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tonyzador.bsky.social
Neuroscientist at CSHL. Interests: neuroAI, molecular connectomics, & cortical circuits. Co-founder of Cosyne and NAISys meetings.
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has anyone else noticed that since the new Claude update a few days ago, it has become a far worse writer? Claude used to be SO much better than ChatGPT for writing fluent prose. It wrote beautifully. But now it has that same canned LLM feel as ChatGPT. Ugh! @anthropic.com please fix this !

Ever thought about writing for @thetransmitter.bsky.social? You should! It’s a great way to spread your message across the neuroscience community. Here’s how it works: 1️⃣ Read this: www.thetransmitter.org/editorial-po.... 2️⃣ Email a pitch: www.thetransmitter.org/contact-us/

Guardian story about Federal Register issue is up. www.theguardian.com/us-news/2025...

my talk at a physics workshop about genomic bottleneck (a work with @tonyzador.bsky.social and Sergey Shuvaev). any comments on the (half-joking) triple inheritance theory are much appreciated: m.youtube.com/watch?v=Z-zD...

Another great approach for scientist opeds, writing for your hometown paper about the importance of science funding. (Ungated copy in the original thread)

Sad milestone. The once great Washington Post, now reflects its new leadership, canceling ad from groups calling for Trump to fire Musk. www.nytimes.com/2025/02/17/b...

Angie is a reporter with the Transmitter @thetransmitter.bsky.social. I've talked with her before for an article. She is excellent and trustworthy.

Hey neuroscientists: were you, your lab or any of your ongoing projects caught up in any of the latest NIH firings? You can find me on Signal at avaskham.54 if you want to chat. 🧪 #neuroskyence

Do not let up. New Yorkers, you can shape the extent to which a politicized DOJ dictates the leadership and immigrant policies of your state and largest city.

I wrote about how Doge is involved in cutting cancer research www.vanityfair.com/news/story/d...

Dems should propose a law that immediately requires every fed agency to post on @bsky.app account, every outlay with a detailed description, $, and a link to existing gov sites with in depth details Rather than trying to keep Elon out, pre-empt him so he cant miss characterize spending.

A Direct Hit, by @holdenthorp.bsky.social @science.org www.science.org/doi/full/10.... "This is a moment to unite."

🚨NEW: Federal Judge John Bates has ordered the Trump Administration to restore all public health pages to federal websites after removing them in January. REPOST to thank Judge Bates for standing up for public health!

3 cheers for advocates! As we realize that scientists need to do more to unpack the value of science, we need to ... ... stop side-eying scientists who write in lay terms ... stop wishing that scientists would "just science" ... stop belittling scientists who meet the public where they are

"The federal government, from a budgetary perspective, is an insurance conglomerate with a large standing army. That is what we are. That is what we spend money on. Everything else is stuff between the couch cushions." -- @ezrakleinbot.bsky.social (Useful way to think about the fed budget)

👇👇

You are not powerless, and he is not unstoppable. Look at, and learn from, the funding freeze and how quickly he was forced to surrender.

While Musk runs the country, Trump had a productive weekend naming himself Chair of the Kennedy Center, picking the Chiefs to win the Super Bowl, canceling pennies, demanding Google Maps rename Gulf of Mexico, invited only White immigrants from Africa, and saved plastic straws.

This is the most relevant article to NIH and research cuts I’ve seen. Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !” globalnews.ca/news/9793403...

"the fallout includes rescinded contracting jobs in Fayetteville, North Carolina, and Austin; layoffs at an independent-living facility in West Virginia that relies on federal funding to pay staffers; and furloughs at after-school programs in Maine" www.washingtonpost.com/business/202...

Senator from Kansas thinks that some foreign aid is important. Wonder why?

for those who want to wander through the weeds of the history of indirect costs at the NIH, this is fascinating 5 minute read goodscience.substack.com/p/indirect-c...

I have a confession . . . I was an “overhead cost”. I was a beaker washer, agar plate pourer, research secretary. I was paid by “overhead cost” fees. Loved it. Those “overhead cost” jobs allowed this rural kid to become a physician. Please tag how #OverheadCostJob impact u.

The United States by virtue of a bipartisan commitment to biomedical research created one of the most vibrant, productive research ecosytems in the world. People came from all over to study here, do research here. It was a monumental accomplishment by both parties. 1/

lol elon musk's dealer is running DOE

"I didnt vote for cancer"

everyone needs to call their representatives, and reach out onto traditional and social media. Medical research that saves lives is not a red state/blue state issue.

Contacting your congressperson is fine. But contacting your local TV station is better. One interview on local TV saying your congressperson should act is worth 1,000 office calls.

mobilize ! NIH funding supported -> 412,041 jobs -> $92.89 billion economic activity ($2.46 for every $1 ) -> we are a $100B industry. Flood your congress people with letters/emails Curing disease is not a red/blue state issue.

Just learned from NPR that the federal government is the largest employer in the great Kansas City area, for example. I found it helpful to be reminded that, of course, this isn’t just about people who work and live in DC. Federal employees are in all of our communities.

Having funded teams/contracts that required six figure+ funds a few times now, these numbers SOUND really huge in isolation to normal folks but they're not! Don't make floating numbers! I like to say things like this: "A cancer lab is basically a small business, with many jobs created by each grant"

"You know how tech startups raise millions of dollars to get going? So big science labs - the ones that make the medicine! - are so efficient they run on less than half of that!"

An irony of the push to lower overhead rates on grants to reduce waste / fraud is that a significant amount of overhead goes to “grant compliance” because of a Bush II focus on grant oversight. Every university has a huge office filled with staff ensuring no grant dollar goes where it’s not allowed.

NIH funding supported : *** 412,041 jobs *** *** $92.89 billion in new economic activity*** *** $2.46 for every NIH $1 spent.*** We are a $100B industry. Let's act like it How about, at a bare minimum, we all just call our congressional reps www.unitedformedicalresearch.org/annual-econo...

NIH in New York New York Awards - $3.59 B Jobs Supported - 29,298 Economic Activity Supported - $7.97 B www.unitedformedicalresearch.org/nih-in-your-...

Oops 😬

SCOOP: A US Treasury threat intelligence analysis has designated DOGE staff an ‘insider threat'. An internal email reviewed by WIRED calls DOGE staff's access to federal payments systems “the single biggest insider threat risk the Bureau of the Fiscal Service has ever faced.”

Suddenly we all need to become experts in how indirect costs are calculated grants.nih.gov/grants/guide...