sebpfeffer.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

xkcd.com/3056

submitted 7 hours ago • 0 comments

I hesitate to share this because I cringe at the sound of my own voice, but I must say that Chloe Aftel is a wonderful interviewer and made me comfortable despite this being a rather fish-out-of-water experience for me. theotherpod.com/newepisodes/...

submitted 1 day ago • 0 comments

In her Essay, Renata Basto highlights the huge budget cuts facing the scientific community in France. In response to the cuts, a group of researchers has formed the ‘Pour une Recherche d'Avenir’ initiative to secure the future of French research. journals.biologists.com/jcs/article/...

submitted 3 days ago • 2 comments

#VeilleESR #ESR Le lancement de la mobilisation du 7 mars pour défendre les sciences et la démocratie contre l'obscurantisme et les extrême-droites a eu lieu cette nuit. L'effort fait par des composantes diverses de la communauté scientifique pour s'unir est incroyable. standupforscience.fr

submitted 6 days ago • 2 comments

#Argonautes2025 update ... it will happen this August (27-30) @imgprague.bsky.social. Our ITs are finishing and testing the website, the registration will open on March 1st. More info will be provided later (once all speakers reply to my e-mail, just saying, not pushing 😁). Poster announcement:

submitted 16 days ago • 1 comment

We are looking for a #postdoc to discover cell-autonomous innate immune antiviral factors in mammals, based on newly-identified defense of prokaryotes! #EvoCure #comparativeImmunology #virology Please share @inserm.fr @ciri-lyon.bsky.social @cnrsbiologie.bsky.social ciri.ens-lyon.fr/teams/lp2l/j...

submitted 22 days ago • 0 comments

Hello, Bluesky! ☀️ We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late. Follow us for updates on ERC funding, research policy, and our grantees' discoveries.

submitted 22 days ago • 43 comments

A long post about what’s happening to the science funding agencies in the US and why. As mentioned, this one just kept getting longer even as I kept stripping curse words from it. www.science.org/content/blog...

submitted 24 days ago • 21 comments

Du 4 au 6 février 2025, personnels et étudiants sont appelés à voter pour élire leurs représentants. Qui vote pour quelles instances ? Quels sont les rôles des conseils ? Et l'équipe de présidence, est-elle nommée ou élue ?

submitted 29 days ago • 0 comments

Out today @ Science: TIR signaling activates caspase-like immunity in bacteria We report a new immune signaling molecule: N7-cADPR. Produced by phage-induced TIRs and activates a defensive bacterial caspase Congrats Francois Rousset, Ilya Osterman and coauthors! www.science.org/doi/10.1126/...

submitted 29 days ago • 1 comment

#SmallRNA pathways can regulate eukaryotic antiviral defense. This study in #Celegans shows that a subunit of the dREAM complex regulates antiviral RNAi in response to Orsay #virus infection; if mutated it can generate a constitutive state of antiviral readiness 🧪 @plosbiology.org plos.io/4hziGlf

submitted 29 days ago • 0 comments

#VeilleESR #ESR Le pdg du CNRS, A.Petit confirme dans un mail qu'il n'y aucun abandon des KeyLabs mais un délai de négociation "jusqu'à l'été", période défavorable à la mobilisation. Il réaffirme l'idée de différencier les laboratoires donc de fait d'en définancer une partie.

submitted 29 days ago • 4 comments

Dear all, registrations are open for the Mobile Genome @EMBO workshop. Many slots for posters, short talks but also long talks for last minute groundbreaking results! Let’s meet again on Nov 4-7, 2025 in Heidelberg. www.embl.org/about/info/c...

submitted 33 days ago • 0 comments

It’s a playbook and we are running out of time.

submitted 32 days ago • 19 comments

I think some people hear “grants” and think that without them, scientists and government workers just have less stuff to play with at work. But grants fund salaries for students, academics, researchers, and people who work in all areas of public service. “Pausing” grants means people don’t eat.

submitted 32 days ago • 1662 comments

Voici un exemple concret des conséquences du manque de crédit dans la recherche française. Nous avons deux microscopes électroniques de pointe à Bordeaux pour la biologie structurale et cellulaire. Faute de moyens suffisants, nous devrons très probablement arrêter l'un des deux instruments…

submitted 32 days ago • 6 comments

American science and medicine has been thrown into chaos and uncertainty over the past week. Here are some stories to get up to speed. 1/12

submitted 32 days ago • 64 comments

[ #VeilleESR #LPPR ] #KeyLbas : « un effet très déstabilisateur » « La direction [du CNRS précise] qu'elle n'a pas à obtenir l'aval du conseil d'administration pour les imposer. » Une politique discrétionnaire avec une mise en œuvre discrétionnaire, donc. www.francetvinfo.fr/sciences/rec...

submitted 33 days ago • 0 comments

Cliché parfait signé @afpfr.bsky.social

submitted 34 days ago • 2 comments

Extremely dangerous rhetoric here. Professors are the enemy, I want to fill the US (“America”) with babies, dismantling of institutions, placing cronies in charge of oversight mechanisms… This is an absolutists playbook

submitted 34 days ago • 2 comments

Après le NIH, c'est la NSF qui serait visée par la même interruption brutale d'activité. Catastrophe en cours.... Sinon, les keylabs et les 10% ponctionné sous forme de dîme et gabelle du CNRS sont de la gnognotte à côté non?

submitted 34 days ago • 1 comment

and don’t forget that Elon Musk FRS tweeted that Fauci should be prosecuted, recklessly stoking up the threat to him

submitted 35 days ago • 8 comments

Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X https://go.nature.com/42tH8Ai

submitted 36 days ago • 55 comments

Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors A 🧵 1/10 www.cell.com/cell/abstrac...

submitted 37 days ago • 1 comment

Sorry for the American research community. Things are not looking rosy in France either... Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring | Science | AAAS www.science.org/content/arti...

submitted 37 days ago • 0 comments

1/n So, this is out in NAR, finally. The longest, the most expensive and the most challenging project in the lab. Sparked by controversy concerning mammalian antiviral RNAi and our identification of Dicer variant, which is sufficient to increase RNAi. doi.org/10.1093/nar/...

submitted 39 days ago • 1 comment

submitted 38 days ago • 420 comments

📢Job alert We have two postdoctoral positions available, starting in Spring 2025. These positions are part of research funded by an ERC Advanced Grant, focused on exploring evolutionary immunology (Evo-Immuno). #Postdoc #InnateImmunity Do not hesitate to contact us. ibmc.cnrs.fr/en/laboratoi...

submitted 43 days ago • 0 comments

Ce matin, nous allons discuter du budget de l'enseignement supérieur et de la recherche. Le gouvernement va déposer un amendement visant à ponctionner 630 millions d'euros sur l'ensemble de la mission. Vous m'avez bien lu : 630 millions d'euros. La bataille va être rude.

submitted 40 days ago • 18 comments

Quelques explications complémentaires pour vous dire combien je suis furax en ce moment

submitted 44 days ago • 9 comments

Dear all, it was overdue to leave ex-Twitter and move to Bluesky. Happy to see that many of our old friends are here, too. We are attempting to connect to scientists interested in RNA biology and beyond. #translation #RNA #NMD

submitted 44 days ago • 1 comment

The editors @nature.com write a letter to Donald Trump on making US science thrive (unlikely to be read) www.nature.com/articles/d41...

submitted 44 days ago • 13 comments

The research community has flocked to the social-media platform Bluesky. Tell us about your experience https://go.nature.com/42fihQG

submitted 45 days ago • 11 comments

Time to share our organelle proteome paper out in @cellcellpress.bsky.social: doi.org/nzwz We created a spatial map of human cells using organelle immunoprecipitation at scale. Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/ 1/3 🧪

submitted 46 days ago • 7 comments

PLOS will no longer post on X/Twitter www.linkedin.com/posts/alison...

submitted 50 days ago • 3 comments

La face sombre du crédit d’impôt recherche #CIR #ESR Première niche fiscale pour les entreprises, le dispositif de soutien à la recherche et au développement attire les convoitises et les pratiques frauduleuses. www.lemonde.fr/economie/art...

submitted 50 days ago • 1 comment

“On behalf of the Berkeley Lab community, I extend my warmest congratulations to Jennifer for receiving the National Medal of Technology and Innovation. Her groundbreaking research will push the boundaries of science and benefit humanity.” - @mwitherell.bsky.social newscenter.lbl.gov/2025/01/07/b...

submitted 52 days ago • 0 comments

Des opposants à Jean-Marie Le Pen se rassemblent à travers la France pour célébrer son décès : « Ce sale raciste est mort »

submitted 52 days ago • 16 comments

🔥🔥🔥 Notre app #HelloQuitteX est sortie ! Récupérez vos followers de X en moins de 5 min, il suffit de récupérer votre archive X. Le #20Janvier, on vous reconnecte avec tous vos abonnés de X ! Yes we can ! Rejoignez ➡️ app.helloquitx.com Dessin de @cartooningforpeace.bsky.social

submitted 52 days ago • 5 comments

This tells you a lot about both the man who runs twitter and the people on it. At this point, the "we should be there because that's where the people are" argument feels increasingly like complicity, and participants more like collaborators.

submitted 54 days ago • 2 comments

Hi Bluesky, just in time for the holidays I am excited to share the latest pre-print from my group! We solved the 3D structure of a mysterious viral RNA that resists degradation by host nucleases. A short 🧵 &link below – please also check out the full video! #RNA #RNAbiology #RNASky #lovevirology

submitted 71 days ago • 8 comments

the Lai lab got a holiday gift ... so excited to share Seungjae Lee's work on surprising regulation of miRNA pathway at Science!! he did it all, from molecular genetics to biochemistry to genomics. and amazing collab with Makiko Yasuda lab brought it into mice. 1/3 www.science.org/doi/10.1126/...

submitted 71 days ago • 9 comments

RECRUITING-PhD student to study the role of RNA-binding proteins in antiviral defence during early development. #crispr #iclip #omics Interested candidates, please email a full CV and a statement of interest. Open to both UK and overseas www.findaphd.com/phds/project...

submitted 89 days ago • 0 comments

RNA sensing induced by chromosome missegregation augments anti-tumor immunity www.cell.com/molecular-ce...

submitted 71 days ago • 0 comments

RETRACTED: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial ALORS LA MES AMI.E.S ALORS LA www.sciencedirect.com/science/arti...

submitted 74 days ago • 12 comments

IT'S OFFICIAL! From today, @plos.org and its journals are no longer posting on Twitter/X. If you want to carry on hearing about great science in our journal, follow @plosbiology.org on Bluesky here: bsky.app/profile/plos...

submitted 74 days ago • 13 comments

We are looking for new group leaders. If RNA is your thing, and/or computational biology and you want to start your own group, check out these links. Feel free to contact me about these! And, please help me spread this. Thanks! www.imb.de/jobs/jobdeta... www.imb.de/jobs/jobdeta...

submitted 77 days ago • 2 comments

No doubt microRNAs play important roles in gene regulation and protein expression (ahem, Nobel Prize-worthy) but the literature is swamped by (IMHO) a ton of poor quality studies that pollute and dilute the field. Here's a preprint that may help clean things up. www.biorxiv.org/content/10.1...

submitted 78 days ago • 1 comment