation of septum pellucidum is required in standard 2nd-trimester screening US. Absence of septum pellucidum triggers further eval & referral for counseling 🧠 This review on ASP discusses literature including management 🧠 Authors provide practical recommendations buff.ly/05thADx

Does neuropsychology have a role in MDC follow-up care of neurologically complex children? Yes! Read how a neuro NICU follow up clinic leveraged the role of neuropsychologists to elevate care for these patients buff.ly/OKdTqmP

Celebrating the women who have shaped the field of #PediatricNeurology—past, present, and future. Read about one such inspiring woman, Augusta Dejerine-Klumpke, in this historical vignette: buff.ly/rnTs75M #WomensHistoryMonth #WomenInNeurology

79% of youth with chronic tic disorders had an anxiety disorder, with anxiety most common (62%). Anxiety was linked to worse tic severity (p=0.0003) & premonitory urges (p=0.03), highlighting the need for targeted care. #TicDisorders #Anxiety 🔬 www.pedneur.com/article/S088...

👶💡 EEG & aEEG may predict neurodevelopmental impairment in preterm infants with sub-optimal sensitivity (63.9%) & acceptable specificity (87.6%). More research needed! Krishnegowda et al 📊💻 #Neurodevelopment #PretermInfants #EEG www.pedneur.com/article/S088...

The impact of war on children remains devastating, with lasting physical and psychological consequences. This editorial highlights the urgent need to address these effects in today's global conflicts. Read more www.pedneur.com/article/S088...

The weekend is the perfect time for a cup of coffee & a #pedneuro case: Wernicke Encephalopathy in a toddler with developmental delay & restricted eating: buff.ly/4kbaFVQ #pediatricneurology #neurosky

The Pediatric Neurology Editorial Board wishes you a happy #RareDiseaseDay! Rare doesn’t mean invisible—we’re here to prove it. Here’s to the patients, families, doctors, and scientists advocating and advancing care for rare diseases every day. #RareButNotAlone

✨ Editor's Choice ✨ Is There a SPOT for Remote Pediatric Stroke Evaluation in the World of Telestroke Networks? A Pilot Feasibility Study of Performing thePediatric National Institutes of Health Stroke Scale Over Televideo Read More - buff.ly/3XnMrOj #PedNeuro #ChildhoodStroke #neurosky

March 2025 #pedneurojournal issue is HERE! Includes #neurosky topics -- - Remote Pediatric Stroke Evaluation - Parenting Stress in TSC - Fingolimid & Ocrelizumab in Peds MS - Recommendations for prenatally diagnosed absent septum pellucidum & SOD & more https://buff.ly/41v6yMW

💊 Folic Acid Prescribing and Reproductive Counseling Practices of Child Neurologists for Women w/Epilepsy 🔹Only 11% of #pedsneuro prescribe folic acid (FA) to WWE 🔹VPA users more likely to receive FA (31% vs. 9.6%) ✅ 1 mg FA QD likely appropriate for most WWE ✅ Need more QI https://buff.ly/42QySuu

Hopkins Syndrome: An Uncommon Cause of Weakness in PICU 👉 Rare polio like syndrome, affects children after asthma crisis 👉 Case report of a 10 yo patient admitted to PICU with status asthmaticus, followed by development of asymmetric flaccid paraparesis.. 🔎 Read more: https://buff.ly/4k1qtKC

We are now on Instagram! Find us there — www.instagram.com/pedneurojour...

Review of Sacral Agenesis or Caudal Regression Syndrome (CRS) by Sanchez-Romero et al. This work summarizes the scientific literature, including pathogenesis, epidemiology, risk factors, genetics, clinical ft, radiologic classification, diagnosis, & management Read more: https://buff.ly/40Rvlt2

What is the current scope of ped #palliativecare training for #pedneuro residents? This needs assessment defines the current landscape, & opportunities for future #meded curriculum https://buff.ly/410IMH9

White pediatric neurology patients were 2x more likely than Black patients to complete genetics clinic visits after referral. What’s driving this gap? Read the full study here: www.pedneur.com/article/S088... #HealthEquity #Pediatrics #Genetics

Sexual & gender diversity matters in pediatric neurology! 🌈 Because every child deserves care that understands who they are. www.pedneur.com/article/S088... @dryasminkhakoo.bsky.social

For preschool children, does development of post-neonatal epilepsy increase risk for neuro-behavioral problems? Find out in the latest issue of #pedneurojournal: Neonatal Seizures and Associated Neurobehavioral Profiles in Preschool Age Children. https://buff.ly/4hqBgwv #epilepsy #Neurosky

February marks Black History Month, and today celebrates National Women Physicians Day. To honor both occasions, we encourage you to revisit a 2022 #CNS discussion with #PedNeurology editor Dr. Yasmin Khakoo and Dr. Dalila Lewis. #ChildNeurology #NeuroSky https://buff.ly/4gjFqVD

Can early postnatal cranial US be used to predict injury in moderate to severe HIE? What is the correlation w/brain MRI? Does it have a role, especially in resource limited settings? Utility of Cranial Ultrasound to Investigate Brain Injury in HIE https://buff.ly/3EbFtW4 #NeonatalHIE #NICU

Short Communication: Acute Liver Injury (ALI) Following Delandistrogene Moxeparvovec (DM) Gene Therapy Requiring Intravenous Immunoglobulin (IVIG) Read more about management of this serious adverse effect (SAE) -- https://buff.ly/4h808Ji #GeneTherapy #DuchenneMuscularDystrophy #PediatricNeurology

✨ Editor's Choice ✨ Newborn Screening for Hurler Syndrome Facilitates Early Transplant and Good Outcomes Read More - https://buff.ly/40PiNnt #PediatricNeurology #NewbornScreening

2025 issue is HERE! - Newborn screening in Hurler syndrome - Epilepsy and dev delay in patients with PTEN mutations - Communication about SUDEP - Use of CTP in peds population - Neonatal sz & neurobehavioral profiles in preschool age children pedneur.com/current

Unveiling Temporal MRI Patterns & Palliative Care in ALG11-Related CDG: Insights from Fortin et al.