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sshaolab.bsky.social
Dissecting molecular mechanisms that regulate protein and cellular homeostasis. https://shao.hms.harvard.edu
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Cup? Platter? Stained glass? Our imaginations were inspired (even during uncertain times!) by these beautiful molecular complexes: the Erlin and prohibitin complexes implicated in quality control at the ER and mitochondria, respectively. Check them out here: www.biorxiv.org/content/10.1...

My father-in-law, Jack Strominger, and I wrote a letter to the @wsj.com editor about the current threats to science due to Trump's funding freeze. Please repost! www.wsj.com/opinion/scie...

How do cells achieve an optimal mitochondrial distribution? Excited to share a piece of this puzzle: www.science.org/doi/10.1126/...

~1 week left to register for the EMBO workshop on RNA meets protein decay! #EMBOrnaDecay Come join us for a fun time and invigorating scientific discussions in Vienna! meetings.embo.org/event/25-rna...

Amazing meeting last week in Germany: 130th International Titisee Conferences on Stress Signalling in Development and Disease organized by Brenda Schulman & @micharapelab.bsky.social !

My thesis work on codanin-1/CDAN1 and the histone chaperone ASF1 is officially out! Take a look here:

@samanthasedor.bsky.social's pet project taking us into completely new directions is out in print form! rdcu.be/edKuA

Check out these insights into (and the importance of) delivering ubiquitin-independent proteasomal substrates for degradation in the nucleus!

Congratulations to our own Spyros Artavanis-Tsakonas for recieving the Wiley Prize for his work on the Notch Signaling pathway! We deserved recognition for a pioneer in developmental biology. newsroom.wiley.com/press-releas...

Join me, @talleylambert.bsky.social, @bethcimini.bsky.social, @florianjug.bsky.social & Hunter Elliott for our two week CSHL course on microscopy & image analysis starting March 24, 2025! Applications are due 1/31/25. meetings.cshl.edu/courses.aspx...

A reminder that the Brown lab has an opening for a postdoc fellow: brown.hms.harvard.edu/jobs/242. This might suit someone from the #cilia community interested in learning structural biology. Deadline extended to the 10th Jan.

Introducing Dr. Samantha Sedor! #PhDone

So many things happen on proteasomes! It was fun to dig into how a the active thioreductase TXNL1 engages the regulatory particle! www.biorxiv.org/content/10.1...

Happy to be making our first post on bluesky - a photo from our recent departmental retreat. Looking forward to sharing new discoveries and news from our trainees and faculty, as we continue to build a cell biology community here - check us out at cellbio.hms.harvard.edu

A small molecule degrader of the translation termination factor eRF1 = a metal-dependent molecular glue on ribosomes Learn more here! rdcu.be/du2ZX

Check out the protein compartmentalization and sorting minisymposium at #cellbio2023 today starting at 3:30 pm in Room 254A!