rprzanowska.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

One of the many, many “pauses” and cancellations devastating our next generation of researchers. “The NIH Intramural Program has paused the recruitment of IRTAs, CRTAs, and Visiting Fellows in all training programs pending guidance from Health and Human Services. Check back daily for updates.”

submitted 8 days ago • 9 comments

This is an exciting piece of research that brings us closer to an informed choice of therapy for individual patients. I am grateful to my PI and all collaborators for letting me learn how to start a translational project and how far it can reach. Thanks to UVA Engineering for highlighting our work!

submitted 26 days ago • 0 comments

#Rstats trick: use case_when(). I use it almost every week. No more nested if else gist.github.com/crazyhottom...

submitted 44 days ago • 3 comments

New university housing for graduate students #snowday #snowweek #work-life-integration

submitted 46 days ago • 0 comments

Happy to close 2024 with my last first-author publication from PhD thesis: "DNA replication in primary hepatocytes without the six-subunit #ORC" in @elife.bsky.social. This study challenges existing paradigms in #DNAreplication. 🧵(1/4) elifesciences.org/reviewed-pre...

submitted 55 days ago • 3 comments

Thrilled to share my first-author postdoc paper, "Patient-derived response estimates from zero-passage organoids of luminal breast cancer," just published in Breast Cancer Research! This project brings us closer to personalized treatments for #BreastCancer patients. 🧵(1/5)

submitted 55 days ago • 2 comments

Feeling so hopeful for 2025 after an amazing close to 2024! Grateful for a wonderful family vacation to recharge and thrilled to have two first-author papers published as a late birthday surprise on the very last day of the year. Wishing everyone a happy and fulfilling new year!

submitted 55 days ago • 2 comments

Bioart, courtesy of the NIH. All images are in the public domain and available for download as high-quality SVGs. bioart.niaid.nih.gov

submitted 71 days ago • 14 comments

Another beautiful example of #lncRNA #structure-function study from Dutta lab at UAB. Grateful to add a small puzzle piece to this work. Congratulations Xiaoxiao and all involved!

submitted 61 days ago • 0 comments

A 36-base hairpin within lncRNA DRAIC, which is modulated by alternative splicing, interacts with the IKKα coiled-coil domain and inhibits NF-kB and tumor cell phenotypes https://www.biorxiv.org/content/10.1101/2024.12.23.629241v1

submitted 63 days ago • 0 comments

Many academics point to bioRxiv as “the one thing improving science publishing”. If so, the one thing you all can do is persuade colleagues to submit and make this a norm. 1/2

submitted 66 days ago • 15 comments

Our recent preprint about using a custom chromatin capture assay, to identify potential target genes for cancer risk variants. For several variants, the target gene for cis regulation was ~ +/- 1Mb away, and we experimentally confirmed this for multiple targets. www.medrxiv.org/content/10.1...

submitted 81 days ago • 1 comment

We often hear that nutrition needs are dynamic over your life, that some things are more important as kids (calcium), that there are super foods. If you are like me, these concepts can seem a bit vague. This new @pnas.org paper is a great resource. 🧵 🧪 #PEDSky #MEDSky www.pnas.org/doi/full/10....

submitted 75 days ago • 3 comments

"We report that numerous “miRNAs” previously reported in EMT and cancer contexts are not incorporated into RISC and are not capable of endogenously silencing target genes, despite the fact that hundreds of publications in the cancer field describe their roles" www.biorxiv.org/content/10.1...

submitted 75 days ago • 5 comments

Following @daylab.bsky.social’s nice paper on eRNA regulating Fos, and then our paper showing eRNA mediated regulation of NR4A2, here’s yet another eRNA controlling NPAS4. LncRNAs for the win in the brain! www.science.org/doi/10.1126/...

submitted 75 days ago • 1 comment

Hello Bluesky 🤠 Our very first post is about our recent paper in Nucleic Acids Research: so-called PUN motifs are repetitive elements enabling proteins to catalyze #RNA folding and RNA-dependent #condensate formation ( #LLPS). 15% of human proteins contain 3 or more PUN motifs. See bit.ly/4fZ3f54.

submitted 76 days ago • 1 comment

Are you a senior PhD student or postdoc? Do you have a cool science story to tell? Do you want to visit Buffalo when the weather is perfect? Then apply for the Emerging Leaders Seminar Series at Roswell Park! DM or email me with questions. (RT please!) www.roswellpark.org/education/pr...

submitted 76 days ago • 0 comments

If you ever wondered why #SystemsBiology, this movie is for you! Prepared by Sarah Groves from Janes lab at UVA BME and SASCO Center. youtu.be/rmuj1cyIn44?... WHAT is systems biology? WHY do we need systems approaches in cancer? HOW do systems approaches get used in the clinic today?

submitted 77 days ago • 0 comments

Cool new work from Jenn Prescher and coworkers @ucirvine.bsky.social, “RNA lantern” technology for bioluminescence imaging of RNA transcripts www.nature.com/articles/s41...

submitted 85 days ago • 3 comments

An update on our Dept faculty search. We had 165 applications and after reviewing, we discussed the top 30. 12 were selected for Zoom interviews, and then we discussed and selected 5 for in person interviews which start soon. For those still interviewing, Zoom questions are attached. Good luck!

submitted 86 days ago • 6 comments

MirGeneDB 3.0 is published. Great teamwork and substantial improvement of database, Taxon sampling and we took over nomenclature of novel genes and families, too academic.oup.com/nar/advance-...

submitted 87 days ago • 2 comments

🧬 Excited to share our new preprint! DMS chemical mapping, a key technique for studying RNA structure. Everyone assumes low DMS reactivity = Watson-Crick , high = non-WC. However, analyzing 7,500 RNA structures containing known 3D structures reveals it's not that simple. doi.org/10.1101/2024...

submitted 92 days ago • 5 comments

Check it out! The RNA Society 2025 Meeting Site is now live! Registration will open in January RNASociety Note the fabulous artwork by former EmoryBCDB student Dr. Carly Lancaster- make your plans now to join us in San Diego May 27-June 1, 2025

submitted 99 days ago • 1 comment

sunburn is from ribosomes stalled by UV damage to RNA? super cool www.sciencedirect.com/science/arti...

submitted 91 days ago • 6 comments

Rapid folding of nascent RNA regulates eukaryotic RNA biogenesis https://www.biorxiv.org/content/10.1101/2024.11.26.625435v1

submitted 91 days ago • 0 comments

I’m thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation! www.science.org/doi/10.1126/...

submitted 95 days ago • 3 comments

How to write a grant? 1. The application is for the reviewer, not you, the applicant. 2. Communicate in stories. 3. Make your story cohesive—leave no puzzling gaps. 4. Make your story resonate to keep the reviewer reading. 5. Accept chance and noise in peer-review. www.pnas.org/doi/epub/10....

submitted 93 days ago • 3 comments

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/

submitted 92 days ago • 33 comments

Take a look at this amazing work of @camthevirusguy.bsky.social from Janes lab at UVA BME. This is what I call the scientific advance! Congratulations 🎉👏 www.science.org/doi/10.1126/...

submitted 96 days ago • 0 comments