Recently we have been doing lots of work on how modern #AI methods can be applied to studying virus evolution, so it felt like great timing to write a perspective about it! Very happy to see our paper as editor's pick in JVI!🥳🥳 doi.org/10.1128/jvi.... - ThreadSky

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spyroslytras.bsky.social • 118 days ago

Recently we have been doing lots of work on how modern #AI methods can be applied to studying virus evolution, so it felt like great timing to write a perspective about it!

Very happy to see our paper as editor's pick in JVI!🥳🥳

https://doi.org/10.1128/jvi.01601-24

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divyav.bsky.social•118 days ago

📌

spyroslytras.bsky.social•118 days ago

Among other cool advances we highlight two of our recent applications of protein language models to studying the evolutionary potential of SARS-CoV-2's Spike protein:

spyroslytras.bsky.social•118 days ago

1. CoVFit: A Protein Language Model for Exploring Viral Fitness Landscapes

led by Jumpei Ito

https://www.biorxiv.org/content/10.1101/2024.03.15.584819v1

spyroslytras.bsky.social•118 days ago

2. From a single sequence to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2 protein sequences

led by @kieranlamb.bsky.social

https://www.biorxiv.org/content/10.1101/2024.07.05.602129v2

spyroslytras.bsky.social•118 days ago

I wrote this quote a while back, but it hits harder as of recent political events... :

spyroslytras.bsky.social•118 days ago

"Given the general failure to learn the importance of sufficient levels of widespread sequencing to understand novel viruses, it is thus optimistic to expect that the same amount of effort will be put into understanding the next virus that spills over into humans."

spyroslytras.bsky.social•118 days ago

With @kieranlamb.bsky.social, Jumpei Ito, @grovearmada.bsky.social, Ke Yuan, @systemsvirology.bsky.social, @bljog.bsky.social , and @davidlrobertson.bsky.social

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