tollkuhn.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

What do 'Lincoln Logs' have to do with earthquakes in Japan, Frank Lloyd Wright, WWII steel rationing & California redwoods? Everything. Lincoln Logs were invented by Frank Lloyd Wright's son, John, in 1916. The two of them worked together on the Imperial Hotel in Tokyo.

submitted 2 days ago • 6 comments

More evidence that distal tuft dendrites provide some form of target/credit signal in hippocampus: www.cell.com/neuron/abstr... #neuroscience 🧪

submitted 3 days ago • 0 comments

Heading back from the CSHL Vision course. I attended as a trainee in 2019, which fundamentally changed my career. I’m so honored to have been invited back as a speaker (“adult”) and am so encouraged by all the bright, curious students and postdocs!

submitted 4 days ago • 1 comment

Octopuses Use Microbial Signals to Guide Complex Behaviors 🧠🧪 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @nbellono.bsky.social @rachellegaudet.bsky.social @naoshigeuchida.bsky.social @neurovenki.bsky.social @dulaclab.bsky.social @harvardbrainsci.bsky.social @cellpress.bsky.social

submitted 5 days ago • 2 comments

👏 Congratulations to @megancarey.bsky.social, principal investigator at @champalimaudr.bsky.social on winning a 2.5M€ #AdvancedGrantInLifeSciences, awarded by the @erc.europa.eu, to develop the project 🧠 SCUPTABELLUM - Sculpting cerebellar activity across timescales.

submitted 5 days ago • 1 comment

Male brains are full of estrogen. Testosterone in the circulation is converted into estrogen by the enzyme aromatase, which is expressed in the brains of all vertebrates.

submitted 5 days ago • 0 comments

Last February, I led a proposal submission that encompassed six months, hundreds of hours, four institutions, a massive team, and and 256 pages. NSF just informed us that the entire Biology Integration Institute program was archived and our proposal would not even be reviewed. With a form email.

submitted 6 days ago • 99 comments

I wrote a review of a recent paper on false discovery and multiple testing correction. liorpachter.wordpress.com/2025/06/16/r...

submitted 6 days ago • 7 comments

New York Times Games Adds New ‘Endorsement’ Puzzle

submitted 6 days ago • 2 comments

THIS IS IT! THIS IS HUGE!! PLAINTIFF'S WIN!! Judge Young rules that the NIH grant terminations at issue in these cases are illegal and therefore vacated. BOOM!

submitted 6 days ago • 12 comments

BREAKING: A federal judge in Massachusetts (the Reagan-appointed William Young) has declared the Trump administration's cuts to NIH grants — ostensibly over Trump's EOs on gender ideology and DEI — are "illegal" and "void." He's ordering many grants restored.

submitted 6 days ago • 106 comments

🚨 BREAKING: Nearly 4 months the NIH cut its first grants, a judge has ruled that the directives and process that led to cuts are arbitrary and capricious. "The explanations are bereft of reasoning — virtually in their entirety... unsupported by [facts]." Each of them are VOID and ILLEGAL, he says.

submitted 6 days ago • 11 comments

Bloomsday

submitted 6 days ago • 1 comment

🧬🌽 Happy Transposon Day! 🌽🧬 Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025

submitted 6 days ago • 4 comments

It's good that Sapporo didn't write the final chapter of SF's beloved steam brewery. But a year after being "saved" by an out-of-town mogul, Anchor is still idle. I argue at @vinepair.com that its next chapter is becoming a cautionary tale about taking even “benevolent” billionaires at face value.

submitted 9 days ago • 2 comments

Our latest review on perimenopause menopause and hormone therapy. What key issues have we missed and how can we do better from education to research to clinical care. With Laura Gravelsins! www.cambridge.org/core/journal...

submitted 6 days ago • 0 comments

Interested in a postdoc position combining computational protein design and molecular simulation? There is an open position in my group at the MRC-LMB in Cambridge, UK. www.nature.com/naturecareer... Feel free to message me with any questions.

submitted 6 days ago • 0 comments

I was searching for "ranked choice voting" but uh

submitted 6 days ago • 5 comments

your sex is on fire

submitted 7 days ago • 1 comment

Most of the news is horrifying and this story from Bourton-on-the-Water is no exception. Brace yourselves: a family of eight arrived for a picnic to find that… other people were also having picnics 😱 www.gloucestershirelive.co.uk/whats-on/wha...

submitted 7 days ago • 166 comments

Our Lab’s five years of work is out! www.cell.com/cell-reports... 🥳 Vasopressin (AVP) excites BNST neurons via oxytocin receptor (and not V1aR or V1bR) 🔬AVP excites CRF-BNST and OTR-BNST neurons 🧠 AVP inputs from SCN and SON excite BNST via OTR 🐁 OTR-BNST neurons reduce anxious arousal in male rats

submitted 9 days ago • 7 comments

the reissued NOFO for the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) is finally published! grants.nih.gov/grants/guide...

submitted 9 days ago • 2 comments

overheard in a discussion with other faculty: "since Roe v Wade was overturned, 80% of the faculty Texas A&M has hired have been male."

submitted 9 days ago • 34 comments

HE’S BAAACK!

submitted 9 days ago • 0 comments

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵 www.nature.com/articles/s41...

submitted 10 days ago • 9 comments

I told you we’d be back

submitted 10 days ago • 1596 comments

been on a run of watching Hitchcock classics (Rear Window, Vertigo, North By Northwest) and it's almost painful to observe the level of thematic and aesthetic sophistication that pop culture aspired to (let alone achieved) at the peak of the midcentury High Modernist moment

submitted 10 days ago • 33 comments

lmfao

submitted 11 days ago • 4 comments

I made my own Atari 2600 game a few years ago in assembly language. One of the most fun & challenging coding exercises given the hardware limitations. In Gene Medic you save patients by editing their DNA #genemedic #atariprojects #atari #atari2600 #genetics #genomics #bioinformatics genemedic.org

submitted 11 days ago • 3 comments

Current genomic deep learning models display decreased performance in cell type-specific accessible regions

submitted 12 days ago • 0 comments

submitted 12 days ago • 10 comments

🚨 NIH head Bhattacharya is about to testify before the Senate Appropriations Committee. We'll be keeping a close watch. Follow along for updates HERE⬇️ (🧵):

submitted 12 days ago • 4 comments

Having obtained consent from all parents and kids, I present: The Plant School Roster. 🧵🌱 First up we have "Luke" the lavender. Luke is a social plant with a deep appreciation for cursive writing (same, Luke, same), and must be spoken to at least twice per day. (This is not his final spot or pot)

submitted 13 days ago • 4 comments

I cant stop smiling - velocity girl youtu.be/lIZ74RnHyb8?...

submitted 13 days ago • 1 comment

Tonight !!! 🎭 📺 📰 Tony Award-nominated “Good Night, and Good Luck” will air live on CNN & CNN International WITHOUT a cable login and on connected TVs and mobile apps beginning at 7PM EST George Clooney plays Edward R. Murrow as he takes a stand against the anti-communist witch hunts of the 1950s.

submitted 15 days ago • 4 comments

Barbara Kruger never misses.

submitted 15 days ago • 1 comment

I’ve been studying gene regulation in primates for over 20 years, and using RNA-seq since 2008 to compare expression across species. We thought we were being careful. We used curated orthologous exons to minimize alignment bias and focused on biologically meaningful comparisons. We were wrong.

submitted 16 days ago • 4 comments