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practicalfmri.bsky.social
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Never a dull moment as a facility manager! 06:00-09:00 physicist (QA) 09:00-09:30 janitor (magnet room vacuum) 09:30-10:30 plumber (sump pump failure defenses) 10:30-11:00 sysadmin (DICOM listener upgrade) Even managed a chat with a grad student & post doc as they were setting up. Lunch time!

submitted 1 day ago • 0 comments

Gut-Brain Hydraulics: Brain motion and CSF circulation is driven by mechanical coupling with the abdomen pubmed.ncbi.nlm.nih.gov/39974937/ Sit-ups for brain health?

submitted 4 days ago • 0 comments

If all politics is local, a glance at the House of Representatives map suggests everything Trump & Musk might want to do at the Canadian border will be evaluated locally for its effect on a handful of GOP House seats. The biggest resistance might yet surprise us. en.wikipedia.org/wiki/2024_Un...

submitted 17 days ago • 0 comments

Here's a good one. Turns out the University of Alabama at Birmingham is not only the largest university, it's the largest employer in the entire state! And they were in the top 30 institutions nationwide for NIH funding last year. What could possibly go wrong? www.al.com/news/2025/02...

submitted 18 days ago • 0 comments

In an era of fiscal dominance, it is ironic that those states that rely most on federal funding are those which largely voted for the current cuts. Good luck with the economic fallout!

submitted 19 days ago • 0 comments

Challenges in replicating layer-specificity of working memory processes in human dlPFC https://www.biorxiv.org/content/10.1101/2025.01.31.635930v1

submitted 23 days ago • 0 comments

Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO2, and pO2 pubmed.ncbi.nlm.nih.gov/37150946/

submitted 32 days ago • 0 comments

"We show evidence of a coupling of respiratory and pupillary dynamics during rest. Coupling characteristics changed with respiratory rates and coupling strength decreased during task engagement."

submitted 47 days ago • 0 comments

A Dynamic Link between Respiration and Arousal pubmed.ncbi.nlm.nih.gov/39379154/

submitted 47 days ago • 0 comments

Cardiorespiratory Dynamics in the Brain: Review on the Significance of Cardiovascular and Respiratory Correlates in functional MRI signal pubmed.ncbi.nlm.nih.gov/39753161/

submitted 52 days ago • 0 comments

"a higher ALPS-index indicates predominant Brownian motion of water molecules in the radial direction at the lateral ventricular body level, no more and no less."

submitted 52 days ago • 0 comments

Diffusion Tensor Image Analysis ALong the Perivascular Space (DTI-ALPS): Revisiting the Meaning and Significance of the Method pubmed.ncbi.nlm.nih.gov/38569866/

submitted 52 days ago • 0 comments

Really clever reasoning in this idea. It considers the hemodynamic response across the cortex as a spatial-temporal phenomenon. (Like 4D space-time!) If you use or are interested in ME-ICA for fMRI, you should read this paper.

submitted 59 days ago • 1 comment

Differentiating BOLD and non-BOLD signals in fMRI time series using cross-cortical depth delay patterns https://www.biorxiv.org/content/10.1101/2024.12.26.628516v1

submitted 62 days ago • 0 comments

New paper in Imaging Neuroscience by Daniel E.P. Gomez, Jonathan R. Polimeni, and Laura D. Lewis: The temporal specificity of BOLD fMRI is systematically related to anatomical and vascular features of the human brain doi.org/10.1162/imag...

submitted 67 days ago • 0 comments

Bottom line: measure more things, people! Many, many more things!

submitted 71 days ago • 0 comments

Time of day has a large effect on the BOLD signal, with sleep deprivation producing several large changes. Will the scan time be held constant through the study? And what measures will be taken to evaluate recency of sleep or sleep deprivation over a week, a month? (5/5)

submitted 71 days ago • 0 comments

Caffeine has been shown to drive resting CBF and affect BOLD fMRI. How will you account for caffeine intake before each scan session? (4/5)

submitted 71 days ago • 0 comments

Arousal is a prime determinant of fMRI responses, changing within & between scans. How will you account for the likelihood of changing arousal on repeat scans? Will only experienced subjects be used, and will an assumption be made about arousal, or will arousal be assessed? (3/5)

submitted 71 days ago • 0 comments

What is the sex breakdown of the pilot group, and what is the justification for this breakdown? If female subjects are to be included, how will you account for the hormonal changes during the menstrual cycle? (2/5)

submitted 71 days ago • 0 comments

I just posed the following questions to someone starting a pilot study, attempting to determine test-retest reliability of fMRI measures ahead of a study on psychedelics. But it seems like these are questions every fMRI study should answer, no? (1/5)

submitted 71 days ago • 0 comments