steinaerts.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Welcome to Leuven and vib.ai Joana, we've all been looking forward to this day! Now the fun can start and the protein universe shall reveal its secrets :)

submitted 18 hours ago • 0 comments

Congrats Camiel, awesome to have you in the lab!

submitted 18 hours ago • 0 comments

Congratulations to Camiel Mannens, postdoc in the Aerts lab, on obtaining an MSCA fellowship to investigate how genes control brain cell types across different species. 👏

submitted 18 hours ago • 0 comments

📢 Bring your computational expertise to our cutting-edge research team at @embl.org! Join us together with experts from GSK to explore the effects of rare variants using population-scale cohorts and single-cell readouts. Please share 🙏 🔗 Apply now: embl.wd103.myworkdayjobs.com/de-DE/EMBL/d...

submitted 9 days ago • 0 comments

Happy 600th birthday to the University of Leuven!

submitted 11 days ago • 0 comments

The latest Discover ASAP episode dives into "Cell Type Directed Design of Synthetic Enhancers," a study published in Nature by CRN Team Voet. They discuss how machine learning enables precise enhancer design for targeted gene expression 🧬 Watch: www.youtube.com/watch?v=Qcms...

submitted 13 days ago • 0 comments

To US colleagues who have lost or are in imminent danger of losing their jobs: please DM whether we can accommodate your research.

submitted 11 days ago • 5 comments

🧠 Exploring 300 million years of brain evolution through the lens of enhancer codes, by @niklaskemp.bsky.social @steinaerts.bsky.social, Nikolai Hecker @science.org @vibai.bsky.social @cbdresearch.bsky.social @fwovlaanderen.bsky.social @chanzuckerberg.bsky.social @erc.europa.eu 👉 vibbio.tech/3QDWhbn

submitted 12 days ago • 0 comments

Deep learning provides new view on 300 million years of brain evolution phys.org/news/2025-02...

submitted 12 days ago • 0 comments

There's still a few free spots on Sunday

submitted 12 days ago • 0 comments

This has been a fantastic adventure - to capture the genomic regulatory code underlying brain cell types (using deep learning models trained on chromatin accessibility), and then use these models to compare cell types between the bird and mammalian brain

submitted 12 days ago • 4 comments

Just very happy to have our paper out today! A big thanks to all our co-authors, and to Nikolai and @steinaerts.bsky.social for the teamwork over the past years. If you are interested in using our models for cross-species enhancer studies, check out crested.readthedocs.io/en/stable/mo... 🙂

submitted 12 days ago • 3 comments

In a new study, Nikolai Hecker, Niklas Kempynck et al. in the team of @steinaerts.bsky.social explore 300 million years of brain evolution through the lens of enhancer codes. www.science.org/doi/10.1126/...

submitted 12 days ago • 1 comment

Our article on the evolution of pallial circuits is out www.science.org/doi/10.1126/... 🥳 Eneritz Rueda-Alaña & Fernando García-Moreno led this study that proves how similar adult pallial neurons are generated in different regions and timepoints. Evolutionary CONVERGENCE of neurons & circuits! 🦎🐤🐭

submitted 12 days ago • 2 comments

Three fantastic @science.org papers on convergent development & evolution of neurons + their connections in the bird & mammalian pallia, by @kaessmannlab.bsky.social @steinaerts.bsky.social & Fernando García-Moreno. Expertly synthesised by @giacomogattoni.bsky.social & Maria Antonietta Tosches 🧪🧠

submitted 12 days ago • 2 comments

And please check out the wonderful Perspective by Maria Tosches and Giacomo Gattoni on our paper and the two related ones by the groups of @steinaerts.bsky.social and Fernando Garcia-Moreno!! www.science.org/doi/10.1126/...

submitted 13 days ago • 0 comments

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

submitted 18 days ago • 86 comments

I have big news: @ellis.eu has launched its 2nd major research center, @ellisfinland.bsky.social! I have agreed to start as founding director & the first call for PI positions is open. This is a major opportunity for outstanding researchers, join us! ellisinstitute.fi/PI-recruit

submitted 22 days ago • 2 comments

On Wed., Pedro @pedrotomazdasilva.bsky.social talks about interpreting DNA Language models through nucleotide dependency analyses. Capturing functional interactions -maps like this one for an intron- and more: RNA structures, reg motifs,... preprint: www.biorxiv.org/content/10.1...

submitted 23 days ago • 0 comments

The Genomic Code: The genome instantiates a generative model of the organism arxiv.org/abs/2407.15908 (revised version, following peer review)

submitted 40 days ago • 8 comments

We share a lot of our ideas, code, datasets (that we spend years sanitizing) early. Often way before we release preprints. We do this so that others can use, build on, improve & even "beat" our approaches. But I want to say a few things about some simple expectations 1/

submitted 40 days ago • 1 comment

Fantastic opportunity: 🚀 Calling early-career scientists! Apply for the 2025 ELISIR Scholar at EPFL. From outstanding PhD straight to group leader. Join an interdisciplinary research community to conduct independent research in any area of #lifesciences in Lausanne, CH 👉 go.epfl.ch/ELISIR

submitted 47 days ago • 0 comments

Congrats to Johannes Linder, David Kelley et al. on the journal publication of Borzoi - a long context sequence models of RNA-seq coverage profiles with many nice applications for transcriptional & post-transcriptional regulation & variant effect prediction. www.nature.com/articles/s41... 1/

submitted 49 days ago • 2 comments

Very excited to announce that the single cell/nuc. RNA/ATAC/multi-ome resource from ENCODE4 is now officially public. This includes raw data, processed data, annotations and pseudobulk products. Covers many human & mouse tissues. 1/ www.encodeproject.org/single-cell/...

submitted 50 days ago • 6 comments

Our ChromBPNet preprint out! www.biorxiv.org/content/10.1... Huge congrats to Anusri! This was quite a slog (for both of us) but we r very proud of this one! It is a long read but worth it IMHO. Methods r in the supp. materials. Bluetorial coming soon below 1/

submitted 63 days ago • 8 comments

Introducing Flashzoi⚡! We’ve upgraded the Borzoi model with rotary pos. encodings and FlashAttention, resulting in a significant speedup with similar or better accuracy for faster variant effect prediction, quicker model development and more efficient genomic analysis www.biorxiv.org/content/10.1...

submitted 65 days ago • 1 comment

Flashzoi: An enhanced Borzoi model for accelerated genomic analysis https://www.biorxiv.org/content/10.1101/2024.12.18.629121v1

submitted 67 days ago • 0 comments

We are thrilled to announce that IRL JEDI meetings will restart in 2025. You can already register at flyjedi.sciencesconf.org where you'll find a preliminary program. Looking forward to meeting you and restart this network of fly people!

submitted 68 days ago • 0 comments

Finally out! We present EXTRA-seq, a new EXTended Reporter Assay to quantify endogenous enhancer-promoter communication at kb scale! www.biorxiv.org/content/10.1... A 🧵about what it can do: #SynBio #DeepLearning #GeneRegulation

submitted 72 days ago • 5 comments

Check out this systematic benchmark of genome-wide, annotation agnostic DNALMs & strong baseline ab-initio models for biologically meaningful tasks in regulatory genomics 1/

submitted 78 days ago • 5 comments

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

submitted 85 days ago • 479 comments

Genome Biology is calling for submissions to our Collection on Regulatory elements in plants. Guest Editors: - Pil Joon Seo, PhD, Seoul National University, South Korea - Klaas Vandepoele, PhD, Ghent University, Belgium More info: www.biomedcentral.com/collections/... please RT

submitted 85 days ago • 0 comments

🚨 We're hiring! Join the University of Antwerp as a Postdoc in Molecular AI. 🔬 Develop AI for billion-scale metabolomics data & explore small molecules as life's building blocks. 📍 Antwerp, Belgium 🗓️ Apply now: bit.ly/4gpl4e7 #PostDoc #Metabolomics #ResearchJobs #MolecularAI #vacancy #bioinformatics

submitted 91 days ago • 1 comment

last couple days to apply (for free! from anywhere in the world!) to the Sanger 2025 PhD Programme — Deadline: 28th November 2024 (09:00 GMT) For more info, visit www.sanger.ac.uk/about/study/...

submitted 93 days ago • 0 comments

We have two open PhD positions in my group at @crg.eu. We are seeking candidates with a background in computational and/or molecular biology, and with a broad interest in evolutionary biology, gene regulation, and comparative genomics. 📅Apply before January 12 here: www.crg.eu/en/content/t...

submitted 93 days ago • 1 comment

Abstract submissions are still open for the CSHL Network Biology meeting in March 11 - 15 2025 (abstract deadline: Jan 10). A large fraction of talks will be selected from the abstracts. On behalf of the organizers, we look forward to welcoming you there. meetings.cshl.edu/meetings.asp...

submitted 92 days ago • 1 comment

Computational methods in biology opened a new world of insights and breakthroughs. 🌍 🖥️ EMBL has been at the forefront of innovations which have propelled the field forward and opened up access to bioinformatics data and resources for the entire scientific community. 🧬 www.embl.org/news/science...

submitted 92 days ago • 2 comments

Introducing scE2G: a new model to link enhancers to target genes using single-cell data. Excited that scE2G will enable building enhancer maps in hundreds of cell types in the human body! Wonderful collaboration with @randersson.bsky.social @613weilin.bsky.social @mayayayas.bsky.social Thread👇

submitted 93 days ago • 0 comments

Good morning! Ready to welcome you at #VIBAIsymposium.

submitted 98 days ago • 0 comments

We close the day with beers and... snow! 🍻❄️ Thank you to all the speakers for their fantastic talks, sponsors for their support, and all participants for joining! See you at the next edition! #VIBAIsymposium

submitted 98 days ago • 0 comments

Congratulations to Thomas Guiziou (VIB-VIB Center of Structural Biology) and Tom Luijts (Cancer Research Institute Ghent), who won the awards for the two best posters of the day! 👏 #VIBAIsymposium

submitted 98 days ago • 0 comments

Full house and a filled schedule today. Some snapshots of the last session of the day, with talks by @benlehner.bsky.social, David Kelley and Tanja Kortemme. 📸 #VIBAIsymposium

submitted 98 days ago • 0 comments

Fantastic start of the #VIBAIsymposium this morning with a welcome by our scientific director @steinaerts.bsky.social and talks by Julien Gagneur and @avsecz.bsky.social

submitted 98 days ago • 0 comments

My goal is to understand the regulatory role of every nucleotide in the genome, and how this changes across every cell in the human body. If you are interested in doing a Ph.D. with me at UMass Chan Medical (Genomics and Comp Bio Department), see the links below. Deadline is Dec 1st.

submitted 100 days ago • 7 comments

Join the Pereiralab at vib.ai 👇

submitted 102 days ago • 0 comments