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sschandelmaier.bsky.social
Health research methodologist, methods guidance & implementation, meta-science. www.LIGHTS.science @lightsdatabase.bsky.social www.ICEMAN.help @clinepi-basel.bsky.social
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I’m thrilled that leading research groups now recommend our #ICEMANtool to evaluate possible subgroup effects: #Cochrane in their handbook Chapter 10.6 #GRADE in their guidance No. 36 Germany's #IQWIG in their general methods www.iceman.help www.cmaj.ca/content/192/...

Ian Fleming's original James Bond novels haven't aged well. For example, Moonraker - published almost exactly 70 years ago in April 1955 - features a villain who's a super-rich industrialist and rocket-maker seeking to cause chaos because he's a secret Nazi. Such a silly idea!

Hi @bmj.com Can you add a Bluesky share button instead of the X button you have please?

Time to evict AirBnB from your life, if you have't already.

Have you checked our risk-stratified #RapidRecs on #PCSK9 inhibitors and #ezetimibe for the reduction of cardiovascular events ? @magicevidence.bsky.social @bmj.com -->https://www.bmj.com/content/377/bmj-2021-069066

The risks of backing scattered islands of sensible points in a sea of nonsense: kucharski.substack.com/p/islands-of...

www.thelancet.com/journals/lan...

J Clin EPi @jclinepi.bsky.social has a unique focus on meta-research. I've co-led a November editorial reflecting on the variety its content, and how an even richer balance might be achieved. Methodologists assemble! www.jclinepi.com/article/S089... @davidit.bsky.social @andreatricco.bsky.social

So true!

Happy New Year! I wrote a list of numerical coincidences involving 2025, see if you spot something fun! #MathsSky #MathSky #MathsToday #MathChat

www.ted.com/talks/jimmy_...

Ever wonder about the basis for fear-mongering & conspiracy theories about mRNA vax? Wish you had a place to go when someone cites "proof"? I've got you covered! In my latest @plos.org I buckle up for the waves of anti-vax muck likely to come in 2025. 1/2 absolutelymaybe.plos.org/2024/12/28/g...

1/ Excited to share thoughts on two excellent blog posts about clinical trials! First up: "The Case for Clinical Trial Abundance" by @ruxandrabio.bsky.social and Willy Chertman . They argue we need more clinical trials & that bureaucracy hampers faster progress. A sentiment I fully share!

Vaccines stopped polio.

Methods guidance is evolving. Here the authors chose to provide explicit recommendations both in favor but also agains certain methods. I think that that’s the way forward!

Does #randomization ensures balance of risk factors between groups? Consider this: In Denmark 860 individuals were randomly allocated to either intervention or control. Individuals were unaware of their allocation. No intervention took place. Mortality was higher in the intervention group (p=0.003)

This is leadership

Launching this week, MetaROR will be a free, open platform where anyone working with metaresearch can share their work and receive transparent, open peer reviews. Join us at one of our launch events to find out more: researchonresearch.org/metaror-laun...

A podcasting highlight! Thanks so much to Editor-in-Chief of Science @holdenthorp.bsky.social for such a generous interview - calling for increased HPS teaching across high school and uni science curricula Check the ep out on the pod today! #hps #sts #histstm #philsci #academicsky #metasci

What a talent. RIP Quincy Jones.

Hi qualitative researchers! For my teaching, I was searching for something like PICO for qualitative. I found SPIDER and like it! pubmed.ncbi.nlm.nih.gov/22829486/ Is anybody aware of any other scheme for systematic question / problem / objective formulation in a qualitative study?

For patient-focused research, there are very few useful research aims, and none of them are "identifying risk factors.” Seriously! 😜 (ICYMI) statsepi.substack.com/p/sorry-what...

Did you just present new #TrialsMethodology guidance at #ICTMC2024? Have a look at our new database and check whether it is already in it. If not, send it along! lights.science