Profile avatar
vineytj.bsky.social
Neuroscientist - spatial #memory, cell types, amyloids, #dementia, #brain rhythms PI @ University of Oxford https://scholar.google.com/citations?hl=en&user=tgCeCVwAAAAJ&view_op=list_works&sortby=pubdate
22 posts 629 followers 207 following
Prolific Poster
Conversation Starter

@physoc.bsky.social has a starter pack of physiologists. Hooray!! go.bsky.app/2KU1XD6

Exciting new work from the Dominantly Inherited Alzheimer Network describing a PSEN2 mutation carrier who has “escaped” disease. Importantly lessons to learn for AD resilience!

I am delighted to share that our latest research has been published in Acta Neuropathologica. Please have a read: doi.org/10.1007/s004... #Neuropathology #AlzheimersDisease #Neurodegeneration #Glia #HumanBrain #Immunity

Thanks to all of the NIHers and their friends who reached out to me. I am still here (DM me or Signal jeremymberg.78) I still have a very incomplete picture but based on what I have been told, the damage to NIH and to many wonderful people who work(ed) there is/was impossible for me to imagine 1/n

Grid cells have a geometry in time. Thanks to @azvollan.bsky.social l & @rjgardner.bsky.social for this heroic discovery. @ercresearch.bsky.social #KiloNeurons @m-bmoser.bsky.social @kavlintnu.bsky.social @nature.com @kavlifoundation.bsky.social www.nature.com/articles/s41...

Launch of the Centre for Global Epilepsy www.oxfordmartin.ox.ac.uk/news/oxford-...

Don’t miss this upcoming #LMBSeminar by Maria Grazia Spillantini, Professor of Molecular Neurology at the University of Cambridge. At 11am (GMT) Monday 10th Feb, Maria will discuss ‘Alpha-Synuclein and its Aggregation: Past, Present and Future’ More details: www2.mrc-lmb.cam.ac.uk/news-and-eve...

Synaptic Targets and Cellular Sources of CB1 Receptor and VGLUT3 Expressing Nerve Terminals in Relation to GABAergic Neurons in the Human Cerebral Cortex doi.org/10.1111/ejn.... Delighted that this paper is out - includes n=120 tested interneurons that were recorded and labelled in human cortex

Emails can be very distracting. The only way I manage is to have no notifications on devices and try to check only at specific times of the day. Anything important I assign to a space in my calendar. MS Teams is used for the lab

Here is the MIT Tech Review article covering the data collection linked to this new Phd Opportunity at our new International Centre for NeuroArchitecture and NeuroDesign: www.technologyreview.com/2024/09/13/1...

I'm delighted to share this special issue on scientific histories of hippocampal research in the journal Hippocampus - lots of interesting stories and a great resource for trainees. Huge thanks to Mike Hasselmo and Lynn Nadel for their vision and leadership! onlinelibrary.wiley.com/doi/toc/10.1...

A must-read article for anyone working on #tau and #dementia. I remember Linde Jacobs' important and moving talk at the Tau2024 conference in Washington DC. Her presence at the meeting underscored how important it is to fund and conduct research on tauopathies

A striking example of similar patterns but at massively different scales. Left, a star orbited by exoplanets taken by ESO’s Very Large Telescope (Bohn et al. www.eso.org/public/irela...). Right, β-amyloid42 immunoreactivity in human cerebral cortex (B. Sarkany and T. Viney, University of Oxford)

Fantastic journey through the history of hippocampal extra cellular recording techniques and the search for cell assemblies by Bruce McNaughton. onlinelibrary.wiley.com/doi/10.1002/...

Neurobiotin, drawn by Dr Lizzie Burns. This synthetic #molecule is a derivative of biotin (vitamin B7). It can be delivered into single #brain cells in order to study their architecture and trace the fine processes within and across brain regions, revealing hidden details of the nervous system.

I got to meet Horace Barlow in 2005 just before starting my PhD. We met in his office and he showed me some movies of black dots moving across a grey background. I didn't fully understand the significance until later. I have always recorded single neurons and still listen to them via loudspeaker

Science’s 2024 Breakthrough of the Year is lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months. Learn more about this year's #BOTY and other big advances in science: scim.ag/3BrCtUn

“The coexistence of multiple astrocyte phenotypes suggests that we should address astrocyte heterogeneity, stratify astrocyte subtypes, and consider multiple astrocyte targets for developing biomarkers.” I had the honor of commenting on the paper of the year by @sdas617.bsky.social et al.👇

Ants integrate proprioception as well as visual context and efference copies to make robust predictions #sensorimotor www.nature.com/articles/s41...

Publishing requires constant innovation and renewal to remain relevant. We are concerned by the action that Clarivate is taking in regard to @elife.bsky.social but not because eLife may not be eligible for an Impact Factor but because of the chilling effect on innovation. sfdora.org/2024/11/25/c...

🧠 130 people now in this UK Dementia Starter Pack! 🧠 📈 (50 more than 2 days ago!) 📈 A great mix of Profs/PIs/Post-docs/PhDs/Technicians. Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋 go.bsky.app/S6FfsTp

Postmortem evidence that higher brain GFAP levels are associated with higher brain amyloid burden 👇👇👇👇 link.springer.com/article/10.1...

Pleased to say our study led by James Street showing a requirement for the LGN pathway for visual landmark control of head direction cells is now published! physoc.onlinelibrary.wiley.com/doi/10.1113/...

Some precious mouse brain sections currently being processed with diaminobenzidine to follow axons of juxtacellularly labelled cells.

How the #brain talks to the #gut and vice versa! 🧪🧠💩 Check out the great primer on gut-brain communication and #interoception by @amberalhadeff.bsky.social and Nilay Yapici 👇👇👇 www.cell.com/current-biol...

The main output of the hippocampus is subcortical. Today, for the last class on the neurophys of navigation & mem, we will discuss this fantastic paper by @davidtingley.bsky.social (Buzsaki Lab) showing a link btw hippocampal sharp wave-ripples & glucose release. www.nature.com/articles/s41... 1/n

some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed? go.bsky.app/MHtJzeC

There are lots of us missing, but so many joining so quickly Please do share, and comment below to be added go.bsky.app/5f2V6L6 (microglia starter pack also here by @mancusorenzo.bsky.social - bsky.app/starter-pack...)

Fortification of flour with folic acid is very welcome news. Folic acid in combination with B12 and B6 lowers #homocysteine levels - a risk factor for #dementia e.g. pmc.ncbi.nlm.nih.gov/articles/PMC5836397/

🧠Re-sharing this as the list is growing. 🌲 Let me know if I've left you out - or if you think I should add someone! 🧠 go.bsky.app/S6FfsTp

go.bsky.app/LdtUYZS I created a starter pack for the growing community of hippocampus physiologists that have joined the great migration. Also included the physiology-adjacent. Tell me who I haven’t found yet

🧠 barriers & neurovasculature starter pack - please reply here if you are not on it yet & would like to be added 😊 go.bsky.app/RB6RXKy

Time to say 👋🏻 I guess! I’m a group leader at UCL Queen Square Institute of Neurology, my team is interested in using stem cell models to understand the mechanisms of Alzheimer’s & other dementias. Expect science, cellfies, running & cat photos (I hope they’re still welcome here!)

Just put together the beginnings of a systems & behavior neuro starter pack (focus on rodent work) - obviously a lot of people missing, and most included are in my own little bubble, so if you want to be added do reply here! go.bsky.app/Hxpe53o

are there systems neuro / hippocampus / circuits starter packs?

Finally out in Royal Society Open Science: Our perspective / manifesto article: "Ecological brain: reframing the study of human behaviour and cognition" We need to connect - taking research to the real-world with bringing the real-world into the lab royalsocietypublishing.org/doi/epdf/10....

Introduction for Bluesky: I am a neuroscientist specialising in #neuroanatomy, #neurophysiology, and #neurodegeneration at the Department of Pharmacology, University of Oxford. Favourite techniques: in vivo juxtacellular labelling, #immunohistochemistry. My group studies both human and rodent #brain

Pleased to share our #neuroscience preprint on how tau pathology affects head direction cells of the anterodorsal thalamus and induces disorientation, an early sign of #dementia