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In a #Playback event Karolinska’s own Austeja Baleviciute will present a #preprint from about how tumour-associated macrophages enhance tumour innervation and spinal cord repair. 🚧🏗️🛠️ www.biorxiv.org/content/10.1...

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Tomorrow, in #PreprintClubHub1 Mount Sinai’s Meredith Ramba will present a #preprint about the way IRF7 controls spontaneous autoimmune germinal centre and plasma cell checkpoints. 7️⃣7️⃣7️⃣ www.biorxiv.org/content/10.1...

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Today CeMM’s Daniel and Sophie in #preprinthub2 will present a #preprint from @umcgroningen.bsky.social @darshakbhatt.com on how programming #alphavirus with IFN-g overrides the adverse effects of #macrophages on oncolytic virotherapy 🦠🔋💊 www.biorxiv.org/content/10.1...

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Reaching out to the #immunosky — would you want us to discuss your preprint? Tag us! We would be happy to provide feedback. 📝

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Today, in #PreprintClubHub1 Oxford’s Alfie Carter will present a #preprint about the way a bi-specific T cell-engaging antibody triggers protective immune memory and glioma microenvironment remodelling in immune competent preclinical models. ✌️🧠🐁 www.biorxiv.org/content/10.1...

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Today in #preprinthub2 Miquel and Victoria from #CeMM will present a #preprint from Teresa Manzo group on how palmitate-induced mitochondrial damage restricts histone acetylation in CD8+ T cells to impair anti-tumor immunity ⚡️🪫🤹‍♀️ www.biorxiv.org/content/10.1...

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✍️ Today #preprinthub2 ’s @cleeterichter.bsky.social will discuss a #preprint from Jeff Rathmell lab on how metabolic adaptations rewire CD4 T cells in a subset-specific way during human critical illness, with or without sepsis 🔥🙅‍♀️ 👇 www.biorxiv.org/content/10.1...

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In our Wednesday #DoubleFeatureEvent, Mount Sinai’s Frederika Rentzeperis will share a #preprint about the way vagal TRPV1+ sensory neurons regulate myeloid cell dynamics and protect against influenza virus infection. www.biorxiv.org/content/10.1...

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On Wednesday, February 12th, in #PreprintClubHub1 Karolinska’s own Austeja Baleviciute will present a #preprint from about how tumour-associated macrophages enhance tumour innervation and spinal cord repair. 🚧🏗️🛠️ www.biorxiv.org/content/10.1...

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Hope you had a wonderful weekend 🦋 Take a moment to read our feedback on this preprint👇 www.preprintclub.com/preprint-rev...

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NEW @preprintclub.bsky.social Journal Club of @biorxiv-immuno.bsky.social paper by @makris1.bsky.social @actonlab.bsky.social showing that loss of podoplanin in fibroblastic reticular cells results in decreased antibody levels and smaller germinal centres after immunization

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Today in #preprinthub2 Mariia Saliutina from Charité will present a #preprint on how #single-cell spatial immune repertoire reveals heterogeneity of lymphoid aggregates in human immune disorders 👭🧬📱 www.biorxiv.org/content/10.1...

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Registration is now open for the next ImmunoSchool! This year’s theme: "10 Years of Discovery in Immunotherapy." We’ve put together a stellar lineup of speakers—don’t miss it! Free registration @ bit.ly/3WFj0Hc #ImmunoSchool #Immunotherapy #CancerResearch

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🫡 Our feedback to this preprint is now published here: www.preprintclub.com/preprint-rev...

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Today in #preprinthub2 @reinisjiri.bsky.social & Mustapha Jaiteh from CeMM will present a #preprint on chronic viral reactivation, immune response, and clinical outcomes in acute #COVID19 and post-acute sequelae 😷💉🦠 www.biorxiv.org/content/10.1...

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In our Wednesday #DoubleFeatureEvent, Oxford University’s own Lisha Jeena will share a #preprint on the way type I #IFN, induced upon respiratory viral infection, impair lung metastatic initiation. 🫧🦠🫁 www.biorxiv.org/content/10.1...

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On Wednesday, January 29th, in #PreprintClubHub1 Mount Sinai’s Annie Khamhoung will present a #preprint about how astrocyte-derived MFG-E8 facilitates microglial synapse elimination in #Alzheimer’s disease mouse models. 🧠-🐭-💃 www.biorxiv.org/content/10.1...

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Today in #preprinthub2 Martin Murauer & Lisabeth Pimenov will present a #preprint on how #IL-10 Targets IRFs to Suppress #IFN and Inflammatory Response Genes by Epigenetic Mechanisms @weillcornell.bsky.social ✋🧬🔥 www.biorxiv.org/content/10.1...

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☃️ This year’s #preprinthub2 kicks off w/ a #preprint by @colllab.bsky.social @wwiem-qub.bsky.social “Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action”discussed w/ @codoncurator.bsky.social & Chrysanthi Kagiou ⛔️🔥💊 bit.ly/42a0dr1

submitted 43 days ago • 1 comment

👀 Read our preprint highlight w/ @natrevimmunol.bsky.social on in vivo enhancement of tumour-specific T cells via peptide–MHC-pseudotyped retroviral gene delivery 👇 www.nature.com/articles/s41...

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We wanted to remind you that you can read our preprint feedback under the “Community reviews” button on @biorxivpreprint.bsky.social 😊

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For the last preprint club of 2024 Falk Ponath of hub1 from MD Anderson will present a preprint about the prognostic potential of conserved immune patterns in sentinel lymph nodes of melanoma patients to identifying patients at risk of metastatic disease. www.biorxiv.org/content/10.1...

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And Erika McCartney from Toronto will present a preprint about the effect of Podoplanin expression on the phenotypes and immunoregulatory properties of fibroblasts in lymph nodes. www.biorxiv.org/content/10.1...

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Today #preprinthub2 Tamina and Joel will present a #preprint from @miriammerad.bsky.social @samhegde.bsky.social @sinaiimmuno.bsky.social on how myeloid progenitor dysregulation fuels immunosuppressive #macrophages in tumors ✍️💥 🥸👇 www.biorxiv.org/content/10.1...

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On Wednesday Dec. 11, Alexander Tepper from #hub1 and Mount Sinai will present a preprint from Xiaowei Zhuang’s lab about a platform for multimodal in vivo pooled genetic screens. www.biorxiv.org/content/10.1...

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And Maria Armeropineiro from Oxford will present a preprint from Kipp Weiskopf’s lab about antibody therapies that stimulate macrophage-mediated destruction of B-cell lymphoma. www.biorxiv.org/content/10.1...

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This platform keeps getting better and better! 😍🦋 The @preprintclub.bsky.social joined the bright side. #immunosky Share and follow for inter-institutional, trainee community reviews of preprint articles. #preprints #openacess www.preprintclub.com

submitted 78 days ago • 2 comments

#PreprintClub is now on Bluesky! Who are we and what are we doing? We are a group of enthusiastic scientists that gather together once a week to discuss fresh preprints in the field of #immunology. 🦠🧬

submitted 78 days ago • 1 comment