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yukselurun.bsky.social
Medical Oncologist 🔬 @AnkaraUni 🎓 Advocate for #Diversity & #Equity 🌟 Genitourinary Cancer
152 posts 518 followers 105 following
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The reflection of the Washington Monument, Lincoln’s legacy, and the timeless serenity of nature. #WashingtonDC #lincoln @ascocancer.bsky.social @oncoalert.bsky.social

🧬 Liquid Biopsy in Clinical Practice: Past, Present & Future🩸 New review explores the evolution, applications, and future directions of liquid biopsy in oncology. Key insights in: ✅ Circulating Tumor Cells ✅ Circulating Tumor DNA ✅ Exosomes @christianrolfo.bsky.social @yukselurun.bsky.social

Trends in #ProstateCancer Incidence and Mortality Rates Out on JAMA Network jamanetwork.com/journals/jam... Findings underscore need for improved prostate cancer screening strategies to address the rising incidence of distant-stage disease Ping @yukselurun.bsky.social @barbaramelao.bsky.social

The very first post-ASCO GU meeting this year ! @yukselurun.bsky.social

🚨 Excited to join @myESMO #ESMOOnAir to discuss the latest in advanced urothelial cancer with an incredible panel! 📅 19 Feb 2025 | 🕡 18:30 CET Don't miss it! @oncoalert.bsky.social

Largest AI Mammography Trial: Game-Changer! 🔍 105,934 women screened ↗️ 29% more cancers detected ↘️ 44% reduction in screen-reading workload ✅ No rise in false positives AI is reshaping breast cancer screening! #BreastCancer #AI #Oncology #Cancer @oncoalert.bsky.social @oncbrothers.bsky.social

5 articles suggested by Yüksel Ürün @yukselurun.bsky.social oncodaily.com/blog/yuksel-... #NeoadjuvantChemotherapy #OncoDaily #Oncology #OvarianCancer #PrecisionMedicine #ASCO #Cancer #Chemotherapy #ClinicalTrials #EsophagealCancer #FightAgainstCancer #Medicine #Health

Perioperatie FLOT chemotherapy improved overall survival in resectable esophageal adenocarcinoma compared to preop chemoradiotherapy. Progression-free survival also favored FLOT @oncoalert.bsky.social @mcuban.bsky.social @drchoueiri.bsky.social @oncbrothers.bsky.social www.nejm.org/doi/full/10....

Bladder preservation matters in high-risk NMIBC after BCG failure. A Phase 2 study on intravesical durvalumab shows promise: 1-y high-grade relapse-free rate of 39%, with minimal toxicity. Further studies needed. #BladderCancer @oncoalert.bsky.social @erplimackmd.bsky.social doi.org/10.1016/j.eu...

🔵1 in 3 men experience PSA persistence or relapse within 10 years post-radical prostatectomy. 🔵Early relapse (<2 years) = higher PCa death risk (8.5%) vs. late relapse (>5 years, 1.4%). 🔵Life expectancy and relapse timing guide treatment. #ProstateCancer #Oncology @oncoalert.bsky.social

34% drop in cancer death rates since 1991 saved 4.5M lives—but the fight isn’t over! 🚨 Rising cancer cases in younger adults (<65) and women shift the burden: middle-aged women now at higher risk than men, and young women nearly 2x more likely to be diagnosed than men. @oncoalert.bsky.social

Five articles suggested by Yüksel Ürün @yukselurun.bsky.social oncodaily.com/science/225249 #BladderCancer #BreastCancer #Cancer #Cytokines #Medicine #Epidemiology #ESMO #GlobalConsortium #Oncology #GBMGrowth #Health #TransurethralResection #MagneticResonanceImaging #MedOnc #mpMRI #OncoDaily

🚨 Disinformation threatens public health! Time to stand up for science and truth. #PublicHealth @oncoalert.bsky.social

Florence at night: A masterpiece of art and architecture that transcends time. #Florence #Italy #architecture #Renaissance

🔻 Cancer mortality declined, averting 4.5M deaths since 1991, thanks to smoking reduction, earlier detection, & better treatments. 🔺 However, alarming disparities persist 🚺 Cancer incidence is rising in women @oncoalert.bsky.social acsjournals.onlinelibrary.wiley.com/doi/full/10....

Can mpMRI replace TURBT for faster treatment in MIBC? A randomized study shows that the mpMRI-first approach reduced the time to treatment by 45 days (53 vs. 98 days). No harm to non-MIBC patients. A game-changer for staging? #Oncology @oncoalert.bsky.social ascopubs.org/doi/10.1200/JC…

🌱 A healthy lifestyle reduces risks even among those genetically predisposed! @JNCI_Now @OncoAlert doi.org/10.1093/jnci/d…

Implementation of AI for cancer detection in population-based mammography screening @yukselurun.bsky.social oncodaily.com/blog/impleme... #AI #Cancer #Medicine #Health #OncoDaily #Oncology

High doses of vitamin C, high doses of vitamin D, ivermectin, and fenbendazole have recently been promoted both domestically and internationally as the “new recipe” for cancer treatment. However, such approaches are nothing more than exploitation of people’s hopes with unproven methods.

“Competition in the digital age and among universities is increasingly blurring the line between inspiration and plagiarism.” -Conversations on Writing, Ursula K. Le Guin

Your most enduring professional legacy is not your CV — there will always be others with more papers, grants, earnings. Your most *enduring* professional legacy is...your mentees! 🔸It's #NationalMentoringMonth! Celebrating #oncology mentors, guiding today's leaders and shaping cancer care's future!

How fiber helps our gut! Short-chain fatty acids like butyrate (produced from fiber in foods like oats, bananas, and onions) help gut health. They activate genes for repair and slow cancer cell growth while supporting healthy cells. @oncoalert.bsky.social rdcu.be/d5Mlz

Congratulations Hatice and the entire team for this impactful study on treatment sequencing in mCRPC! Important insights for clinical practice! @oncoalert.bsky.social @apccc.bsky.social @oncbrothers.bsky.social @mjmorrismd.bsky.social @drchoueiri.bsky.social doi.org/10.1016/j.ej...

Statins improve outcomes in cancer patients on ICIs! 📊 Meta-analysis of 46,154 patiens shows better OS & PFS with statin use. #Cancer #Immuntherapy #Statins @oncoalert.bsky.social @drchoueiri.bsky.social @viveksubbiah.bsky.social @oncbrothers.bsky.social doi.org/10.1200/OP-24-…

AI is HERE! 🇩🇪 In mammography screening, AI-supported double reading detects 17.6% more breast cancer with better recall & PPV rates. A true game-changer! @oncoalert.bsky.social @naturemedicine.bsky.social @breastcancernow.bsky.social @tmprowell.bsky.social nature.com/articles/s4159…

The OncoAlert Video Journal: "Deep Learning Model for Predicting Immunotherapy Response in Advanced #NSCLC Non−Small Cell #LungCancer 🫁" This Week @biagioricciutimd.bsky.social 🇺🇸of @danafarbernews.bsky.social Guides us through his paper out on JAMA oncology www.youtube.com/watch?v=LuD4...

PARP inhibitors + hormonal therapy boost OS & PFS in BRCA1/2-mutant & HRR-deficient mCRPC. 🧬Olaparib, Talazoparib, & Rucaparib lead efficacy despite AEs. @oncoalert.bsky.social @christianrolfo.bsky.social @apccc.bsky.social @asharpmedonc.bsky.social @weoncologists.bsky.social

Belzutifan + Cabozantinib shows promising 70% ORR in treatment-naive advanced ccRCC (LITESPARK-003). #KidneyCancer #Oncology #Cancer @oncoalert.bsky.social @drchoueiri.bsky.social @kidney-cancer.bsky.social @dfcibreastonc.bsky.social

Santa doing post-delivery quality checks! 🎅🎁 @newyorker.com

🖥️Machine learning meets oncology: SCORPIO predicts immune checkpoint inhibitor outcomes using routine blood tests and clinical data, outperforming TMB & PD-L1 in diverse cancers. 🧬🎯 #Cancer #Oncology @oncoalert.bsky.social @viveksubbiah.bsky.social @ptarantinomd.bsky.social rdcu.be/d5rOC

Overtreatment of prostate cancer in the VA: While low-risk cases decreased, overtreatment of men with limited life expectancy & higher-risk disease rose, mainly with radiotherapy. Clinicians must balance treatment benefits vs toxic effects. @oncoalert.bsky.social jamanetwork.com/journals/jam...

Asidik diyetler kansere yol açar mı? Gerçekler ve yanlış anlamalar! Kanserden korunmak için mucize bir diyet yok; dengeli beslen, hareket et, bilime kulak ver! Daha fazla bilgi için @YouTube kanalımıza abone olun! #Kanser #Sağlık #Bilim #YaşamTarzı youtube.com/shorts/PtI87...

Alcohol consumption increases the risk of developing 7 cancer types, including mouth, throat, liver, breast (in women), and colon. Every choice matters. #Oncology #CancerPrevention @oncoalert.bsky.social

Ever heard of an iron lung? It helped polio patients breathe. Thanks to vaccines, it’s now obsolete. Let’s keep it that way—don’t skip your shots! #VaccinesWork #Health @oncoalert.bsky.social @tmprowell.bsky.social @ptarantinomd.bsky.social @jameabraham.bsky.social @drchoueiri.bsky.social

In science, the difference between knowing and believing is crucial. Believing relies on assumptions or faith while knowing demands evidence and proof. Science thrives on questioning to transform beliefs into verified knowledge!

MECCA trial: 💊💊💊Despite past views of endocrine therapy as antagonistic, Metronomic capecitabine + AI significantly improves PFS (20.9 vs. 11.9 mo) & OS in HR+/HER2- MBC. @oncoalert.bsky.social @oncbrothers.bsky.social @ptarantinomd.bsky.social @tmprowell.bsky.social doi.org/10.1200/JCO.24…

Cancer vaccines are showing promise at last! Trials are underway against skin, brain, and lung tumors. @theeconomistevents.bsky.social @oncoalert.bsky.social @erictopol.bsky.social @oncbrothers.bsky.social @viveksubbiah.bsky.social @drchoueiri.bsky.social economist.com/science-and-te…

🧬💊2024 FDA approvals highlight cancer as a priority: 15 (30%) novel drugs, including the 11th PD1/PDL1 blocker. 🎯 Our mission is clear: ensure the right treatment is available and accessible to every patient. Equity in care is non-negotiable. @oncoalert.bsky.social @oncbrothers.bsky.social

Genomics & imaging innovations are transforming cancer care! @thelancet.bsky.social @oncoalert.bsky.social sciencedirect.com/science/articl…

Conventional imaging understages high-risk nonmetastatic prostate cancer. ☢️PSMA-PET was positive in 84% of cases, detecting M1 disease in 46%, polymetastatic in 24%. #ProstateCancer #PSMAPET #Oncology @oncoalert.bsky.social @mjmorrismd.bsky.social doi:10.1001/jamanetworkopen.2024.52971

Early-onset colorectal cancer (<50 yrs) is rising, linked to factors like Western diets, obesity, and gut microbiota changes. Prevention & early detection strategies are vital. #ColorectalCancer #Oncology #CancerPrevention @oncoalert.bsky.social @oncbrothers.bsky.social rdcu.be/d49OZ

Adjuvant IO trials in muscle-invasive urothelial carcinoma: IMvigor010: Atezo DFS HR 0.89, OS HR 0.85. CheckMate 274: Nivo DFS HR 0.71, OS HR 0.76. AMBASSADOR: Pembro DFS HR 0.73, OS HR 0.98. #oncology #cancer @oncoalert.bsky.social @oncbrothers.bsky.social @erplimackmd.bsky.social @nejm.org

AMBASSADOR Trial: Adjuvant pembrolizumab improved disease-free survival in high-risk muscle-invasive urothelial carcinoma post-surgery (29.6 vs 14.2 months; HR 0.73). Grade ≥3 AEs: 50.6%. @nejm.org @oncoalert.bsky.social @erplimackmd.bsky.social @drchoueiri.bsky.social @oncbrothers.bsky.social

Submitting a manuscript feels like a victory… until Reviewer 2 steps in. 😅 #academia @oncoalert.bsky.social

From 'undruggable' to 'druggable': RAS oncogenes are stepping into the spotlight with promising new therapies! 🔬 (Figure: Frequency of RAS mutations in major cancer types.) #Cancer #research #Oncology @oncoalert.bsky.social @viveksubbiah.bsky.social #precision www.cell.com/trends/cance...

As Pooh said: ‘Today is my favorite day.’ Choose to stay present, because there’s no time more precious than now. 🌟

Cancer could double by 2070, with the largest rise in low-HDI countries. Prevention strategies targeting smoking, obesity, and HPV are urgent to avert millions of cases. #CancerPrevention #Oncology #GlobalHealth @oncoalert.bsky.social rdcu.be/d49ON

May the new year shine as brightly as the stars in the winter sky. Here’s to growth, resilience, and endless possibilities! 🌟🎄 #HappyNewYear2025

Yeni yıl, umutlarımızın yıldızlar gibi parladığı bir gökyüzü olsun. Sevgi, sağlık ve huzur dolu bir yıl dileğiyle… Mutlu Yıllar! 🌟🎄 #MutluYıllar #2025