Profile avatar
shaunmahony.bsky.social
Studying gene regulation and transcription factor binding with machine learning. Assoc Prof at Penn State. 🇮🇪
311 posts 1,441 followers 649 following
Regular Contributor
Active Commenter

By crushing cancer research, what are Elon & Trump making more efficient? Their NIH funding cuts are illegal—so instead, they're suffocating the grant approval process for cancer researchers with so much red tape that labs & clinical trials will be forced to shut down.

🎆Next #FragileNucleosome meeting is less than a week away! We are delighted to host @manucazottes.bsky.social, @robertadolling1.bsky.social & @leandrosboukas.bsky.social ! We will discuss evolution of XIST regulatory network, cancer epigenetics, and MDEMs! 🗓️ us06web.zoom.us/webinar/regi...

🚨PA colleagues: "Senator Fetterman wants to hear from you about how the federal funding freeze is affecting Pennsylvania." "If your project has been impacted, please fill out our constituent impact form:" forms.office.com/g/mFv2JAPxpC Get out your Other Support and share that info!

NIGMS MIRA explicitly asks for the following in investigator biosketches: “Include descriptions of significant service to the scientific community that are beyond normal mentoring and committee duties expected at the PD's/PI's institution.” They can’t then punish a PI based on the type of service

Another school curtails admissions, even offers already made. This is on #Trump, #Musk and #Vought. Time to fight back. www.thedp.com/article/2025...

The University of Pittsburgh confirmed Friday that there would be no new Ph.D. offers of admission while Pitt works to understand how reduced federal aid could impact the institution.

Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget. https://go.nature.com/4gM6oW4

It looks like 8/8 study sections that were scheduled to begin today have been cancelled: www.csr.nih.gov/RevPanelsAnd...

Are other outlets covering this? It's effectively another freeze on NIH funding. By my count, 3/8 study sections were cancelled today, 4/8 are cancelled tomorrow. Will only get worse as we hit those that were not posted before 1/20 @zey.bsky.social ? www.thetransmitter.org/funding/fede...

JD Vance has expressed a “deep hostility to the entire academic enterprise, not just the so-called woke parts,” writes @michellegoldberg.bsky.social. "He wasn’t talking about making more room for right-wing ideas in universities or even dreaming of taking them over. He wanted to destroy it all."

Bluetorial: The rationale for the “NIH” indirect cost “plan” is based on misunderstood (unintentional or intentional) accounting and math The value of real government transparency

Here's a quantitative illustration of what's happening with NIH funding.

Greenland famously acquired its name as a marketing tool to get viking settlers to move there. I'm fine with the new name if it encourages certain people to move there too

What's the indirect rate at SpaceX? Tough to answer, since they're not reqd to publicize indirect rates like universities. BUT, the cost of a Falcon9 launch is $100M for US gov't and $67M for a private company. So the ADDITIONAL overhead that SpaceX charges for working with the US gov't is 50%.

Many in biotech/private sector are boasting about their ways of funding and doing science But they are staffed with PhDs and postdocs we train in our NIH and NSF funded labs in universities With university labs lacking funds to train, the private sector will be profoundly harmed

"Every $100 million in investment leads to 78 patents and $598 million in further research, according to N.I.H. calculations" Or $100 million will get the taxpayer one Falcon 9 launch with SpaceX www.nytimes.com/2025/02/11/o...

This is an excellent article that accurately describes the situation with NIH funding. Great work @zey.bsky.social ! www.nytimes.com/2025/02/11/o...

Did you all know that SpaceX charges the US Gov't $100M per Falcon 9 launch, even though the rocket costs them as low as $15M? But Elon would have you believe that cancer researchers at non-profit universities are the ones milking the system.

We should talk more about where the US gov't gets huge value for taxpayer money. Take NIH study section: they get 25-30 expert PhD consultants to each spend 40-50 hours scrutinizing grant apps (incl 2 solid days of group discussion) and they pay them ~half of DC minimum hourly wage. And no coffee

It certainly is NOT just a higher ed issue. My company exists today because of the NIH SBIR program. At a 15% indirect rate, that money won't support the research it supposedly funds. My company would not have existed, and would not be supporting drug discovery and development worldwide today.

#BREAKING - 22 states sue to block Trump administration cuts to NIH research payments