Drug target genes for a given disease share enrichments with genetically implicated genes. We also show vignettes of genes that are genetically associated to a disease, expressed in disease-enriched structures, and targets for known drugs.
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In summary, we show spatial transcriptomics data provides and important layer of insights for functional interpretation of GWAS data. We hope to see broad use of the tools and resources we compiled, and look forward to even broader applications as the ST data sets improve in scope and resolution.
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