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ryanhisner.bsky.social
Teacher. Learner. Investigating mysteries of SARS-CoV-2 evolution.
270 posts 7,180 followers 182 following
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Posts 9 Comments 41

Our analysis of the second incursion of H5N1 viruses (genotype D1.1) into dairy cattle in the US is now posted to virological virological.org/t/timing-and...

submitted 15 days ago • 1 comment

Great new study on LP.8.1(.1) by @snpoehlm.bsky.social. Provisional takeaways: • Slight increase in antibody evasion • No change in S1/S2 cleavage (despite additional R in LP.8.1.1 FCS (now RSRRRAR) • Possibly even stronger ACE2 binding than revealed by standard assays • Poor lung-cell entry 1/4

submitted 11 days ago • 3 comments

More evidence that there were no intermediates between the early A and B lineages of SARS-CoV-2. academic.oup.com/ve/advance-a... This can also be seen in an unpublished paper on Wuhan sequences from Jan 2020 (A=S, B=L...I think).

submitted 15 days ago • 5 comments

Its even shallower than that. A lot of Americans, even smart ones like Nate, worship capital and believe that wealth correlates with intelligence. To not believe this forces you to re-evaluate who is rich in our society and why. Nate cant handle that.

submitted 17 days ago • 7 comments

A few thoughts on Universal Basic Income.

submitted 17 days ago • 11 comments

There are a small number of insertion hotspots in the SARS-CoV-2 genome. One is the furin cleavage site (FCS), around S:680. And if you look at enough insertions, you notice they're nearly always dominated by G nucs—& secondarily C's. This is the latest, from an XEC in Spain. 1/3

submitted 21 days ago • 1 comment

Science is for everyone. docs.google.com/forms/d/e/1F...

submitted 23 days ago • 9 comments

Looking forward to digging into this. Co-authors include @mghafari.bsky.social & @mugkraemer.bsky.social. "Large-scale genomic surveillance reveals immunosuppression drives mutation dynamics in persistent SARS-CoV-2 infections" www.medrxiv.org/content/10.1...

submitted 23 days ago • 1 comment

Department of Graph Enormities

submitted 24 days ago • 0 comments