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semilc.bsky.social
Scientist @UCSF studying cell fate specification, transcription factors and motile cilia. Food and dog take up the rest of my time.
8 posts 1,156 followers 621 following
Regular Contributor
Posts 15 Comments 6

A reminder to colleagues interested in Cell-Matrix adhesion & anything ECM related that registration is now open for the Fibronectin, Integrins & related molecules Gordon Research Conference. Incredible list speakers! incredible location! it will 🔥 🔥 🔥 Please join us! www.grc.org/fibronectin-...

submitted 34 days ago • 0 comments

Are you a trainee interested in cilia? Or mucus? Or mucocliloary interactions? Register for the GRS (www.grc.org/cilia-mucus-...)! We are selecting talks for the cilia session soon, so submit your abstracts asap to be considered!

submitted 53 days ago • 0 comments

Are you a trainee interested in cilia? Or mucus? Or mucocliloary interactions? Register for the GRS (www.grc.org/cilia-mucus-...)! We are selecting talks for the cilia session soon, so submit your abstracts asap to be considered!

submitted 53 days ago • 0 comments

Delighted to share our new preprint on the cell biology and genome of Stentor pyriformis, a giant ciliate that maintains Chlorella endosymbionts in surface-associated microtubule baskets. www.biorxiv.org/content/10.1...

submitted 66 days ago • 12 comments

Cilia alert! Stoked for our new paper in Dev. Cell! Our cross-linking mass spec interactome for motile cilia provides some cool new insights into motile ciliopathy. Helmed by @computingcaitie.bsky.social, read her fantastic Bluetorial below (👇)! www.cell.com/developmenta...

submitted 71 days ago • 0 comments

I am excited to share some of my PhD work on the motile cilia interactome revealed by XL/MS with @jbwallingford.bsky.social @edwardmarcotte.bsky.social Ophelia Papoulas, Chanjae Lee, David Taylor, and @builab.bsky.social www.cell.com/developmenta...

submitted 71 days ago • 4 comments

Super excited to announce my new lab at the University of Michigan opening Jan 2025! 🎉We’ll study how cells work together to shape the GI tract, with ties to regeneration & disease. Hiring at all levels—esp. a research tech to help launch the lab! Info: huyckelab.org #DevBio #CellBio #Hiring

submitted 74 days ago • 12 comments

Check out our new ✨preprint ✨📝 describing extraordinary convergence of autism proteins at the cilium, a 🧵 www.biorxiv.org/content/10.1... (1/ )

submitted 78 days ago • 2 comments

Out today, our newest paper in Nature Cardiovascular Research! A Herculean effort by an amazing grad student Joanna Wong. In short, we demonstrate pulmonary veins sprout and differentiate into capillary cells after severe lung injury. www.nature.com/articles/s44...

submitted 78 days ago • 4 comments

My first post on Bluesky. Check out the paper with my colleague Moe Mahjoub on expansion microscopy in kidneys dx.doi.org/10.1002/cm.2...

submitted 98 days ago • 1 comment

🧪 Lab's latest!! Work by PD (and now PI) Alison Philbrook. C. elegans sensory neurons have gorgeous #cilia. We’ve always thought that a) no cilia = no sensory responses, & b) no IFT = no cilia. Punchline is we thought wrong. Read paper for more! #neuroscience journals.plos.org/plosbiology/...

submitted 91 days ago • 11 comments

Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)

submitted 91 days ago • 15 comments

This just out from grad student Samantha Bromley-Coolidge with help from Regis University undergrad Diego Iruegas. By the way, Regis has an awesome neuroscience program. If one of their students applies to your grad program, give them a close look! authors.elsevier.com/a/1k7nr14Yy4...

submitted 97 days ago • 1 comment

Check out this airway organoid stained for cilia (red) and a transcription factor, FOXJ1 (cyan), dedicated to generating motile cilia. This organoid was grown from mouse airway stem cells using a protocol developed by Brigid Hogan's lab (Rock et al., PNAS 2009).

submitted 98 days ago • 0 comments

Airway multiciliated cells make hundreds of centrioles (cyan) each of which extends a motile cilum (🔥). These cilia beat to move mucus and keep your lungs clear of dust, viruses and bacteria.

submitted 101 days ago • 0 comments