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Microvessel (purified from rat adipose) - #hiPSC-cardiomyocyte cotransplantation🫀 👉>100-fold⏫hiPSC-CM engraftment 👉⏫heart functional recovery in Diabetic rat MI #T2D A potential role of #Angiocrine IL6🤠 @saravasconcelos.bsky.social @stemcellreports.bsky.social 2025 www.cell.com/stem-cell-re...

submitted 7 days ago • 1 comment

Cell Fate Changes – Transcriptional Memory in Reprogramming Dr. Eva Hörmanseder, #HelmholtzMunich & team uncovered why some cells resist reprogramming – a key hurdle for regenerative medicine. 👉 t1p.de/43yrw @epihmgu.bsky.social #CellReprogramming #Epigenetics #StemCells #RegenerativeMedicine

submitted 5 days ago • 1 comment

Reprogramming efficiency varies across cell types in vivo and is modulated by somatic cell identity memory. Eliminating somatic cell transcriptional memory improves reprogramming success #nucleartransfer ow.ly/g1Au50VimTM @www.helmholtz-munich.de @isscr.org

submitted 21 hours ago • 0 comments

hiPSC-derived myofibers with m.3243A>G mutation show impaired #mitochondria bioenergetics, and increased NADH/NAD+ ratio and PI3K/AKT/mTORC1 activation by metabolic rewiring #mtDNA ow.ly/18rt50Vimyc @ucl.ac.uk @isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social @cellpress.bsky.social

submitted 1 day ago • 0 comments

New study shows genetic variation affects DNA #hypomethylation & imprint deregulation in naïve PSCs. Genetic variants may be potential biomarkers for epigenetically stable PSCs. ow.ly/aCVY50VilVY @isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social

submitted 4 days ago • 1 comment

🚨NEW PAPER ALERT! 3 of our teams at IES collaborated to understand why some cells reprogram effectively while others fail @hamperllab.bsky.social @antonio-scialdone.bsky.social @evahoermanseder.bsky.social Congrats to all the authors of this exceptional paper published @stemcellreports.bsky.social

submitted 4 days ago • 0 comments

Thank you @isscr.org Stem Cell Reports for selecting our work for the March cover! Caption: (1/3) In this issue, Kim and Ramalho-Santos provide a perspective on the history of stem cell transcriptomics. They show that a stemness signature from the early 2000’s foreshadowed hypertranscription.

submitted 5 days ago • 1 comment

In the March issue of Stem Cell Reports, Kim and Ramalho-Santos et al. provide a perspective on the history of stem cell transcriptomics. Read the full issue! www.cell.com/stem-cell-re...

submitted 7 days ago • 1 comment

New research shows salt-inducible #kinases (SIKs) transduce mechanical forces in pancreatic endocrine lineage specifications. www.cell.com/stem-cell-re... @isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social

submitted 12 days ago • 0 comments

Safe CNV removal is essential for the success of hESC-RPE transplantation in #wetAMD. The procedure is well-tolerated, and postoperative #fundus inflammation can be managed effectively. ow.ly/MfbR50V8uRx @isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social

submitted 13 days ago • 0 comments

New study outlines a cardiac #differentiation roadmap, mapping cell states that mimic the human fetal heart. ow.ly/lCkh50V8o2w @isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social

submitted 14 days ago • 1 comment

High-dose #radiation preferentially induces clonal expansion of #hematopoietic progenitor cells over mature T & B cells in mouse bone marrow @isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social @cellpress.bsky.social ow.ly/eywc50V8nE1

submitted 15 days ago • 0 comments

@stemcellreports.bsky.social, @isscr.org's open access journal dedicated to advancing stem cell research, has been named the official conference journal for @bacell3d.bsky.social, taking place from 23-25 June 2025, in Basel, Switzerland. Learn more: www.isscr.org/isscr-news/i...

submitted 15 days ago • 0 comments

We are very excited to announce that @stemcellreports.bsky.social has been named the official conference journal for #BaCell3D!

submitted 15 days ago • 1 comment

New study on #autism and #intellectualdisability highlights the impact of MYT1L mutation on human cortical interneurons, altering #differentiation, maturation, #synapse formation & more. @isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social ow.ly/hOAU50V8mtB

submitted 18 days ago • 0 comments

🔬 🧪The International Society for Stem Cell Research @isscr.org, in partnership with #StemCellReports @stemcellreports.bsky.social invites you to Athens, Greece, on 3-4 April 2025 for a unique symposium to explore the latest neural #StemCell research. ▶️ www.isscr.org/upcoming-pro...

submitted 20 days ago • 0 comments

⏰ Time is running out to apply for the @stemcellreports.bsky.social Early Career Editorial Board! Take your career to the next level by getting involved with the Society journal and gain invaluable experience. Apply by 14 March 👉 bit.ly/4jl22I7