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schalchlab.bsky.social
Structural and molecular biologists with a fascination for chromatin and gene silencing. University of Leicester.
4 posts 416 followers 446 following
Getting Started

Please RS/RT. #GordonConference "Histone and DNA Modifications" Program is now online 🍾 #epigenetics #chromatin #histones 20.-25. July. Il Ciocco 🇮🇹 Register now: ➡️ shorturl.at/AtAjz Exciting speaker lineup, many slots for talks selected from abstracts

🧬 1/ Heterochromatin protein 1 (HP1) still surprises us after all these years: It simply sticks to chromatin when pericentric heterochromatin domains – the chromocenters – are activated in mouse fibroblasts and acts as a local rather than global repressor. New preprint: doi.org/10.1101/2024...

I am recruiting a postdoc with experience in Protein Biochemistry, Structural Biology & Chromatin Biology. If you are passionate about the complex world of chromatin modifications, please contact me for more details 🙏. Location: SAiGENCI, Adelaide, Australia 🦘🍷🏄🏖️🇦🇺

📢 #PhD Position 🎓 @leicstructbio.bsky.social @mcbleicester.bsky.social. Developing protein-based therapies for mesothelioma. Work with experts in epigenetics & cancer biology. Apply by Jan 10, 2025. #PhDSky #AcademicSky Details: www.schalchlab.org/mesoinject

We have an exciting and multidisciplinary fully-funded BBSRC MIBTP #PhD position between my lab and Massimo Cavallaro's lab coupling genomics, transcriptomics, and mathematical modelling to investigate the regulation of gene expression. Deadline: 16th January 2025. www.findaphd.com/phds/project...

🎓 Exciting #PhD opportunity in our lab at @mcbleicester.bsky.social and @leicstructbio.bsky.social. Join the BBSRC-funded MIBTP programme for a 4-year fully funded studentship with comprehensive training in year 1 + research project years 2-4. #PhDSky #AcademicSky Details: tinyurl.com/4fhavzxh

Gutting when you find your dream project done and dusted on bioRxiv. Du et al. performed an impressive tour-de-force to solve the Clr4-H3K14ub structure. Great to see that the ubiquitin-binding region we found by XDS-MS matches the crystal structure perfectly! www.biorxiv.org/content/10.1...

Putting together packs of transcription and Chromatin people - Nominate others to add! go.bsky.app/5zgpZfg

In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-electron tomography https://www.biorxiv.org/content/10.1101/2024.02.21.581285v1