tylervkent.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

The genomic imprint of chromosomal inversions and demographic history in island populations of deer mice https://www.biorxiv.org/content/10.1101/2025.04.18.649517v1

submitted 5 days ago • 0 comments

New preprint from the lab: 'Domestication shaped the chromatin landscape of grain amaranth'. #domestication #chromatin #amaranth www.biorxiv.org/content/10.1...

submitted 6 days ago • 1 comment

Mosquito sex under lock and key https://www.biorxiv.org/content/10.1101/2025.04.11.648401v1

submitted 11 days ago • 0 comments

Comparative gene annotation of 304 species of Drosophilidae https://www.biorxiv.org/content/10.1101/2025.04.14.648771v1

submitted 12 days ago • 0 comments

Published version of our spatial simulations paper led by Jiseon Min and Elsie Chevy is up 🔐! This was such a fun paper to be a part of and a valuable resource to folks thinking population simulations of all kinds, even non-genetic ones! onlinelibrary.wiley.com/doi/epdf/10....

submitted 12 days ago • 1 comment

I was so fortunate to work with @rejectresubmit.bsky.social on wrapping up some work from my postdoc with @stepheniwright.bsky.social. Check out our very cool paper pulling apart the history of sex chromosomes in Rumex! academic.oup.com/evlett/artic...

submitted 13 days ago • 0 comments

Our perspective on meiotic drive and the evolution of chromosome numbers across plants is now out at Molecular Ecology! With Sylvia Kinosian! onlinelibrary.wiley.com/doi/10.1111/...

submitted 17 days ago • 2 comments

With @hybridzones.bsky.social & @jenncoughlan.bsky.social, we have been working on an update to Daven Presgraves' influential 2010 review on hybrid incompatibilities (shorturl.at/cJndf). The preprint is available here (shorturl.at/DTC48) with an updated table of almost 100 incompatibilities!

submitted 17 days ago • 1 comment

It’s also worth noting that Colossal received funding from North Dakota when Burgum was governor, where as far as I can tell, the Colossal “reserve” is

submitted 19 days ago • 0 comments

Excited to see the final version of this paper with @samurscicop.bsky.social and Daniel Matute out in @genomebiolevol.bsky.social! We took a dive into the complicated demographic history of Aedes aegypti mosquitoes and its impact on the distribution of genetic diversity doi.org/10.1093/gbe/...

submitted 20 days ago • 3 comments

Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...

submitted 20 days ago • 1 comment

Carney: The system of global trade anchored on the United States.. is over. Our old relationship of steadily deepening integration with the United States is over. The 80 year period when the United States embraced the mantle of economic leadership… is over.

submitted 24 days ago • 1193 comments

Grundler et al propose a new method to infer the geographic position of all our genetic ancestors www.science.org/doi/10.1126/... building on a method by Wohns et al www.science.org/doi/10.1126/.... My thoughts on the approach: www.science.org/doi/epdf/10.....

submitted 30 days ago • 1 comment

🚨 New preprint alert! 🚨 We introduce ConfuseNN, a method to interpret convolutional neural network (CNN) inferences in population genomics using data shuffling. Curious about how CNNs make decisions in genomic analyses? Check it out! 🧵👇https://www.biorxiv.org/content/10.1101/2025.03.24.644668v1

submitted 31 days ago • 1 comment

Paper "Triploid bridges enable gene flow in mixed-ploidy populations of Cardamine amara" published in Molecular Ecology! doi.org/10.1111/mec.... The study reveals how rare triploids help overcome ploidy barriers and mediate gene flow between diploid and tetraploid populations.

submitted 33 days ago • 0 comments

Reproductive barriers can evolve despite gene flow. A combination of genomics and behavioural assays shows two mitonuclear incompatibilities originated via ancient hybridization that underlie hybrid inviability in a pair of closely related swordtail fishes www.nature.com/articles/s41...

submitted 32 days ago • 0 comments

Interested in gene expression, machine learning, natural selection, and evolution? My former student, Georgia Henry just published a paper that may interest you. Her goal: understand how natural selection acts on the transcriptome, within a single generation experiment, in the field.

submitted 33 days ago • 1 comment

stdpopsim v0.3.0 is out! You can now mix and match your simulations of different demographic histories with published distributions of fitness effects along with gene annotations, and you can even throw in sweeps for good measure. Check out the new manuscript for more info: doi.org/10.1101/2025...

submitted 34 days ago • 0 comments

Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses www.nature.com/articles/s41...

submitted 36 days ago • 0 comments

Hitchhiking in facultative sexuals e.g. baker's yeast: can reduce diversity across the genome and contribute to Lewontin’s paradox. Results relevant to anyone (e.g. me) who has looked but found few if any strong sweeps. www.biorxiv.org/content/10.1...

submitted 39 days ago • 0 comments

New lab paper in press: crossover dynamics have different genetic bases in female pigs. RNF212 is associated with crossover rate and interference, but... SYCP2, MEI4 and PRDM9 are associated with crossover positioning and intra-chromosomal allelic shuffling. www.nature.com/articles/s41...

submitted 39 days ago • 1 comment

Fascinating, really thought-provoking work by Trevor Cousins, @aylwyn-scally.bsky.social and Richard Durbin, now out in @naturegenet.bsky.social 🧪🧬 Deep ancestral structure shared by all modern humans www.nature.com/articles/s41...

submitted 40 days ago • 1 comment

Listen: Chicago lawyers argued in federal court that ICE has violated immigration law and the constitutional rights of 22 Midwesterners. Reset gets the latest on this and on the case of Julio Noriega, a U.S. citizen who was arrested by ICE in suburban Berwyn. www.wbez.org/reset-with-s...

submitted 41 days ago • 1 comment

Excited to share our new preprint on bioRxiv! 🚀 We explore the genomic basis of serpentine adaptation in two ploidies and species of Alyssum and reveal evolutionary convergence with Arabidopsis. Check it out! 🌿🔬 #evolution #genomics #arabidopsis #serpentine

submitted 57 days ago • 0 comments

I’m very proud and happy to share the first paper of my PhD with @millanek.bsky.social that is now published in the latest issue of the journal Evolution @journal-evo.bsky.social. academic.oup.com/evolut/artic...

submitted 44 days ago • 1 comment

I'm excited to share our new preprint on the molecular evolution of heterodichogamy in two wingnut genera of Juglandaceae. Heterodichogamy features two morphs synchronously alternating male and female flowering phases in time to generate disassortative mating. doi.org/10.1101/2025...

submitted 47 days ago • 2 comments

Every day I wake up to new horrors and my Id demands blood but I have written this paper on pseudo-overdominance in polyploids instead www.biorxiv.org/content/10.1...

submitted 52 days ago • 2 comments

Nature research paper: Evolution of temperature preference in flies of the genus Drosophila https://go.nature.com/4i1VQn9

submitted 53 days ago • 0 comments

BIG NEWS! The Mosquito Cell Atlas preprint is live! 🦟🧬 My first senior author paper! Massive and accessible snRNA-seq dataset and a lot of cool mosquito biology. A true collaborative achievement! #MCA biorxiv.org/content/10.1... See @oliviagoldman.net thread here

submitted 53 days ago • 0 comments

Do you sequence genomes? Then this is a must-read: www.biorxiv.org/content/10.1...

submitted 53 days ago • 2 comments

#standwithUkraine

submitted 58 days ago • 0 comments

Happy to share our work exploring the genetic basis of dengue susceptibility in Aedes aegypti and revealing the antiviral role of a cytochrome P450. www.biorxiv.org/content/10.1... It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️

submitted 58 days ago • 2 comments

Feb 28 deadline for junior folk to apply for travel to the annual @smtpb.bsky.social meeting on Mathematical & Theoretical Population Biology in Chicago. For those paying their own travel & accommodation (no registration!) it is March 14. Apply here: www.nitmb.org/modeling-and... @nitmb.bsky.social

submitted 61 days ago • 0 comments

Convergent floral scent loss following transition to hummingbird pollination in spiral gingers (Costus). I had so much fun on this project with @kathleenmkay.bsky.social and Santiago Ramirez and am thrilled to see it published now in @MolBioEvol! academic.oup.com/mbe/article/...

submitted 61 days ago • 3 comments

I am thrilled to share our new review on holocentric chromosomes. It was a lot of fun to write it together with Ines Drinnenberg! Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...

submitted 66 days ago • 3 comments

🥳Just published @nature.com. Over 25 years after the discovery of SPO11 as the enzyme responsible for initiating meiotic recombination, we finally succeeded in reconstituting its DNA cleavage activity.🧵 www.nature.com/articles/s41...

submitted 67 days ago • 7 comments

Upon learning that yesterday would be my last day as a program officer at the National Science Foundation, I shared this parting message with my colleagues. The next few months will be frenetic and stressful for them. Here are some things that you can do to help them with the mission ahead. (1)

submitted 67 days ago • 67 comments