seamusholden.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

First senior-author paper is out today in the Journal of Microscopy! 🧪🔬 We present the first 3D printed microscope where both the optics & frame are entirely 3D printed - a low-cost, accessible, and reproducible tool for histological imaging! onlinelibrary.wiley.com/doi/full/10.1111/jmi.13398

submitted 3 days ago • 1 comment

New paper out 🎇 It has been 13 years since @owenlabuob.bsky.social and co. published a stellar protocol on how to measure membrane order with smart probes! Since then, there has been new dyes, imaging modes and biology! We wrote a protocol for Nature Protocols: www.nature.com/articles/s41...

submitted 9 days ago • 1 comment

I have a PAID 6 weeks undergraduate summer internship in my lab. You'll use #FRET #biosensors, #confocal #microscopes, and #RaspberryPi to try to discover how low humidity affects leaf development. @sheffieldpps.bsky.social @rmsearlycareer.bsky.social Project 5: www.rms.org.uk/community/ne...

submitted 21 days ago • 1 comment

Registration is now open for The Biology and Physics of Prokaryotic Chromosomes meeting in York, UK. 16-19 September 2025

submitted 37 days ago • 0 comments

Off to Oxford for Mirjam Kummerlin's viva today, looking forward to fun discussions about some very nice single molecule imaging

submitted 37 days ago • 0 comments

I was looking forward to this one! An open source software for fast reconstruction of 3D structured illumination microscopy (SIM) from Xi Peng's lab : www.cell.com/the-innovati... Matlab-based, code here: github.com/Cao-ruijie/F...

submitted 46 days ago • 4 comments

Interested in a single molecule bacteriology PhD? Deadline 16th Jan. Location Warwick, UK Broad topic is the physical biology of the bacterial cell wall. Could suit almost any scientific background, eg biology, physics, biochemistry, chemistry, computer science. www.findaphd.com/phds/project...

submitted 52 days ago • 0 comments

Insightful thread by @erikvannimwegen.bsky.social arguing for nudges in the publishing system instead of blowing it up. What I find curious is how our truly vast publishing ecosystem is stubbornly resistant to any experimentation. eLife tries a couple things and gets vilified. What the heck! 1/2

submitted 70 days ago • 1 comment

Finally! Who's is next (Germany, looking at you 🧐). www.timeshighereducation.com/news/finland...

submitted 70 days ago • 1 comment

My main job in 2024 was assembling teams for several exciting and ambitious projects on bacterial cell wall biology. New lab members and new collaborations. Really happy to see that how collaborative and supportive everyone is. Looking forward to future discoveries!

submitted 70 days ago • 0 comments

Really proud of this one. Nothing speaks more true to my sentiments on the value of open source and accessible hardware. Hoping it can be a guide for fellow researchers. Look out for my next collab with @sarraceniamason.bsky.social, hopefully this coming year! pmc.ncbi.nlm.nih.gov/articles/PMC...

submitted 71 days ago • 8 comments

www.unige.ch/sciences/chi... Amazing news!!!!! Congratulations @gautamdey.bsky.social and @dudinlab.bsky.social

submitted 72 days ago • 1 comment

submitted 73 days ago • 0 comments

If there's any other miniature wargaming nerds on here, staff at paint manufacturer Vallejo are on strike. You can support them by boycotting the company until it is resolved www.polygon.com/news/490371/...

submitted 72 days ago • 1 comment

It was wonderful to visit COMPARE at University of Birmingham today and meet lots of great membrane biologists and microscopists. Many thanks to Davide Calebiro for hosting!

submitted 85 days ago • 0 comments

Is this not the finest lab crafted Christmas tree decoration you’ve ever seen? Courtesy of Amy Tooke!

submitted 87 days ago • 12 comments

Crosslinks can sometimes improve AlphaFold3 models. Crosslinking is an experimental method often used as a source of distance restraints in modeling. In AlphaFold3, instead of using restraints, crosslinks can be included as covalent ligands. Thanks to Agnieszka Obarska-Kosinska for the idea.

submitted 86 days ago • 3 comments

First attempt in a (loosely defined) Single-Molecule Biophysics starter pack. Please share and (self-) nominate. go.bsky.app/CteFZM5

submitted 107 days ago • 65 comments

Posting one of my favorite #organoid images for #microscopymonday. A 100+ day-old skin organoid with emerging hair follicles (ECAD, cyan) and endothelial cells (CD31, red). See: www.nature.com/immersive/d4.... Credit: Jiyoon Lee and Matt Steinhart from our lab. #devbio #stemcells

submitted 95 days ago • 10 comments

A complement to @peiferlabunc.bsky.social reposting this image – it was the cover of the 40th anniversary issue of J Neuroscience back in 2021, together with an historical review on imaging the neuronal cytoskeleton with lots of cool pictures: www.jneurosci.org/content/41/1...

submitted 95 days ago • 1 comment

I sometimes forget how flexible proteins are. It becomes really apparent when you use NMR states for an animation. That poor cofactor is getting pushed around a lot 😅 #sciart #blender3d #biocatalysis

submitted 95 days ago • 14 comments

I head someone explain this as “Good weird is being weird about your own business, bad weird is being weird about other people’s business” and I thought that summed it up pretty well.

submitted 95 days ago • 26 comments

We have two open PhD positions in my group at @crg.eu. We are seeking candidates with a background in computational and/or molecular biology, and with a broad interest in evolutionary biology, gene regulation, and comparative genomics. 📅Apply before January 12 here: www.crg.eu/en/content/t...

submitted 95 days ago • 1 comment

105 cool microscopists in this starter pack, but I know there are more out there! I want to find more 45 to complete the list, can you help me? 🤓🔬 go.bsky.app/Aaf8sKT

submitted 99 days ago • 54 comments

Thank feck for that. It's nice not to have to rub shoulders with fascists and scammers in order to find the latest papers

submitted 99 days ago • 0 comments

submitted 99 days ago • 5 comments

It is official! The fourth edidtion of our winter school on "Fluorescence markers for advanced microscopy" will take place on March 15-20 2026 in Les Houches, in the french Alps. fluorescenceleshouches.wordpress.com Selection of participants will start in 2025. Signup on the website to be informed.

submitted 99 days ago • 3 comments

Bacillus on the Blue place, starting small, but hopefully extending to keep the conversation active [it was also gorwing slow on Twitter] go.bsky.app/BfusVyD

submitted 101 days ago • 6 comments

Any more FFS/FCS Folks on bluesky? Where are you? Time to correlate. Please let me know who is on here and needs to be added. go.bsky.app/4BbiZyW

submitted 104 days ago • 3 comments

First experience with the eLife experiment - elifesciences.org/reviewed-pre... - constructive, high quality reviews that I will address soon in revision. Everything faster and more informative for readers than it would be if this were behind the scenes at a journal. What’s the drawback exactly?

submitted 239 days ago • 0 comments

Seems like its time for a re-introduction. I am a junior faculty at OHSU and a #teamtomo #cryoET enthusiast with a particular interest in membrane reorganization within mammalian cells. I develop the Surface Morphometrics toolkit (and some other bits and bobs).

submitted 105 days ago • 0 comments

Shots fired.

submitted 105 days ago • 23 comments

Here is a starter pack for CryoEM/ET enthousiasts To be completed go.bsky.app/JmQksC

submitted 112 days ago • 72 comments

Is this now happening for real? Are we acknowledging that SciTwitter transitions to BlueSci?!? 🤩 #bluesci #migration

submitted 105 days ago • 10 comments

go.bsky.app/KxWyLE4 Trying to put together a starter pack for journals!

submitted 105 days ago • 9 comments

We have a new lab website: roylelab.org The lab recently turned 18 years old 😮 and so it was time for a reboot.

submitted 105 days ago • 3 comments

The starter pack I made is at the 50/50 limit - I’ve heard many packs were expanded automatically to 150 people, any suggestions on how to make this happen? go.bsky.app/72NeGsT

submitted 106 days ago • 2 comments

Yesterday was the JOM, a special day in Swiss schools where students can spend a day with an adult at work to discover a job. I hosted our neighbors 10 yo girl in the lab to show her the job/life of a chemist. The good old trick of fluorophores and a laser beam never gets old, even for me 😊

submitted 105 days ago • 1 comment

I posted a while back about @cumsille.bsky.social ‘s lovely GenoVi software, but it really is great and makes lovely publication quality figures- recommend 5*s - GenoVi, an open-source automated circular genome visualizer for bacteria and archaea journals.plos.org/ploscompbiol...

submitted 105 days ago • 4 comments

Our lab now rocking in bluesky also =)

submitted 106 days ago • 2 comments

Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics. 14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell www.sciencedirect.com/science/arti...

submitted 107 days ago • 17 comments

Since there are more people on here now - can anyone help us with our hunt for a new autoclave? Cheers!

submitted 108 days ago • 1 comment

AlphaFold 3 model code and weights are now available from DeepMind github.com/google-deepm...

submitted 109 days ago • 7 comments

Making the lab smell delicious today, cooking up some caramel to make interesting sugar substrates with an MSci student! 🍬

submitted 109 days ago • 0 comments

For #MicroscopyMonday, here are cells taken at the scope with my daughter last year 🔬 🧪

submitted 109 days ago • 0 comments

Hi everyone! We study biophysics of bacterial cell wall division and growth using advanced light microscopy holdenlab.github.io #microsky #scisky #microscopy

submitted 109 days ago • 0 comments

I’m doing my best to keep Microbial Cell Bio Starter Pack updated. I’ve added some new people recently—so now’s a great time to update your follows and stay connected. If you’d like to be included in the pack, feel free to DM me! #Microsky go.bsky.app/L3L2iFz

submitted 109 days ago • 14 comments

Please repost: Nov. 15 deadline! We are building a strong bacteriology community at Univ de Montréal, including recent hires Sven van Teeffelen, Frédérique Le Roux & myself. Moving to Montréal in 2018 is one of the best career decisions I made. Come join us! jobs.sciencecareers.org/job/664282/a...

submitted 112 days ago • 1 comment

Join us! 4 Assistant/ Associate Professor posts available at University of Warwick School of Life Sciences, 2 in Host-Pathogen interactions and 2 in Plant Sciences: warwick-careers.tal.net/vx/lang-en-G... warwick-careers.tal.net/vx/lang-en-G... #microsky

submitted 112 days ago • 0 comments