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seeleyrj.bsky.social
H.K. Ransom Professor of Surgery at Univ of MI and director of MNORC. New treatments for obesity and diabetes via basic research.
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A new comprehensive review of GIP action from Professors Timo Müller and Matthias Tschöp et al, from discovery to modern day GIP-enabled medicines. Free to read via Molecular Metabolism #diabetes #obesity #islets #weightloss #incretin @helmholtzhzi.bsky.social www.sciencedirect.com/science/arti...

submitted 1 day ago • 0 comments

Our new paper shows that intraduodenal administration of Reg3g improves gut barrier function and mitigates hepatic steatosis in mice @seeleyrj.bsky.social journals.physiology.org/doi/abs/10.1...

submitted 2 days ago • 0 comments

And one more paper! Dr. Neil Blok shows the evolution of steatosis and fibrosis in mice on a MASH-inducing diet and the effects (or lack of) of housing temperature @seeleyrj.bsky.social journals.physiology.org/doi/abs/10.1...

submitted 2 days ago • 0 comments

A really good thread.

submitted 9 days ago • 0 comments

Next generation GLP-1 medicines for #weightloss Too much weight loss, too fast? @elaineywchen.bsky.social foreshadows experiences in the ongoing Retatrutide trials, and discusses broader implications for the field @statnews.com #obesity @matthewherper.bsky.social www.statnews.com/2025/02/20/t...

submitted 9 days ago • 0 comments

A little informal conversation from me about GLP-1-based therapies. medschool.umich.edu/department-n...

submitted 11 days ago • 0 comments

🚨 Job Alert ✨: Postdoc positions available in Daniela Cota’s lab in Bordeaux (France) and Sophie Croizier’s lab in Lausanne (Switzerland)! Do not hesitate to apply!!!

submitted 25 days ago • 0 comments

🚨 Applications are now open for this year's #CaswellDiabetes Clinical Translational Research Scholars Program! Are you an early-career scholar focused on diabetes research? Apply now to receive salary support, expert mentoring, and dedicated research time. 💙💛 diabetes.med.umich.edu/enrichment-t...

submitted 42 days ago • 0 comments

The scientist who is responsible for driving GLP-1 drugs for the treatment of obesity and testing them for prevention of Alzheimer's disease—Lotte Bjerre Knudsen— tells her story in a remarkable conversation. Full transcript, or video, all free, no ads. erictopol.substack.com/p/lotte-bjer...

submitted 55 days ago • 21 comments

Not sure I agree with all of this but worth a read when considering academic versus industry biomedical research settings. www.harvardmagazine.com/2025/01/harv...

submitted 70 days ago • 1 comment

SERVICE UPDATE We normally don't ask you to "share like and subscribe" but please distribute this. You are now able to delete the link after it embeds on your post so you can get those precious extra characters, and we will catch your post mentioning research. #AcademicSky #Medsky #HigherEd

submitted 80 days ago • 9 comments

A few minutes of me talking about our latest work on a GLP-1/leptin coagonist. Scroll down a little to find my interview. www.thenakedscientists.com/podcasts/nak...

submitted 84 days ago • 0 comments

30 yrs since its identification, leptin hasn't panned out as a treatment for obesity — but could it play a role in strengthening GLP-1 treatments? A mouse study by @seeleyrj.bsky.social out in Science Translational Medicine says it might be 🧪 www.statnews.com/2024/12/04/l...

submitted 86 days ago • 0 comments

ubc.wd10.myworkdayjobs.com/en-US/ubcfac... We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.

submitted 86 days ago • 1 comment

Latest from our group in collaboration with Lotte Bjerre Knudsen and other Novo scientists. They developed a GLP-1/Leptin co-agonist that we put through its paces in a number of mouse models to prove that both parts of the molecule matter. More options on the table! www.science.org/doi/10.1126/...

submitted 86 days ago • 2 comments

www.keystonesymposia.org/conferences/... this is the better link

submitted 87 days ago • 0 comments

Not sure who cares about this but it is a really interesting effect of a GLP-1 agonist. Work took us a LONG time to do.

submitted 89 days ago • 0 comments

Our latest work to understand the dynamics of brain GIP and GLP-1 signaling to mediate responses to pharmacotherapy for obesity. Replicates key work from Timo Mueller and lab at the Helmholtz and takes it a little farther. www.sciencedirect.com/science/arti...

submitted 94 days ago • 0 comments

A fun thing nobody tells you about a career in science is how much of your life will be spent waiting for mice to have sex

submitted 95 days ago • 6 comments

This is a good opportunity for the right person. I can recommend it.

submitted 96 days ago • 0 comments

🚨 Tenure track positions at Physiology Dept UMN. Join a vibrant research environment: med.umn.edu/physiology med.umn.edu/aging med.umn.edu/about/center... Areas of interest: aging biology, molecular metabolism, cardiovascular, inflammation, stress etc. Apply here: z.umn.edu/9zxj

submitted 98 days ago • 0 comments

Please share! Join us at #OhioState in Columbus for 2 days of great metabolism science! Feb 21 - Preventative Heath of Adipose Tissue (PHAT; 4th annual) and Translational Research in NeuroMetabolism Symposium (TRINS; 3rd annual); Feb 22 6th BTAA Lipids conference! Registration tinyurl.com/3x4bpbkf

submitted 99 days ago • 0 comments

I've been attending the Society for the Study of Ingestive Behavior (SSIB.org) conference since 1996 as a grad student, pdoc, prof and I now have the honor of serving as its President. Its an exceptionally warm group of scientists. Join us in Oxford UK on July 28 for the 2025 meetng!

submitted 103 days ago • 0 comments