smlea.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

smlea.bsky.social

Scientist at the NCI Frederick using structural biology to try and understand how things work - views are my own not my institutions

12 posts 1,580 followers 1,603 following

Posts 22 Comments 13

Less than half an hour ago, a peaceful transfer of power has taken place at #BPS2025! Join me in welcoming Madam President of the @biophysicalsoc.bsky.social, Professor Lynnmarie Thompson! And Madam President Elect, Professor Karen Fleming! 👏👏👏👏👏

submitted 10 days ago • 1 comment

A new structural paradigm for outer membrane protein biogenesis in the Bacteroidota https://www.biorxiv.org/content/10.1101/2025.02.17.638638v1

submitted 10 days ago • 0 comments

Hive mind: I seem to remember having seen a plot/analysis showing that pLDDT is correlated to conservation but my mind or Google-fu isn’t finding it

submitted 42 days ago • 3 comments

It is a great honour to invite you to a symposium to celebrate the career of Mark Carrington. An exciting set of talks, particularly if you are fascinated by trypanosomes.

submitted 46 days ago • 0 comments

1/ Thrilled to announce Dr. Elizabeth Wright as the inaugural winner of the June Almeida Award for #cryoem! 🎉Elizabeth’s pioneering work in both cryo-ET methods and structural virology made her a perfect fit for this award. Congrats, Elizabeth!

submitted 73 days ago • 1 comment

19F modified amino acids such as trifluoromethyl-Phe integrated into proteins can give strong, clean signals for complex samples, but the results are difficult to interpret in terms of structure This study uses "ring current design" to increase 19F chemical shift dispersion and interpretability 🧬🧶🧲

submitted 73 days ago • 0 comments

Americans are now one-third less likely to die from cancer at the same ages as Americans in 1990

submitted 81 days ago • 4 comments

Clap in the face reminder when judged on PhD/post doc years even after >12 years: "Kovacs' record in microbiology is somewhat lighter, particularly early career lack of first-authored leadership on high level publications" ... and I am still in academic science #nevertheless

submitted 96 days ago • 4 comments

Phages! At the Disco! Here's Ellie (the first author's) thread on our new preprint on how to discover weird new phages using glowing bacteria:

submitted 97 days ago • 4 comments

Visiting @arianebriegel.bsky.social at the Institute Pasteur ! Great to see her new lab!

submitted 98 days ago • 2 comments

We will be hosting 3rd Full Circle Symposium for Native Biologists hosted at UCSF in April 2025! We aim to build community and provide meaningful opportunities for Native scientists. If you are a Native biologist who is interested plz fill this out to stay up to date: forms.gle/AN7nfkhdB3Fv...

submitted 102 days ago • 1 comment

I am about to be recruiting two post-docs to work on cryoEM and cryoET of amyloid aggregates... Anyone interested please drop me a line while the wheels of our HR department turn.............

submitted 102 days ago • 0 comments

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

submitted 105 days ago • 1 comment

Published today Steve and Justin’s story that finally reveals the basis for transmission of uni directional ion flow into bi-directional rotation of the bacterial flagellum doi.org/10.1038/s415...

submitted 357 days ago • 0 comments

Important so please help spread the word... Interested in postgrad research? Maybe do a PhD? Oxford runs a summer internship scheme for UK students from under-represented and disadvantaged backgrounds Stipend, free accommodation, mentoring... Deadline 21 Feb www.ox.ac.uk/admissions/g...

submitted 410 days ago • 0 comments

Time for puppy to start sciencing….

submitted 421 days ago • 1 comment

For microbiologists seeking faculty jobs: Rutgers has 4+ faculty searches in microbiology right now! Please share widely and see below for details and links on the individual positions 1/5

submitted 471 days ago • 1 comment

A fantastic postdoc opportunity with Jon Grimes at Strubi, University of Oxford, to study the molecular mechanisms of viruses using the latest cryo-ET and cryo-SIM technologies. my.corehr.com/pls/uoxrecru...

submitted 479 days ago • 0 comments

The Dunn School at University of Oxford just can't stop recruiting! This time an Associate Prof in cell/mol biology with focus on infection, immunology, inflammation Come and join us... Please spread the word www.path.ox.ac.uk/vacancy/asso...

submitted 479 days ago • 0 comments

Can we please use the term machine learning in scientific publications and not AI? The first is a set of mathematical methods that can be analysed and criticised, the second a divisive buzzword. 🧪 #AcademicSky

submitted 498 days ago • 1 comment

Come work in my lab in Oxford Biochemistry- Postdoc funded via HECBioSim (EPSRC) in collab with Arvind Ramanathan at Argonne National Lab. We will do massive bacterial membrane simulations augmented with ML. We are friendly, supportive lab in a beautiful city. www.jobs.ac.uk/job/DDF342/p...

submitted 502 days ago • 0 comments

Come be my colleague! The MCB Department at UConn is looking for a TT Assistant Professor in the broad fields of structural biology, biophysics, and biochemistry. Collaborative department, strong graduate program, and state of the art core facilities. academicjobsonline.org/ajo/jobs/25945

submitted 520 days ago • 0 comments